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Studies of HIV-1 latency in an ex vivo model that uses primary central memory T cells.

Bosque A, Planelles V.

Methods. 2011 Jan;53(1):54-61. doi: 10.1016/j.ymeth.2010.10.002. Epub 2010 Oct 21. Review.


HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals.

Trono D, Van Lint C, Rouzioux C, Verdin E, Barré-Sinoussi F, Chun TW, Chomont N.

Science. 2010 Jul 9;329(5988):174-80. doi: 10.1126/science.1191047. Review.


Differentiation of effector CD4 T cell populations (*).

Zhu J, Yamane H, Paul WE.

Annu Rev Immunol. 2010;28:445-89. doi: 10.1146/annurev-immunol-030409-101212. Review.


Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation.

Yang HC, Xing S, Shan L, O'Connell K, Dinoso J, Shen A, Zhou Y, Shrum CK, Han Y, Liu JO, Zhang H, Margolick JB, Siliciano RF.

J Clin Invest. 2009 Nov;119(11):3473-86. doi: 10.1172/JCI39199. Epub 2009 Oct 1.


HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation.

Chomont N, El-Far M, Ancuta P, Trautmann L, Procopio FA, Yassine-Diab B, Boucher G, Boulassel MR, Ghattas G, Brenchley JM, Schacker TW, Hill BJ, Douek DC, Routy JP, Haddad EK, Sékaly RP.

Nat Med. 2009 Aug;15(8):893-900. doi: 10.1038/nm.1972. Epub 2009 Jun 21.


IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection.

Sereti I, Dunham RM, Spritzler J, Aga E, Proschan MA, Medvik K, Battaglia CA, Landay AL, Pahwa S, Fischl MA, Asmuth DM, Tenorio AR, Altman JD, Fox L, Moir S, Malaspina A, Morre M, Buffet R, Silvestri G, Lederman MM; ACTG 5214 Study Team.

Blood. 2009 Jun 18;113(25):6304-14. doi: 10.1182/blood-2008-10-186601. Epub 2009 Apr 20.


The challenge of finding a cure for HIV infection.

Richman DD, Margolis DM, Delaney M, Greene WC, Hazuda D, Pomerantz RJ.

Science. 2009 Mar 6;323(5919):1304-7. doi: 10.1126/science.1165706. Review.


Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid.

Archin NM, Espeseth A, Parker D, Cheema M, Hazuda D, Margolis DM.

AIDS Res Hum Retroviruses. 2009 Feb;25(2):207-12. doi: 10.1089/aid.2008.0191.


Determinants of the establishment of human immunodeficiency virus type 1 latency.

Duverger A, Jones J, May J, Bibollet-Ruche F, Wagner FA, Cron RQ, Kutsch O.

J Virol. 2009 Apr;83(7):3078-93. doi: 10.1128/JVI.02058-08. Epub 2009 Jan 14.


Homeostasis of naive and memory T cells.

Surh CD, Sprent J.

Immunity. 2008 Dec 19;29(6):848-62. doi: 10.1016/j.immuni.2008.11.002. Review.


Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells.

Bosque A, Planelles V.

Blood. 2009 Jan 1;113(1):58-65. doi: 10.1182/blood-2008-07-168393. Epub 2008 Oct 10.


Viral reservoirs, residual viremia, and the potential of highly active antiretroviral therapy to eradicate HIV infection.

Shen L, Siliciano RF.

J Allergy Clin Immunol. 2008 Jul;122(1):22-8. doi: 10.1016/j.jaci.2008.05.033. Review.


Cytokines and T-cell homeostasis.

Boyman O, Purton JF, Surh CD, Sprent J.

Curr Opin Immunol. 2007 Jun;19(3):320-6. Epub 2007 Apr 12. Review.


HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT.

Andersen JL, DeHart JL, Zimmerman ES, Ardon O, Kim B, Jacquot G, Benichou S, Planelles V.

PLoS Pathog. 2006 Dec;2(12):e127.


IL-7 is a potent and proviral strain-specific inducer of latent HIV-1 cellular reservoirs of infected individuals on virally suppressive HAART.

Wang FX, Xu Y, Sullivan J, Souder E, Argyris EG, Acheampong EA, Fisher J, Sierra M, Thomson MM, Najera R, Frank I, Kulkosky J, Pomerantz RJ, Nunnari G.

J Clin Invest. 2005 Jan;115(1):128-37.


Interleukin-7 induces HIV type 1 outgrowth from peripheral resting CD4+ T cells.

Lehrman G, Ylisastigui L, Bosch RJ, Margolis DM.

J Acquir Immune Defic Syndr. 2004 Aug 15;36(5):1103-4. No abstract available.


Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells.

Seddon B, Tomlinson P, Zamoyska R.

Nat Immunol. 2003 Jul;4(7):680-6. Epub 2003 Jun 15.


Latency in human immunodeficiency virus type 1 infection: no easy answers.

Persaud D, Zhou Y, Siliciano JM, Siliciano RF.

J Virol. 2003 Feb;77(3):1659-65. Review. No abstract available.


T cell dynamics in HIV-1 infection.

Douek DC, Picker LJ, Koup RA.

Annu Rev Immunol. 2003;21:265-304. Epub 2001 Dec 19. Review.

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