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Results: 1 to 20 of 24

1.

The patterns and dynamics of genomic instability in metastatic pancreatic cancer.

Campbell PJ, Yachida S, Mudie LJ, Stephens PJ, Pleasance ED, Stebbings LA, Morsberger LA, Latimer C, McLaren S, Lin ML, McBride DJ, Varela I, Nik-Zainal SA, Leroy C, Jia M, Menzies A, Butler AP, Teague JW, Griffin CA, Burton J, Swerdlow H, Quail MA, Stratton MR, Iacobuzio-Donahue C, Futreal PA.

Nature. 2010 Oct 28;467(7319):1109-13. doi: 10.1038/nature09460.

PMID:
20981101
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Accumulation of driver and passenger mutations during tumor progression.

Bozic I, Antal T, Ohtsuki H, Carter H, Kim D, Chen S, Karchin R, Kinzler KW, Vogelstein B, Nowak MA.

Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18545-50. doi: 10.1073/pnas.1010978107. Epub 2010 Sep 27.

PMID:
20876136
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma.

Cooke SL, Ng CK, Melnyk N, Garcia MJ, Hardcastle T, Temple J, Langdon S, Huntsman D, Brenton JD.

Oncogene. 2010 Sep 2;29(35):4905-13. doi: 10.1038/onc.2010.245. Epub 2010 Jun 28.

PMID:
20581869
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Genome remodelling in a basal-like breast cancer metastasis and xenograft.

Ding L, Ellis MJ, Li S, Larson DE, Chen K, Wallis JW, Harris CC, McLellan MD, Fulton RS, Fulton LL, Abbott RM, Hoog J, Dooling DJ, Koboldt DC, Schmidt H, Kalicki J, Zhang Q, Chen L, Lin L, Wendl MC, McMichael JF, Magrini VJ, Cook L, McGrath SD, Vickery TL, Appelbaum E, Deschryver K, Davies S, Guintoli T, Lin L, Crowder R, Tao Y, Snider JE, Smith SM, Dukes AF, Sanderson GE, Pohl CS, Delehaunty KD, Fronick CC, Pape KA, Reed JS, Robinson JS, Hodges JS, Schierding W, Dees ND, Shen D, Locke DP, Wiechert ME, Eldred JM, Peck JB, Oberkfell BJ, Lolofie JT, Du F, Hawkins AE, O'Laughlin MD, Bernard KE, Cunningham M, Elliott G, Mason MD, Thompson DM Jr, Ivanovich JL, Goodfellow PJ, Perou CM, Weinstock GM, Aft R, Watson M, Ley TJ, Wilson RK, Mardis ER.

Nature. 2010 Apr 15;464(7291):999-1005. doi: 10.1038/nature08989.

PMID:
20393555
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Non-melanoma skin cancer.

Madan V, Lear JT, Szeimies RM.

Lancet. 2010 Feb 20;375(9715):673-85. doi: 10.1016/S0140-6736(09)61196-X.

PMID:
20171403
[PubMed - indexed for MEDLINE]
6.

Copy neutral loss of heterozygosity: a novel chromosomal lesion in myeloid malignancies.

O'Keefe C, McDevitt MA, Maciejewski JP.

Blood. 2010 Apr 8;115(14):2731-9. doi: 10.1182/blood-2009-10-201848. Epub 2010 Jan 27. Review.

PMID:
20107230
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A comprehensive catalogue of somatic mutations from a human cancer genome.

Pleasance ED, Cheetham RK, Stephens PJ, McBride DJ, Humphray SJ, Greenman CD, Varela I, Lin ML, Ordóñez GR, Bignell GR, Ye K, Alipaz J, Bauer MJ, Beare D, Butler A, Carter RJ, Chen L, Cox AJ, Edkins S, Kokko-Gonzales PI, Gormley NA, Grocock RJ, Haudenschild CD, Hims MM, James T, Jia M, Kingsbury Z, Leroy C, Marshall J, Menzies A, Mudie LJ, Ning Z, Royce T, Schulz-Trieglaff OB, Spiridou A, Stebbings LA, Szajkowski L, Teague J, Williamson D, Chin L, Ross MT, Campbell PJ, Bentley DR, Futreal PA, Stratton MR.

