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References for PMC Articles for PubMed (Select 21980284)


Cholesterol is not an essential source of nutrition for Mycobacterium tuberculosis during infection.

Yang X, Gao J, Smith I, Dubnau E, Sampson NS.

J Bacteriol. 2011 Mar;193(6):1473-6. doi: 10.1128/JB.01210-10. Epub 2011 Jan 21.


Genome-scale identification of resistance functions in Pseudomonas aeruginosa using Tn-seq.

Gallagher LA, Shendure J, Manoil C.

MBio. 2011 Jan 18;2(1):e00315-10. doi: 10.1128/mBio.00315-10.


Functional redundancy of steroid C26-monooxygenase activity in Mycobacterium tuberculosis revealed by biochemical and genetic analyses.

Johnston JB, Ouellet H, Ortiz de Montellano PR.

J Biol Chem. 2010 Nov 19;285(47):36352-60. doi: 10.1074/jbc.M110.161117. Epub 2010 Sep 15.


Mycobacterium tuberculosis wears what it eats.

Russell DG, VanderVen BC, Lee W, Abramovitch RB, Kim MJ, Homolka S, Niemann S, Rohde KH.

Cell Host Microbe. 2010 Jul 22;8(1):68-76. doi: 10.1016/j.chom.2010.06.002. Review.


Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one.

Ouellet H, Guan S, Johnston JB, Chow ED, Kells PM, Burlingame AL, Cox JS, Podust LM, de Montellano PR.

Mol Microbiol. 2010 Aug;77(3):730-42. doi: 10.1111/j.1365-2958.2010.07243.x. Epub 2010 Jun 10.


Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection.

Marrero J, Rhee KY, Schnappinger D, Pethe K, Ehrt S.

Proc Natl Acad Sci U S A. 2010 May 25;107(21):9819-24. doi: 10.1073/pnas.1000715107. Epub 2010 May 3.


3-Ketosteroid 9alpha-hydroxylase is an essential factor in the pathogenesis of Mycobacterium tuberculosis.

Hu Y, van der Geize R, Besra GS, Gurcha SS, Liu A, Rohde M, Singh M, Coates A.

Mol Microbiol. 2010 Jan;75(1):107-21. doi: 10.1111/j.1365-2958.2009.06957.x. Epub 2009 Nov 10.


Mycobacterial cytochrome p450 125 (cyp125) catalyzes the terminal hydroxylation of c27 steroids.

Capyk JK, Kalscheuer R, Stewart GR, Liu J, Kwon H, Zhao R, Okamoto S, Jacobs WR Jr, Eltis LD, Mohn WW.

J Biol Chem. 2009 Dec 18;284(51):35534-42. doi: 10.1074/jbc.M109.072132. Epub .


Cytochrome P450 125 (CYP125) catalyses C26-hydroxylation to initiate sterol side-chain degradation in Rhodococcus jostii RHA1.

Rosłoniec KZ, Wilbrink MH, Capyk JK, Mohn WW, Ostendorf M, van der Geize R, Dijkhuizen L, Eltis LD.

Mol Microbiol. 2009 Dec;74(5):1031-43. doi: 10.1111/j.1365-2958.2009.06915.x. Epub 2009 Oct 15.


Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants.

Langridge GC, Phan MD, Turner DJ, Perkins TT, Parts L, Haase J, Charles I, Maskell DJ, Peters SE, Dougan G, Wain J, Parkhill J, Turner AK.

Genome Res. 2009 Dec;19(12):2308-16. doi: 10.1101/gr.097097.109. Epub 2009 Oct 13.


A thiolase of Mycobacterium tuberculosis is required for virulence and production of androstenedione and androstadienedione from cholesterol.

Nesbitt NM, Yang X, Fontán P, Kolesnikova I, Smith I, Sampson NS, Dubnau E.

Infect Immun. 2010 Jan;78(1):275-82. doi: 10.1128/IAI.00893-09. Epub 2009 Oct 12.


Tracking insertion mutants within libraries by deep sequencing and a genome-wide screen for Haemophilus genes required in the lung.

Gawronski JD, Wong SM, Giannoukos G, Ward DV, Akerley BJ.

Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16422-7. doi: 10.1073/pnas.0906627106. Epub 2009 Sep 4.


Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms.

van Opijnen T, Bodi KL, Camilli A.

Nat Methods. 2009 Oct;6(10):767-72. doi: 10.1038/nmeth.1377. Epub 2009 Sep 20.


Role of the transcriptional regulator RamB (Rv0465c) in the control of the glyoxylate cycle in Mycobacterium tuberculosis.

Micklinghoff JC, Breitinger KJ, Schmidt M, Geffers R, Eikmanns BJ, Bange FC.

J Bacteriol. 2009 Dec;191(23):7260-9. doi: 10.1128/JB.01009-09. Epub 2009 Sep 18.


Identifying genetic determinants needed to establish a human gut symbiont in its habitat.

Goodman AL, McNulty NP, Zhao Y, Leip D, Mitra RD, Lozupone CA, Knight R, Gordon JI.

Cell Host Microbe. 2009 Sep 17;6(3):279-89. doi: 10.1016/j.chom.2009.08.003.


igr Genes and Mycobacterium tuberculosis cholesterol metabolism.

Chang JC, Miner MD, Pandey AK, Gill WP, Harik NS, Sassetti CM, Sherman DR.

J Bacteriol. 2009 Aug;191(16):5232-9. doi: 10.1128/JB.00452-09. Epub 2009 Jun 19.


Cholesterol metabolism increases the metabolic pool of propionate in Mycobacterium tuberculosis.

Yang X, Nesbitt NM, Dubnau E, Smith I, Sampson NS.

Biochemistry. 2009 May 12;48(18):3819-21. doi: 10.1021/bi9005418.


Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis.

Yam KC, D'Angelo I, Kalscheuer R, Zhu H, Wang JX, Snieckus V, Ly LH, Converse PJ, Jacobs WR Jr, Strynadka N, Eltis LD.

PLoS Pathog. 2009 Mar;5(3):e1000344. doi: 10.1371/journal.ppat.1000344. Epub 2009 Mar 20.


Mycobacterial persistence requires the utilization of host cholesterol.

Pandey AK, Sassetti CM.

Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4376-80. doi: 10.1073/pnas.0711159105. Epub 2008 Mar 11. Erratum in: Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9130.


SOAP: short oligonucleotide alignment program.

Li R, Li Y, Kristiansen K, Wang J.

Bioinformatics. 2008 Mar 1;24(5):713-4. doi: 10.1093/bioinformatics/btn025. Epub 2008 Jan 28.

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