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Results: 1 to 20 of 60

1.

Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities.

Chiorazzi N, Ferrarini M.

Blood. 2011 Feb 10;117(6):1781-91. doi: 10.1182/blood-2010-07-155663. Epub 2010 Dec 9. Review.

PMID:
21148333
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Functional characterization of FLT3 receptor signaling deregulation in acute myeloid leukemia by single cell network profiling (SCNP).

Rosen DB, Minden MD, Kornblau SM, Cohen A, Gayko U, Putta S, Woronicz J, Evensen E, Fantl WJ, Cesano A.

PLoS One. 2010 Oct 27;5(10):e13543. doi: 10.1371/journal.pone.0013543.

PMID:
21048955
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Distinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and PI3kinase response profiles in human acute myelogenous leukemia.

Rosen DB, Putta S, Covey T, Huang YW, Nolan GP, Cesano A, Minden MD, Fantl WJ.

PLoS One. 2010 Aug 25;5(8):e12405. doi: 10.1371/journal.pone.0012405.

PMID:
20811632
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression.

Irish JM, Myklebust JH, Alizadeh AA, Houot R, Sharman JP, Czerwinski DK, Nolan GP, Levy R.

Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):12747-54. doi: 10.1073/pnas.1002057107. Epub 2010 Jun 11.

PMID:
20543139
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Dynamic single-cell network profiles in acute myelogenous leukemia are associated with patient response to standard induction therapy.

Kornblau SM, Minden MD, Rosen DB, Putta S, Cohen A, Covey T, Spellmeyer DC, Fantl WJ, Gayko U, Cesano A.

Clin Cancer Res. 2010 Jul 15;16(14):3721-33. doi: 10.1158/1078-0432.CCR-10-0093. Epub 2010 Jun 4.

PMID:
20525753
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma.

Davis RE, Ngo VN, Lenz G, Tolar P, Young RM, Romesser PB, Kohlhammer H, Lamy L, Zhao H, Yang Y, Xu W, Shaffer AL, Wright G, Xiao W, Powell J, Jiang JK, Thomas CJ, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Johnson NA, Rimsza LM, Campo E, Jaffe ES, Wilson WH, Delabie J, Smeland EB, Fisher RI, Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Pierce SK, Staudt LM.

Nature. 2010 Jan 7;463(7277):88-92. doi: 10.1038/nature08638.

PMID:
20054396
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Correlation between ZAP-70, phospho-ZAP-70, and phospho-Syk expression in leukemic cells from patients with CLL.

Kaplan D, Meyerson HJ, Li X, Drasny C, Liu F, Costaldi M, Barr P, Lazarus HM.

Cytometry B Clin Cytom. 2010 Mar;78(2):115-22. doi: 10.1002/cyto.b.20506.

PMID:
20014315
[PubMed - indexed for MEDLINE]
Free Article
8.

Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia.

Friedberg JW, Sharman J, Sweetenham J, Johnston PB, Vose JM, Lacasce A, Schaefer-Cutillo J, De Vos S, Sinha R, Leonard JP, Cripe LD, Gregory SA, Sterba MP, Lowe AM, Levy R, Shipp MA.

Blood. 2010 Apr 1;115(13):2578-85. doi: 10.1182/blood-2009-08-236471. Epub 2009 Nov 17.

PMID:
19965662
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Single-cell STAT5 signal transduction profiling in normal and leukemic stem and progenitor cell populations reveals highly distinct cytokine responses.

Han L, Wierenga AT, Rozenveld-Geugien M, van de Lande K, Vellenga E, Schuringa JJ.

PLoS One. 2009 Nov 24;4(11):e7989. doi: 10.1371/journal.pone.0007989.

PMID:
19956772
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5.

Xiao W, Hong H, Kawakami Y, Kato Y, Wu D, Yasudo H, Kimura A, Kubagawa H, Bertoli LF, Davis RS, Chau LA, Madrenas J, Hsia CC, Xenocostas A, Kipps TJ, Hennighausen L, Iwama A, Nakauchi H, Kawakami T.

Cancer Cell. 2009 Aug 4;16(2):161-71. doi: 10.1016/j.ccr.2009.05.018.

PMID:
19647226
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Spleen tyrosine kinase is overexpressed and represents a potential therapeutic target in chronic lymphocytic leukemia.