Nature. 2010 Jan 14;463(7278):191-6. doi: 10.1038/nature08658. Epub 2009 Dec 16.

PMID:
20016485
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer.

Forbes SA, Tang G, Bindal N, Bamford S, Dawson E, Cole C, Kok CY, Jia M, Ewing R, Menzies A, Teague JW, Stratton MR, Futreal PA.

Nucleic Acids Res. 2010 Jan;38(Database issue):D652-7. doi: 10.1093/nar/gkp995. Epub 2009 Nov 11.

PMID:
19906727
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Uniparental disomy in cancer.

Tuna M, Knuutila S, Mills GB.

Trends Mol Med. 2009 Mar;15(3):120-8. doi: 10.1016/j.molmed.2009.01.005. Epub 2009 Feb 25. Review.

PMID:
19246245
[PubMed - indexed for MEDLINE]
10.

ATR: an essential regulator of genome integrity.

Cimprich KA, Cortez D.

Nat Rev Mol Cell Biol. 2008 Aug;9(8):616-27. doi: 10.1038/nrm2450. Epub 2008 Jul 2. Review.

PMID:
18594563
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases.

Lefort K, Mandinova A, Ostano P, Kolev V, Calpini V, Kolfschoten I, Devgan V, Lieb J, Raffoul W, Hohl D, Neel V, Garlick J, Chiorino G, Dotto GP.

Genes Dev. 2007 Mar 1;21(5):562-77.

PMID:
17344417
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome.

Olive KP, Tuveson DA, Ruhe ZC, Yin B, Willis NA, Bronson RT, Crowley D, Jacks T.

Cell. 2004 Dec 17;119(6):847-60.

PMID:
15607980
[PubMed - indexed for MEDLINE]
Free Article
13.

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.

Weng AP, Ferrando AA, Lee W, Morris JP 4th, Silverman LB, Sanchez-Irizarry C, Blacklow SC, Look AT, Aster JC.

Science. 2004 Oct 8;306(5694):269-71.

PMID:
15472075
[PubMed - indexed for MEDLINE]
Free Article
14.

Progression model for pancreatic cancer.

Hruban RH, Goggins M, Parsons J, Kern SE.

Clin Cancer Res. 2000 Aug;6(8):2969-72. Review. No abstract available.

PMID:
10955772
[PubMed - indexed for MEDLINE]
Free Article
15.

The scientific basis of skin cancer.

Leffell DJ.

J Am Acad Dermatol. 2000 Jan;42(1 Pt 2):18-22. Review.

PMID:
10607352
[PubMed - indexed for MEDLINE]
16.

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis.

Chin L, Artandi SE, Shen Q, Tam A, Lee SL, Gottlieb GJ, Greider CW, DePinho RA.

Cell. 1999 May 14;97(4):527-38.

PMID:
10338216
[PubMed - indexed for MEDLINE]
Free Article
17.

Benign clonal keratinocyte patches with p53 mutations show no genetic link to synchronous squamous cell precancer or cancer in human skin.

Ren ZP, Ahmadian A, Pontén F, Nistér M, Berg C, Lundeberg J, Uhlén M, Pontén J.

Am J Pathol. 1997 May;150(5):1791-803.

PMID:
9137102
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Frequent clones of p53-mutated keratinocytes in normal human skin.

Jonason AS, Kunala S, Price GJ, Restifo RJ, Spinelli HM, Persing JA, Leffell DJ, Tarone RE, Brash DE.

Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):14025-9.

PMID:
8943054
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

p53 and E2F-1 cooperate to mediate apoptosis.

Wu X, Levine AJ.

Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3602-6.

PMID:
8170954
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Sunburn and p53 in the onset of skin cancer.

Ziegler A, Jonason AS, Leffell DJ, Simon JA, Sharma HW, Kimmelman J, Remington L, Jacks T, Brash DE.

Nature. 1994 Dec 22-29;372(6508):773-6.

PMID:
7997263
[PubMed - indexed for MEDLINE]

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