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Results: 1 to 20 of 145

1.

AMP-activated protein kinase: also regulated by ADP?

Hardie DG, Carling D, Gamblin SJ.

Trends Biochem Sci. 2011 Sep;36(9):470-7. doi: 10.1016/j.tibs.2011.06.004. Epub 2011 Jul 23. Review.

PMID:
21782450
[PubMed - indexed for MEDLINE]
2.

AMPK is a direct adenylate charge-regulated protein kinase.

Oakhill JS, Steel R, Chen ZP, Scott JW, Ling N, Tam S, Kemp BE.

Science. 2011 Jun 17;332(6036):1433-5. doi: 10.1126/science.1200094.

PMID:
21680840
[PubMed - indexed for MEDLINE]
Free Article
3.

Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis.

Mihaylova MM, Vasquez DS, Ravnskjaer K, Denechaud PD, Yu RT, Alvarez JG, Downes M, Evans RM, Montminy M, Shaw RJ.

Cell. 2011 May 13;145(4):607-21. doi: 10.1016/j.cell.2011.03.043.

PMID:
21565617
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice.

Li Y, Xu S, Mihaylova MM, Zheng B, Hou X, Jiang B, Park O, Luo Z, Lefai E, Shyy JY, Gao B, Wierzbicki M, Verbeuren TJ, Shaw RJ, Cohen RA, Zang M.

Cell Metab. 2011 Apr 6;13(4):376-88. doi: 10.1016/j.cmet.2011.03.009.

PMID:
21459323
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Structure of mammalian AMPK and its regulation by ADP.

Xiao B, Sanders MJ, Underwood E, Heath R, Mayer FV, Carmena D, Jing C, Walker PA, Eccleston JF, Haire LF, Saiu P, Howell SA, Aasland R, Martin SR, Carling D, Gamblin SJ.

Nature. 2011 Apr 14;472(7342):230-3. doi: 10.1038/nature09932. Epub 2011 Mar 13.

PMID:
21399626
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.

Kim J, Kundu M, Viollet B, Guan KL.

Nat Cell Biol. 2011 Feb;13(2):132-41. doi: 10.1038/ncb2152. Epub 2011 Jan 23.

PMID:
21258367
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy.

Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, Asara JM, Fitzpatrick J, Dillin A, Viollet B, Kundu M, Hansen M, Shaw RJ.

Science. 2011 Jan 28;331(6016):456-61. doi: 10.1126/science.1196371. Epub 2010 Dec 23.

PMID:
21205641
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

mTOR: from growth signal integration to cancer, diabetes and ageing.

Zoncu R, Efeyan A, Sabatini DM.

Nat Rev Mol Cell Biol. 2011 Jan;12(1):21-35. doi: 10.1038/nrm3025. Epub 2010 Dec 15. Review.

PMID:
21157483
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

β-Subunit myristoylation is the gatekeeper for initiating metabolic stress sensing by AMP-activated protein kinase (AMPK).

Oakhill JS, Chen ZP, Scott JW, Steel R, Castelli LA, Ling N, Macaulay SL, Kemp BE.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19237-41. doi: 10.1073/pnas.1009705107. Epub 2010 Oct 25.

PMID:
20974912
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The energetics of genome complexity.

Lane N, Martin W.

Nature. 2010 Oct 21;467(7318):929-34. doi: 10.1038/nature09486.

PMID:
20962839
[PubMed - indexed for MEDLINE]
11.

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance.

López M, Varela L, Vázquez MJ, Rodríguez-Cuenca S, González CR, Velagapudi VR, Morgan DA, Schoenmakers E, Agassandian K, Lage R, Martínez de Morentin PB, Tovar S, Nogueiras R, Carling D, Lelliott C, Gallego R, Oresic M, Chatterjee K, Saha AK, Rahmouni K, Diéguez C, Vidal-Puig A.

Nat Med. 2010 Sep;16(9):1001-8. doi: 10.1038/nm.2207. Epub 2010 Aug 29.

PMID:
20802499
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Hispidulin potently inhibits human glioblastoma multiforme cells through activation of AMP-activated protein kinase (AMPK).

Lin YC, Hung CM, Tsai JC, Lee JC, Chen YL, Wei CW, Kao JY, Way TD.

J Agric Food Chem. 2010 Sep 8;58(17):9511-7. doi: 10.1021/jf1019533.

PMID:
20698539
[PubMed - indexed for MEDLINE]
13.

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.

Foretz M, Hébrard S, Leclerc J, Zarrinpashneh E, Soty M, Mithieux G, Sakamoto K, Andreelli F, Viollet B.

J Clin Invest. 2010 Jul;120(7):2355-69. doi: 10.1172/JCI40671. Epub 2010 Jun 23.

PMID:
20577053
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Network organization of the human autophagy system.

Behrends C, Sowa ME, Gygi SP, Harper JW.

Nature. 2010 Jul 1;466(7302):68-76. doi: 10.1038/nature09204. Epub 2010 Jun 20.

PMID:
20562859
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase.

Mankouri J, Tedbury PR, Gretton S, Hughes ME, Griffin SD, Dallas ML, Green KA, Hardie DG, Peers C, Harris M.

Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11549-54. doi: 10.1073/pnas.0912426107. Epub 2010 Jun 7.

PMID:
20534540
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Use of cells expressing gamma subunit variants to identify diverse mechanisms of AMPK activation.

Hawley SA, Ross FA, Chevtzoff C, Green KA, Evans A, Fogarty S, Towler MC, Brown LJ, Ogunbayo OA, Evans AM, Hardie DG.

Cell Metab. 2010 Jun 9;11(6):554-65. doi: 10.1016/j.cmet.2010.04.001.

PMID:
20519126
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle.

Cantó C, Jiang LQ, Deshmukh AS, Mataki C, Coste A, Lagouge M, Zierath JR, Auwerx J.

Cell Metab. 2010 Mar 3;11(3):213-9. doi: 10.1016/j.cmet.2010.02.006.

PMID:
20197054
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase.

Stahmann N, Woods A, Spengler K, Heslegrave A, Bauer R, Krause S, Viollet B, Carling D, Heller R.

J Biol Chem. 2010 Apr 2;285(14):10638-52. doi: 10.1074/jbc.M110.108688. Epub 2010 Feb 3.

PMID:
20129920
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Autophagy in cellular growth control.

Wang RC, Levine B.

FEBS Lett. 2010 Apr 2;584(7):1417-26. doi: 10.1016/j.febslet.2010.01.009. Epub 2010 Jan 22. Review.

PMID:
20096689
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Calmodulin-dependent protein kinase kinase-beta activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP.

Fogarty S, Hawley SA, Green KA, Saner N, Mustard KJ, Hardie DG.

Biochem J. 2010 Jan 27;426(1):109-18. doi: 10.1042/BJ20091372.

PMID:
19958286
[PubMed - indexed for MEDLINE]
Free PMC Article

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