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Items: 1 to 20 of 89

1.

Subtypes of medulloblastoma have distinct developmental origins.

Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ.

Nature. 2010 Dec 23;468(7327):1095-9. doi: 10.1038/nature09587. Epub 2010 Dec 8.

2.

Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome.

Cho YJ, Tsherniak A, Tamayo P, Santagata S, Ligon A, Greulich H, Berhoukim R, Amani V, Goumnerova L, Eberhart CG, Lau CC, Olson JM, Gilbertson RJ, Gajjar A, Delattre O, Kool M, Ligon K, Meyerson M, Mesirov JP, Pomeroy SL.

J Clin Oncol. 2011 Apr 10;29(11):1424-30. doi: 10.1200/JCO.2010.28.5148. Epub 2010 Nov 22.

3.

Medulloblastoma comprises four distinct molecular variants.

Northcott PA, Korshunov A, Witt H, Hielscher T, Eberhart CG, Mack S, Bouffet E, Clifford SC, Hawkins CE, French P, Rutka JT, Pfister S, Taylor MD.

J Clin Oncol. 2011 Apr 10;29(11):1408-14. doi: 10.1200/JCO.2009.27.4324. Epub 2010 Sep 7.

4.

Cooperative and individualistic functions of the microRNAs in the miR-23a~27a~24-2 cluster and its implication in human diseases.

Chhabra R, Dubey R, Saini N.

Mol Cancer. 2010 Sep 3;9:232. doi: 10.1186/1476-4598-9-232. Review.

5.

MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence.

Venkataraman S, Alimova I, Fan R, Harris P, Foreman N, Vibhakar R.

PLoS One. 2010 Jun 21;5(6):e10748. doi: 10.1371/journal.pone.0010748.

6.

Signatures of microRNAs and selected microRNA target genes in human melanoma.

Philippidou D, Schmitt M, Moser D, Margue C, Nazarov PV, Muller A, Vallar L, Nashan D, Behrmann I, Kreis S.

Cancer Res. 2010 May 15;70(10):4163-73. doi: 10.1158/0008-5472.CAN-09-4512. Epub 2010 May 4.

7.

Malignant germ cell tumors display common microRNA profiles resulting in global changes in expression of messenger RNA targets.

Palmer RD, Murray MJ, Saini HK, van Dongen S, Abreu-Goodger C, Muralidhar B, Pett MR, Thornton CM, Nicholson JC, Enright AJ, Coleman N; Children's Cancer and Leukaemia Group.

Cancer Res. 2010 Apr 1;70(7):2911-23. doi: 10.1158/0008-5472.CAN-09-3301. Epub 2010 Mar 23.

8.

Cerebellar stem cells act as medulloblastoma-initiating cells in a mouse model and a neural stem cell signature characterizes a subset of human medulloblastomas.

Sutter R, Shakhova O, Bhagat H, Behesti H, Sutter C, Penkar S, Santuccione A, Bernays R, Heppner FL, Schüller U, Grotzer M, Moch H, Schraml P, Marino S.

Oncogene. 2010 Mar 25;29(12):1845-56. doi: 10.1038/onc.2009.472. Epub 2010 Jan 11.

PMID:
20062081
9.

Distinct microRNA alterations characterize high- and low-grade bladder cancer.

Catto JW, Miah S, Owen HC, Bryant H, Myers K, Dudziec E, Larré S, Milo M, Rehman I, Rosario DJ, Di Martino E, Knowles MA, Meuth M, Harris AL, Hamdy FC.

Cancer Res. 2009 Nov 1;69(21):8472-81. doi: 10.1158/0008-5472.CAN-09-0744. Epub 2009 Oct 20.

10.

Localization- and mutation-dependent microRNA (miRNA) expression signatures in gastrointestinal stromal tumours (GISTs), with a cluster of co-expressed miRNAs located at 14q32.31.

Haller F, von Heydebreck A, Zhang JD, Gunawan B, Langer C, Ramadori G, Wiemann S, Sahin O.

