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Results: 1 to 20 of 51

1.

GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models.

Lu X, Roberts E, Xia F, Sanchez-Alavez M, Liu T, Baldwin R, Wu S, Chang J, Wasterlain CG, Bartfai T.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15229-34. doi: 10.1073/pnas.1008986107. Epub 2010 Jul 26.

PMID:
20660766
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The endocannabinoid system tonically regulates inhibitory transmission and depresses the effect of ethanol in central amygdala.

Roberto M, Cruz M, Bajo M, Siggins GR, Parsons LH, Schweitzer P.

Neuropsychopharmacology. 2010 Aug;35(9):1962-72. doi: 10.1038/npp.2010.70. Epub 2010 May 12.

PMID:
20463657
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Corticotropin releasing factor-induced amygdala gamma-aminobutyric Acid release plays a key role in alcohol dependence.

Roberto M, Cruz MT, Gilpin NW, Sabino V, Schweitzer P, Bajo M, Cottone P, Madamba SG, Stouffer DG, Zorrilla EP, Koob GF, Siggins GR, Parsons LH.

Biol Psychiatry. 2010 May 1;67(9):831-9. doi: 10.1016/j.biopsych.2009.11.007. Epub 2010 Jan 8.

PMID:
20060104
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Increased intake of ethanol and dietary fat in galanin overexpressing mice.

Karatayev O, Baylan J, Leibowitz SF.

Alcohol. 2009 Dec;43(8):571-80. doi: 10.1016/j.alcohol.2009.09.025.

PMID:
20004335
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Galanin knockout mice show disturbances in ethanol consumption and expression of hypothalamic peptides that stimulate ethanol intake.

Karatayev O, Baylan J, Weed V, Chang S, Wynick D, Leibowitz SF.

Alcohol Clin Exp Res. 2010 Jan;34(1):72-80. doi: 10.1111/j.1530-0277.2009.01068.x. Epub 2009 Oct 23.

PMID:
19860804
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Bidirectional regulation of stress responses by galanin in mice: involvement of galanin receptor subtype 1.

Mitsukawa K, Lu X, Bartfai T.

Neuroscience. 2009 Jun 2;160(4):837-46. doi: 10.1016/j.neuroscience.2009.02.063. Epub 2009 Mar 9.

PMID:
19272414
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Presynaptic CRF1 receptors mediate the ethanol enhancement of GABAergic transmission in the mouse central amygdala.

Nie Z, Zorrilla EP, Madamba SG, Rice KC, Roberto M, Siggins GR.

ScientificWorldJournal. 2009 Jan 18;9:68-85. doi: 10.1100/tsw.2009.1.

PMID:
19151899
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mu-opioid receptors selectively regulate basal inhibitory transmission in the central amygdala: lack of ethanol interactions.

Kang-Park MH, Kieffer BL, Roberts AJ, Roberto M, Madamba SG, Siggins GR, Moore SD.

J Pharmacol Exp Ther. 2009 Jan;328(1):284-93. doi: 10.1124/jpet.108.140749. Epub 2008 Oct 14.

PMID:
18854491
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Phenotypic analysis of GalR2 knockout mice in anxiety- and depression-related behavioral tests.

Lu X, Ross B, Sanchez-Alavez M, Zorrilla EP, Bartfai T.

Neuropeptides. 2008 Aug;42(4):387-97. doi: 10.1016/j.npep.2008.04.009. Epub 2008 Jun 12.

PMID:
18554714
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Protein kinase C epsilon mediation of CRF- and ethanol-induced GABA release in central amygdala.

Bajo M, Cruz MT, Siggins GR, Messing R, Roberto M.

Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8410-5. doi: 10.1073/pnas.0802302105. Epub 2008 Jun 9.

PMID:
18541912
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Galanin alters GABAergic neurotransmission in the dorsal raphe nucleus.

Sharkey LM, Madamba SG, Siggins GR, Bartfai T.

Neurochem Res. 2008 Feb;33(2):285-91. Epub 2007 Nov 1.

PMID:
17973188
[PubMed - indexed for MEDLINE]
12.

The brain galanin receptors: targets for novel antidepressant drugs.

Lu X, Sharkey L, Bartfai T.

CNS Neurol Disord Drug Targets. 2007 Jun;6(3):183-92. Review.

PMID:
17511615
[PubMed - indexed for MEDLINE]
13.

Effect of ethanol on hypothalamic opioid peptides, enkephalin, and dynorphin: relationship with circulating triglycerides.

Chang GQ, Karatayev O, Ahsan R, Avena NM, Lee C, Lewis MJ, Hoebel BG, Leibowitz SF.

Alcohol Clin Exp Res. 2007 Feb;31(2):249-59.

PMID:
17250616
[PubMed - indexed for MEDLINE]
14.

Presynaptic delta opioid receptors regulate ethanol actions in central amygdala.

Kang-Park MH, Kieffer BL, Roberts AJ, Siggins GR, Moore SD.

J Pharmacol Exp Ther. 2007 Feb;320(2):917-25. Epub 2006 Nov 17.

PMID:
17114568
[PubMed - indexed for MEDLINE]
Free Article
15.

Galanin receptor antagonists : a potential novel pharmacological treatment for mood disorders.

Ogren SO, Kuteeva E, Hökfelt T, Kehr J.

CNS Drugs. 2006;20(8):633-54. Review.

PMID:
16863269
[PubMed - indexed for MEDLINE]
16.

Nociceptin/orphanin FQ presynaptically decreases GABAergic transmission and blocks the ethanol-induced increase of GABA release in central amygdala.

Roberto M, Siggins GR.

Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9715-20.

PMID:
16788074
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299.

Swanson CJ, Blackburn TP, Zhang X, Zheng K, Xu ZQ, Hökfelt T, Wolinsky TD, Konkel MJ, Chen H, Zhong H, Walker MW, Craig DA, Gerald CP, Branchek TA.

Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17489-94. Epub 2005 Nov 15. Erratum in: Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14978. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5632.

PMID:
16287967
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Galanin can attenuate opiate reinforcement and withdrawal.

Picciotto MR, Hawes JJ, Brunzell DH, Zachariou V.

Neuropeptides. 2005 Jun;39(3):313-5. Epub 2005 Jan 28. Review.

PMID:
15944028
[PubMed - indexed for MEDLINE]
19.

Distribution and differential regulation of galanin receptor subtypes in rat brain: effects of seizure activity.

Lu X, Mazarati A, Sanna P, Shinmei S, Bartfai T.

Neuropeptides. 2005 Jun;39(3):147-52. Epub 2005 Jan 26.

PMID:
15944003
[PubMed - indexed for MEDLINE]
20.

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