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Items: 1 to 20 of 110

1.

Tyrosine phosphorylation-dependent activation of TRPC6 regulated by PLC-γ1 and nephrin: effect of mutations associated with focal segmental glomerulosclerosis.

Kanda S, Harita Y, Shibagaki Y, Sekine T, Igarashi T, Inoue T, Hattori S.

Mol Biol Cell. 2011 Jun 1;22(11):1824-35. doi: 10.1091/mbc.E10-12-0929. Epub 2011 Apr 6.

2.

Common variation in GPC5 is associated with acquired nephrotic syndrome.

Okamoto K, Tokunaga K, Doi K, Fujita T, Suzuki H, Katoh T, Watanabe T, Nishida N, Mabuchi A, Takahashi A, Kubo M, Maeda S, Nakamura Y, Noiri E.

Nat Genet. 2011 May;43(5):459-63. doi: 10.1038/ng.792. Epub 2011 Mar 27.

PMID:
21441931
3.

TRPC6 enhances angiotensin II-induced albuminuria.

Eckel J, Lavin PJ, Finch EA, Mukerji N, Burch J, Gbadegesin R, Wu G, Bowling B, Byrd A, Hall G, Sparks M, Zhang ZS, Homstad A, Barisoni L, Birbaumer L, Rosenberg P, Winn MP.

J Am Soc Nephrol. 2011 Mar;22(3):526-35. doi: 10.1681/ASN.2010050522. Epub 2011 Jan 21.

4.

Potassium leakage from an active nerve fibre.

HODGKIN AL, HUXLEY AF.

Nature. 1946 Sep 14;158:376. No abstract available.

PMID:
21065150
5.

Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels.

Tian D, Jacobo SM, Billing D, Rozkalne A, Gage SD, Anagnostou T, Pavenstädt H, Hsu HH, Schlondorff J, Ramos A, Greka A.

Sci Signal. 2010 Oct 26;3(145):ra77. doi: 10.1126/scisignal.2001200. Erratum in: Sci Signal. 2010;3(147):er11. Pavenstaedt, Hermann [corrected to Pavenstädt, Hermann].

6.

Cytosolic Ca2+ buffers.

Schwaller B.

Cold Spring Harb Perspect Biol. 2010 Nov;2(11):a004051. doi: 10.1101/cshperspect.a004051. Epub 2010 Oct 13. Review.

7.

Podocyte-specific overexpression of wild type or mutant trpc6 in mice is sufficient to cause glomerular disease.

Krall P, Canales CP, Kairath P, Carmona-Mora P, Molina J, Carpio JD, Ruiz P, Mezzano SA, Li J, Wei C, Reiser J, Young JI, Walz K.

PLoS One. 2010 Sep 20;5(9):e12859. doi: 10.1371/journal.pone.0012859.

8.

The role of transient receptor potential cation channels in Ca2+ signaling.

Gees M, Colsoul B, Nilius B.

Cold Spring Harb Perspect Biol. 2010 Oct;2(10):a003962. doi: 10.1101/cshperspect.a003962. Epub 2010 Sep 22.

9.

TRPC6 channels and their binding partners in podocytes: role in glomerular filtration and pathophysiology.

Dryer SE, Reiser J.

Am J Physiol Renal Physiol. 2010 Oct;299(4):F689-701. doi: 10.1152/ajprenal.00298.2010. Epub 2010 Aug 4. Review.

10.

Activation of NFAT signaling in podocytes causes glomerulosclerosis.

Wang Y, Jarad G, Tripathi P, Pan M, Cunningham J, Martin DR, Liapis H, Miner JH, Chen F.

J Am Soc Nephrol. 2010 Oct;21(10):1657-66. doi: 10.1681/ASN.2009121253. Epub 2010 Jul 22.

11.

TRPC channels are necessary mediators of pathologic cardiac hypertrophy.

Wu X, Eder P, Chang B, Molkentin JD.

Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):7000-5. doi: 10.1073/pnas.1001825107. Epub 2010 Mar 29.

12.

The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure.

Guilluy C, Brégeon J, Toumaniantz G, Rolli-Derkinderen M, Retailleau K, Loufrani L, Henrion D, Scalbert E, Bril A, Torres RM, Offermanns S, Pacaud P, Loirand G.

Nat Med. 2010 Feb;16(2):183-90. doi: 10.1038/nm.2079. Epub 2010 Jan 24.

PMID:
20098430
13.

Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis.

Brown EJ, Schlöndorff JS, Becker DJ, Tsukaguchi H, Tonna SJ, Uscinski AL, Higgs HN, Henderson JM, Pollak MR.

Nat Genet. 2010 Jan;42(1):72-6. doi: 10.1038/ng.505. Epub 2009 Dec 20. Erratum in: Nat Genet. 2010 Apr;42(4):361. Tonna, Stephen J [added].

14.

A novel TRPC6 mutation that causes childhood FSGS.

Heeringa SF, Möller CC, Du J, Yue L, Hinkes B, Chernin G, Vlangos CN, Hoyer PF, Reiser J, Hildebrandt F.

PLoS One. 2009 Nov 10;4(11):e7771. doi: 10.1371/journal.pone.0007771.

15.

Experience-dependent structural synaptic plasticity in the mammalian brain.

Holtmaat A, Svoboda K.

Nat Rev Neurosci. 2009 Sep;10(9):647-58. doi: 10.1038/nrn2699. Review. Erratum in: Nat Rev Neurosci. 2009 Oct;10(10):759.

PMID:
19693029
16.

Functional analysis of promoter mutations in the ACTN4 and SYNPO genes in focal segmental glomerulosclerosis.

Dai S, Wang Z, Pan X, Wang W, Chen X, Ren H, Hao C, Han B, Chen N.

Nephrol Dial Transplant. 2010 Mar;25(3):824-35. doi: 10.1093/ndt/gfp394. Epub 2009 Aug 7.

17.

Essential role for TRPC5 in amygdala function and fear-related behavior.

Riccio A, Li Y, Moon J, Kim KS, Smith KS, Rudolph U, Gapon S, Yao GL, Tsvetkov E, Rodig SJ, Van't Veer A, Meloni EG, Carlezon WA Jr, Bolshakov VY, Clapham DE.

Cell. 2009 May 15;137(4):761-72. doi: 10.1016/j.cell.2009.03.039.

18.

Intracellular calcium strongly potentiates agonist-activated TRPC5 channels.

Blair NT, Kaczmarek JS, Clapham DE.

J Gen Physiol. 2009 May;133(5):525-46. doi: 10.1085/jgp.200810153.

19.

Cardiovascular implications of proteinuria: an indicator of chronic kidney disease.

Agrawal V, Marinescu V, Agarwal M, McCullough PA.

Nat Rev Cardiol. 2009 Apr;6(4):301-11. doi: 10.1038/nrcardio.2009.11. Review.

PMID:
19352334
20.

Flufenamic acid is a tool for investigating TRPC6-mediated calcium signalling in human conditionally immortalised podocytes and HEK293 cells.

Foster RR, Zadeh MA, Welsh GI, Satchell SC, Ye Y, Mathieson PW, Bates DO, Saleem MA.

Cell Calcium. 2009 Apr;45(4):384-90. doi: 10.1016/j.ceca.2009.01.003. Epub 2009 Feb 20.

PMID:
19232718
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