J Pathol. 2010 Jan;220(1):71-86. doi: 10.1002/path.2610.

PMID:
19768731
11.

Reelin affects chain-migration and differentiation of neural precursor cells.

Massalini S, Pellegatta S, Pisati F, Finocchiaro G, Farace MG, Ciafrè SA.

Mol Cell Neurosci. 2009 Dec;42(4):341-9. doi: 10.1016/j.mcn.2009.08.006. Epub 2009 Aug 19.

PMID:
19698788
12.

Effective adenovirus-mediated gene transfer into neural stem cells derived from human embryonic stem cells.

Bertram CM, Hawes SM, Egli S, Peh SL, Dottori M, Kees UR, Dallas PB.

Stem Cells Dev. 2010 Apr;19(4):569-78. doi: 10.1089/scd.2009.0183.

PMID:
19594361
13.

Clustered microRNAs' coordination in regulating protein-protein interaction network.

Yuan X, Liu C, Yang P, He S, Liao Q, Kang S, Zhao Y.

BMC Syst Biol. 2009 Jun 26;3:65. doi: 10.1186/1752-0509-3-65.

14.

MicroRNA and mRNA integrated analysis (MMIA): a web tool for examining biological functions of microRNA expression.

Nam S, Li M, Choi K, Balch C, Kim S, Nephew KP.

Nucleic Acids Res. 2009 Jul;37(Web Server issue):W356-62. doi: 10.1093/nar/gkp294. Epub 2009 May 6.

15.

The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors.

Northcott PA, Fernandez-L A, Hagan JP, Ellison DW, Grajkowska W, Gillespie Y, Grundy R, Van Meter T, Rutka JT, Croce CM, Kenney AM, Taylor MD.

Cancer Res. 2009 Apr 15;69(8):3249-55. doi: 10.1158/0008-5472.CAN-08-4710. Epub 2009 Apr 7.

16.

MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma.

Garzia L, Andolfo I, Cusanelli E, Marino N, Petrosino G, De Martino D, Esposito V, Galeone A, Navas L, Esposito S, Gargiulo S, Fattet S, Donofrio V, Cinalli G, Brunetti A, Vecchio LD, Northcott PA, Delattre O, Taylor MD, Iolascon A, Zollo M.

PLoS One. 2009;4(3):e4998. doi: 10.1371/journal.pone.0004998. Epub 2009 Mar 24.

17.

The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma.

Uziel T, Karginov FV, Xie S, Parker JS, Wang YD, Gajjar A, He L, Ellison D, Gilbertson RJ, Hannon G, Roussel MF.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2812-7. doi: 10.1073/pnas.0809579106. Epub 2009 Feb 5.

18.

Functional links between clustered microRNAs: suppression of cell-cycle inhibitors by microRNA clusters in gastric cancer.

Kim YK, Yu J, Han TS, Park SY, Namkoong B, Kim DH, Hur K, Yoo MW, Lee HJ, Yang HK, Kim VN.

Nucleic Acids Res. 2009 Apr;37(5):1672-81. doi: 10.1093/nar/gkp002. Epub 2009 Jan 19.

19.

Computational analysis of microRNA profiles and their target genes suggests significant involvement in breast cancer antiestrogen resistance.

Xin F, Li M, Balch C, Thomson M, Fan M, Liu Y, Hammond SM, Kim S, Nephew KP.

Bioinformatics. 2009 Feb 15;25(4):430-4. doi: 10.1093/bioinformatics/btn646. Epub 2008 Dec 17.

20.

Classic and desmoplastic medulloblastoma: complete case reports and characterizations of two new cell lines.

Holthouse DJ, Dallas PB, Ford J, Fabian V, Murch AR, Watson M, Wong G, Bertram C, Egli S, Baker DL, Kees UR.

Neuropathology. 2009 Aug;29(4):398-409. doi: 10.1111/j.1440-1789.2008.00989.x. Epub 2008 Dec 11.

PMID:
19077040
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