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References for PMC Articles for PubMed (Select 22025551)


A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyperresponsiveness.

Gordon ED, Sidhu SS, Wang ZE, Woodruff PG, Yuan S, Solon MC, Conway SJ, Huang X, Locksley RM, Fahy JV.

Clin Exp Allergy. 2012 Jan;42(1):144-55. doi: 10.1111/j.1365-2222.2011.03840.x. Epub 2011 Aug 22.


Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β.

Kitamura H, Cambier S, Somanath S, Barker T, Minagawa S, Markovics J, Goodsell A, Publicover J, Reichardt L, Jablons D, Wolters P, Hill A, Marks JD, Lou J, Pittet JF, Gauldie J, Baron JL, Nishimura SL.

J Clin Invest. 2011 Jul;121(7):2863-75. doi: 10.1172/JCI45589. Epub 2011 Jun 6.


Effect of bronchoconstriction on airway remodeling in asthma.

Grainge CL, Lau LC, Ward JA, Dulay V, Lahiff G, Wilson S, Holgate S, Davies DE, Howarth PH.

N Engl J Med. 2011 May 26;364(21):2006-15. doi: 10.1056/NEJMoa1014350.


A large-scale, consortium-based genomewide association study of asthma.

Moffatt MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, Heath S, von Mutius E, Farrall M, Lathrop M, Cookson WO; GABRIEL Consortium.

N Engl J Med. 2010 Sep 23;363(13):1211-21. doi: 10.1056/NEJMoa0906312.


Overexpression of Smad2 drives house dust mite-mediated airway remodeling and airway hyperresponsiveness via activin and IL-25.

Gregory LG, Mathie SA, Walker SA, Pegorier S, Jones CP, Lloyd CM.

Am J Respir Crit Care Med. 2010 Jul 15;182(2):143-54. doi: 10.1164/rccm.200905-0725OC. Epub 2010 Mar 25.


The integrin-blocking peptide RGDS inhibits airway smooth muscle remodeling in a guinea pig model of allergic asthma.

Dekkers BG, Bos IS, Gosens R, Halayko AJ, Zaagsma J, Meurs H.

Am J Respir Crit Care Med. 2010 Mar 15;181(6):556-65. doi: 10.1164/rccm.200907-1065OC. Epub 2009 Dec 17.


Human airway smooth muscle cells from asthmatic individuals have CXCL8 hypersecretion due to increased NF-kappa B p65, C/EBP beta, and RNA polymerase II binding to the CXCL8 promoter.

John AE, Zhu YM, Brightling CE, Pang L, Knox AJ.

J Immunol. 2009 Oct 1;183(7):4682-92. doi: 10.4049/jimmunol.0803832. Epub 2009 Sep 4.


Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury.

Scotton CJ, Krupiczojc MA, Königshoff M, Mercer PF, Lee YC, Kaminski N, Morser J, Post JM, Maher TM, Nicholson AG, Moffatt JD, Laurent GJ, Derian CK, Eickelberg O, Chambers RC.

J Clin Invest. 2009 Sep;119(9):2550-63. doi: 10.1172/JCI33288. Epub 2009 Aug 3.


The contribution of Ca2+ signaling and Ca2+ sensitivity to the regulation of airway smooth muscle contraction is different in rats and mice.

Bai Y, Sanderson MJ.

Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L947-58. doi: 10.1152/ajplung.90288.2008. Epub 2009 Apr 3.


Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q).

Xu MY, Porte J, Knox AJ, Weinreb PH, Maher TM, Violette SM, McAnulty RJ, Sheppard D, Jenkins G.

Am J Pathol. 2009 Apr;174(4):1264-79. doi: 10.2353/ajpath.2009.080160. Epub 2009 Jan 15.


Mice that lack activity of alphavbeta6- and alphavbeta8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice.

Aluwihare P, Mu Z, Zhao Z, Yu D, Weinreb PH, Horan GS, Violette SM, Munger JS.

J Cell Sci. 2009 Jan 15;122(Pt 2):227-32. doi: 10.1242/jcs.035246.


Novel regulation of vascular endothelial growth factor-A (VEGF-A) by transforming growth factor (beta)1: requirement for Smads, (beta)-CATENIN, AND GSK3(beta).

Clifford RL, Deacon K, Knox AJ.

J Biol Chem. 2008 Dec 19;283(51):35337-53. doi: 10.1074/jbc.M803342200. Epub 2008 Oct 23.


Mast cells promote airway smooth muscle cell differentiation via autocrine up-regulation of TGF-beta 1.

Woodman L, Siddiqui S, Cruse G, Sutcliffe A, Saunders R, Kaur D, Bradding P, Brightling C.

J Immunol. 2008 Oct 1;181(7):5001-7.


Tryptase activates TGFbeta in human airway smooth muscle cells via direct proteolysis.

Tatler AL, Porte J, Knox A, Jenkins G, Pang L.

Biochem Biophys Res Commun. 2008 May 30;370(2):239-42. doi: 10.1016/j.bbrc.2008.03.064. Epub 2008 Mar 24.


Transforming growth factor beta 1 increases fibronectin deposition through integrin receptor alpha 5 beta 1 on human airway smooth muscle.

Moir LM, Burgess JK, Black JL.

J Allergy Clin Immunol. 2008 Apr;121(4):1034-9.e4. doi: 10.1016/j.jaci.2007.12.1159. Epub 2008 Feb 4.


Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix.

Wipff PJ, Rifkin DB, Meister JJ, Hinz B.

J Cell Biol. 2007 Dec 17;179(6):1311-23.


Impact of lung remodelling on respiratory mechanics in a model of severe allergic inflammation.

Silva PL, Passaro CP, Cagido VR, Bozza M, Dolhnikoff M, Negri EM, Morales MM, Capelozzi VL, Zin WA, Rocco PR.

Respir Physiol Neurobiol. 2008 Feb 29;160(3):239-48. Epub 2007 Oct 25.


Absence of integrin-mediated TGFbeta1 activation in vivo recapitulates the phenotype of TGFbeta1-null mice.

Yang Z, Mu Z, Dabovic B, Jurukovski V, Yu D, Sung J, Xiong X, Munger JS.

J Cell Biol. 2007 Mar 12;176(6):787-93.


Expression and activation of TGF-beta isoforms in acute allergen-induced remodelling in asthma.

Torrego A, Hew M, Oates T, Sukkar M, Fan Chung K.

Thorax. 2007 Apr;62(4):307-13. Epub 2007 Jan 24.


Small airway changes in healthy and ovalbumin-treated mice during quasi-static lung inflation.

Sera T, Uesugi K, Himeno R, Yagi N.

Respir Physiol Neurobiol. 2007 Jun 15;156(3):304-11. Epub 2006 Nov 21.

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