Buchner M, Fuchs S, Prinz G, Pfeifer D, Bartholomé K, Burger M, Chevalier N, Vallat L, Timmer J, Gribben JG, Jumaa H, Veelken H, Dierks C, Zirlik K.

Cancer Res. 2009 Jul 1;69(13):5424-32. doi: 10.1158/0008-5472.CAN-08-4252. Epub 2009 Jun 23.

PMID:
19549911
[PubMed - indexed for MEDLINE]
Free Article
12.

De novo deletion 17p13.1 chronic lymphocytic leukemia shows significant clinical heterogeneity: the M. D. Anderson and Mayo Clinic experience.

Tam CS, Shanafelt TD, Wierda WG, Abruzzo LV, Van Dyke DL, O'Brien S, Ferrajoli A, Lerner SA, Lynn A, Kay NE, Keating MJ.

Blood. 2009 Jul 30;114(5):957-64. doi: 10.1182/blood-2009-03-210591. Epub 2009 May 4.

PMID:
19414856
[PubMed - indexed for MEDLINE]
Free Article
13.

Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells.

Gobessi S, Laurenti L, Longo PG, Carsetti L, Berno V, Sica S, Leone G, Efremov DG.

Leukemia. 2009 Apr;23(4):686-97. doi: 10.1038/leu.2008.346. Epub 2008 Dec 18.

PMID:
19092849
[PubMed - indexed for MEDLINE]
14.

Microenvironmental influences in chronic lymphocytic leukaemia: the role of antigen stimulation.

Ghia P, Chiorazzi N, Stamatopoulos K.

J Intern Med. 2008 Dec;264(6):549-62. doi: 10.1111/j.1365-2796.2008.02030.x. Review.

PMID:
19017179
[PubMed - indexed for MEDLINE]
15.

Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates.

Kotecha N, Flores NJ, Irish JM, Simonds EF, Sakai DS, Archambeault S, Diaz-Flores E, Coram M, Shannon KM, Nolan GP, Loh ML.

Cancer Cell. 2008 Oct 7;14(4):335-43. doi: 10.1016/j.ccr.2008.08.014.

PMID:
18835035
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia.

Rassenti LZ, Jain S, Keating MJ, Wierda WG, Grever MR, Byrd JC, Kay NE, Brown JR, Gribben JG, Neuberg DS, He F, Greaves AW, Rai KR, Kipps TJ.

Blood. 2008 Sep 1;112(5):1923-30. doi: 10.1182/blood-2007-05-092882. Epub 2008 Jun 24.

PMID:
18577710
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

CLL and activated NF-kappaB: living partnership.

Hertlein E, Byrd JC.

Blood. 2008 May 1;111(9):4427. doi: 10.1182/blood-2008-02-137802. No abstract available.

PMID:
18441243
[PubMed]
Free Article
18.

The NF-kappaB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target.

Hewamana S, Alghazal S, Lin TT, Clement M, Jenkins C, Guzman ML, Jordan CT, Neelakantan S, Crooks PA, Burnett AK, Pratt G, Fegan C, Rowntree C, Brennan P, Pepper C.

Blood. 2008 May 1;111(9):4681-9. doi: 10.1182/blood-2007-11-125278. Epub 2008 Jan 28.

PMID:
18227347
[PubMed - indexed for MEDLINE]
Free Article
19.

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines.

Hallek M, Cheson BD, Catovsky D, Caligaris-Cappio F, Dighiero G, Döhner H, Hillmen P, Keating MJ, Montserrat E, Rai KR, Kipps TJ; International Workshop on Chronic Lymphocytic Leukemia.

Blood. 2008 Jun 15;111(12):5446-56. doi: 10.1182/blood-2007-06-093906. Epub 2008 Jan 23. Erratum in: Blood. 2008 Dec 15;112(13):5259.

PMID:
18216293
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

ZAP-70 enhances IgM signaling independent of its kinase activity in chronic lymphocytic leukemia.

Chen L, Huynh L, Apgar J, Tang L, Rassenti L, Weiss A, Kipps TJ.

Blood. 2008 Mar 1;111(5):2685-92. Epub 2007 Nov 29.

PMID:
18048647
[PubMed - indexed for MEDLINE]
Free PMC Article

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