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Results: 1 to 20 of 55

1.

Synthesis and evaluation of indazole based analog sensitive Akt inhibitors.

Okuzumi T, Ducker GS, Zhang C, Aizenstein B, Hoffman R, Shokat KM.

Mol Biosyst. 2010 Aug;6(8):1389-402. doi: 10.1039/c003917a. Epub 2010 Jun 28.

PMID:
20582381
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Chemical genetic inhibition of Mps1 in stable human cell lines reveals novel aspects of Mps1 function in mitosis.

Sliedrecht T, Zhang C, Shokat KM, Kops GJ.

PLoS One. 2010 Apr 22;5(4):e10251. doi: 10.1371/journal.pone.0010251.

PMID:
20422024
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Par-4: a new activator of myosin phosphatase.

Vetterkind S, Lee E, Sundberg E, Poythress RH, Tao TC, Preuss U, Morgan KG.

Mol Biol Cell. 2010 Apr 1;21(7):1214-24. doi: 10.1091/mbc.E09-08-0711. Epub 2010 Feb 3.

PMID:
20130087
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Cardiac myosin is a substrate for zipper-interacting protein kinase (ZIPK).

Chang AN, Chen G, Gerard RD, Kamm KE, Stull JT.

J Biol Chem. 2010 Feb 19;285(8):5122-6. doi: 10.1074/jbc.C109.076489. Epub 2009 Dec 28.

PMID:
20038585
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Regulation of cellular protein phosphatase-1 (PP1) by phosphorylation of the CPI-17 family, C-kinase-activated PP1 inhibitors.

Eto M.

J Biol Chem. 2009 Dec 18;284(51):35273-7. doi: 10.1074/jbc.R109.059972. Epub . Review.

PMID:
19846560
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Ca2+-independent contraction of longitudinal ileal smooth muscle is potentiated by a zipper-interacting protein kinase pseudosubstrate peptide.

Ihara E, Moffat L, Borman MA, Amon JE, Walsh MP, MacDonald JA.

Am J Physiol Gastrointest Liver Physiol. 2009 Aug;297(2):G361-70. doi: 10.1152/ajpgi.00112.2009. Epub 2009 Jun 18.

PMID:
19541925
[PubMed - indexed for MEDLINE]
Free Article
7.

Structural insight into nucleotide recognition by human death-associated protein kinase.

McNamara LK, Watterson DM, Brunzelle JS.

Acta Crystallogr D Biol Crystallogr. 2009 Mar;65(Pt 3):241-8. doi: 10.1107/S0907444908043679. Epub 2009 Feb 20.

PMID:
19237746
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mitogen-activated protein kinase pathways contribute to hypercontractility and increased Ca2+ sensitization in murine experimental colitis.

Ihara E, Beck PL, Chappellaz M, Wong J, Medlicott SA, MacDonald JA.

Mol Pharmacol. 2009 May;75(5):1031-41. doi: 10.1124/mol.108.049858. Epub 2009 Feb 3.

PMID:
19190174
[PubMed - indexed for MEDLINE]
Free Article
9.

Protein structure homology modeling using SWISS-MODEL workspace.

Bordoli L, Kiefer F, Arnold K, Benkert P, Battey J, Schwede T.

Nat Protoc. 2009;4(1):1-13. doi: 10.1038/nprot.2008.197.

PMID:
19131951
[PubMed - indexed for MEDLINE]
10.

The pro-apoptotic protein Par-4 facilitates vascular contractility by cytoskeletal targeting of ZIPK.

Vetterkind S, Morgan KG.

J Cell Mol Med. 2009 May;13(5):887-95. doi: 10.1111/j.1582-4934.2008.00374.x. Epub 2008 May 24.

PMID:
18505470
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A highly sensitive technique to measure myosin regulatory light chain phosphorylation: the first quantification in renal arterioles.

Takeya K, Loutzenhiser K, Shiraishi M, Loutzenhiser R, Walsh MP.

Am J Physiol Renal Physiol. 2008 Jun;294(6):F1487-92. doi: 10.1152/ajprenal.00060.2008. Epub 2008 Apr 9.

PMID:
18400874
[PubMed - indexed for MEDLINE]
Free Article
12.

Design and use of analog-sensitive protein kinases.

Blethrow J, Zhang C, Shokat KM, Weiss EL.

Curr Protoc Mol Biol. 2004 May;Chapter 18:Unit 18.11. doi: 10.1002/0471142727.mb1811s66.

PMID:
18265343
[PubMed - indexed for MEDLINE]
13.

A quantitative analysis of kinase inhibitor selectivity.

Karaman MW, Herrgard S, Treiber DK, Gallant P, Atteridge CE, Campbell BT, Chan KW, Ciceri P, Davis MI, Edeen PT, Faraoni R, Floyd M, Hunt JP, Lockhart DJ, Milanov ZV, Morrison MJ, Pallares G, Patel HK, Pritchard S, Wodicka LM, Zarrinkar PP.

Nat Biotechnol. 2008 Jan;26(1):127-32. doi: 10.1038/nbt1358.

PMID:
18183025
[PubMed - indexed for MEDLINE]
14.

Myosin phosphatase target subunit: Many roles in cell function.

Matsumura F, Hartshorne DJ.

Biochem Biophys Res Commun. 2008 Apr 25;369(1):149-56. Epub 2007 Dec 26. Review.

PMID:
18155661
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Characterization of protein kinase pathways responsible for Ca2+ sensitization in rat ileal longitudinal smooth muscle.

Ihara E, Moffat L, Ostrander J, Walsh MP, MacDonald JA.

Am J Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G699-710. Epub 2007 Jul 26.

PMID:
17656444
[PubMed - indexed for MEDLINE]
Free Article
16.

The regulation of smooth muscle contractility by zipper-interacting protein kinase.

Ihara E, MacDonald JA.

Can J Physiol Pharmacol. 2007 Jan;85(1):79-87. Review.

PMID:
17487247
[PubMed - indexed for MEDLINE]
17.

Staurosporine inhibition of zipper-interacting protein kinase contractile effects in gastrointestinal smooth muscle.

Borman MA, MacDonald JA, Haystead TA.

Biochem Cell Biol. 2007 Feb;85(1):111-20.

PMID:
17464351
[PubMed - indexed for MEDLINE]
18.

Chemical genetics: where genetics and pharmacology meet.

Knight ZA, Shokat KM.

Cell. 2007 Feb 9;128(3):425-30.

PMID:
17289560
[PubMed - indexed for MEDLINE]
Free Article
19.

Identification of ChChd3 as a novel substrate of the cAMP-dependent protein kinase (PKA) using an analog-sensitive catalytic subunit.

Schauble S, King CC, Darshi M, Koller A, Shah K, Taylor SS.

J Biol Chem. 2007 May 18;282(20):14952-9. Epub 2007 Jan 22.

PMID:
17242405
[PubMed - indexed for MEDLINE]
Free Article
20.

Inhibition of zipper-interacting protein kinase function in smooth muscle by a myosin light chain kinase pseudosubstrate peptide.

Ihara E, Edwards E, Borman MA, Wilson DP, Walsh MP, MacDonald JA.

Am J Physiol Cell Physiol. 2007 May;292(5):C1951-9. Epub 2007 Jan 10.

PMID:
17215325
[PubMed - indexed for MEDLINE]
Free Article

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