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Selective improvement of cognitive function in adult and aged APP/PS1 transgenic mice by continuous non-shock treadmill exercise.

Ke HC, Huang HJ, Liang KC, Hsieh-Li HM.

Brain Res. 2011 Jul 27;1403:1-11. doi: 10.1016/j.brainres.2011.05.056. Epub 2011 May 30.


Massive gliosis induced by interleukin-6 suppresses Abeta deposition in vivo: evidence against inflammation as a driving force for amyloid deposition.

Chakrabarty P, Jansen-West K, Beccard A, Ceballos-Diaz C, Levites Y, Verbeeck C, Zubair AC, Dickson D, Golde TE, Das P.

FASEB J. 2010 Feb;24(2):548-59. doi: 10.1096/fj.09-141754. Epub 2009 Oct 13.


Systemic inflammation and disease progression in Alzheimer disease.

Holmes C, Cunningham C, Zotova E, Woolford J, Dean C, Kerr S, Culliford D, Perry VH.

Neurology. 2009 Sep 8;73(10):768-74. doi: 10.1212/WNL.0b013e3181b6bb95.


Anti-inflammatory treatment in AD mice protects against neuronal pathology.

Choi JK, Jenkins BG, Carreras I, Kaymakcalan S, Cormier K, Kowall NW, Dedeoglu A.

Exp Neurol. 2010 Jun;223(2):377-84. doi: 10.1016/j.expneurol.2009.07.032. Epub 2009 Aug 10.


Lipopolysaccharide alters the blood-brain barrier transport of amyloid beta protein: a mechanism for inflammation in the progression of Alzheimer's disease.

Jaeger LB, Dohgu S, Sultana R, Lynch JL, Owen JB, Erickson MA, Shah GN, Price TO, Fleegal-Demotta MA, Butterfield DA, Banks WA.

Brain Behav Immun. 2009 May;23(4):507-17. doi: 10.1016/j.bbi.2009.01.017. Epub 2009 Feb 6. Erratum in: Brain Behav Immun. 2011 Nov;25(8):1737. Butterfiled, D Allan [corrected to Butterfield, D Allan].


Spinal interleukin-1beta in a mouse model of arthritis and joint pain.

Fiorentino PM, Tallents RH, Miller JN, Brouxhon SM, O'Banion MK, Puzas JE, Kyrkanides S.

Arthritis Rheum. 2008 Oct;58(10):3100-9. doi: 10.1002/art.23866.


Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease.

Cunningham C, Campion S, Lunnon K, Murray CL, Woods JF, Deacon RM, Rawlins JN, Perry VH.

Biol Psychiatry. 2009 Feb 15;65(4):304-12. doi: 10.1016/j.biopsych.2008.07.024. Epub 2008 Sep 18.


Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation.

Lee JW, Lee YK, Yuk DY, Choi DY, Ban SB, Oh KW, Hong JT.

J Neuroinflammation. 2008 Aug 29;5:37. doi: 10.1186/1742-2094-5-37.


Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice.

Hickman SE, Allison EK, El Khoury J.

J Neurosci. 2008 Aug 13;28(33):8354-60. doi: 10.1523/JNEUROSCI.0616-08.2008.


Alterations of the CD4(+), CD8 (+) T cell subsets, interleukins-1beta, IL-10, IL-17, tumor necrosis factor-alpha and soluble intercellular adhesion molecule-1 in rheumatoid arthritis and osteoarthritis: preliminary observations.

Hussein MR, Fathi NA, El-Din AM, Hassan HI, Abdullah F, Al-Hakeem E, Backer EA.

Pathol Oncol Res. 2008 Sep;14(3):321-8. doi: 10.1007/s12253-008-9016-1. Epub 2008 Apr 8.


Re: Inflammatory markers and the risk of Alzheimer disease: the Framingham Study.

Tobinick EL.

Neurology. 2008 Apr 1;70(14):1222-3; author reply 1223. doi: 10.1212/01.wnl.0000307660.86647.7b. No abstract available.


Differences of peripheral inflammatory markers between mild cognitive impairment and Alzheimer's disease.

Bermejo P, Martín-Aragón S, Benedí J, Susín C, Felici E, Gil P, Ribera JM, Villar AM.

Immunol Lett. 2008 May 15;117(2):198-202. doi: 10.1016/j.imlet.2008.02.002. Epub 2008 Mar 7.


Systemic immune aberrations in Alzheimer's disease patients.

Bonotis K, Krikki E, Holeva V, Aggouridaki C, Costa V, Baloyannis S.

J Neuroimmunol. 2008 Jan;193(1-2):183-7. Epub 2007 Nov 26.


Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology.

Shaftel SS, Kyrkanides S, Olschowka JA, Miller JN, Johnson RE, O'Banion MK.

J Clin Invest. 2007 Jun;117(6):1595-604.


Amelioration of pain and histopathologic joint abnormalities in the Col1-IL-1beta(XAT) mouse model of arthritis by intraarticular induction of mu-opioid receptor into the temporomandibular joint.

Kyrkanides S, Fiorentino PM, Miller JN, Gan Y, Lai YC, Shaftel SS, Puzas JE, Piancino MG, O'Banion MK, Tallents RH.

Arthritis Rheum. 2007 Jun;56(6):2038-48.


Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial.

ADAPT Research Group, Lyketsos CG, Breitner JC, Green RC, Martin BK, Meinert C, Piantadosi S, Sabbagh M.

Neurology. 2007 May 22;68(21):1800-8. Epub 2007 Apr 25.


Intraarticular induction of interleukin-1beta expression in the adult mouse, with resultant temporomandibular joint pathologic changes, dysfunction, and pain.

Lai YC, Shaftel SS, Miller JN, Tallents RH, Chang Y, Pinkert CA, Olschowka JA, Dickerson IM, Puzas JE, O'Banion MK, Kyrkanides S.

Arthritis Rheum. 2006 Apr;54(4):1184-97.


Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice.

Heneka MT, Sastre M, Dumitrescu-Ozimek L, Dewachter I, Walter J, Klockgether T, Van Leuven F.

J Neuroinflammation. 2005 Oct 7;2:22.

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