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Results: 1 to 20 of 32

1.

Epigenetic inactivation of the miR-124-1 in haematological malignancies.

Wong KY, So CC, Loong F, Chung LP, Lam WW, Liang R, Li GK, Jin DY, Chim CS.

PLoS One. 2011 Apr 22;6(4):e19027. doi: 10.1371/journal.pone.0019027.

PMID:
21544199
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Widespread and tissue specific age-related DNA methylation changes in mice.

Maegawa S, Hinkal G, Kim HS, Shen L, Zhang L, Zhang J, Zhang N, Liang S, Donehower LA, Issa JP.

Genome Res. 2010 Mar;20(3):332-40. doi: 10.1101/gr.096826.109. Epub 2010 Jan 27.

PMID:
20107151
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Targeting DNA methylation.

Issa JP, Kantarjian HM.

Clin Cancer Res. 2009 Jun 15;15(12):3938-46. doi: 10.1158/1078-0432.CCR-08-2783. Epub 2009 Jun 9.

PMID:
19509174
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study.

Fenaux P, Mufti GJ, Hellstrom-Lindberg E, Santini V, Finelli C, Giagounidis A, Schoch R, Gattermann N, Sanz G, List A, Gore SD, Seymour JF, Bennett JM, Byrd J, Backstrom J, Zimmerman L, McKenzie D, Beach C, Silverman LR; International Vidaza High-Risk MDS Survival Study Group.

Lancet Oncol. 2009 Mar;10(3):223-32. doi: 10.1016/S1470-2045(09)70003-8. Epub 2009 Feb 21.

PMID:
19230772
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mechanisms of resistance to 5-aza-2'-deoxycytidine in human cancer cell lines.

Qin T, Jelinek J, Si J, Shu J, Issa JP.

Blood. 2009 Jan 15;113(3):659-67. doi: 10.1182/blood-2008-02-140038. Epub 2008 Oct 17.

PMID:
18931345
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Proposal for a new risk model in myelodysplastic syndrome that accounts for events not considered in the original International Prognostic Scoring System.

Kantarjian H, O'Brien S, Ravandi F, Cortes J, Shan J, Bennett JM, List A, Fenaux P, Sanz G, Issa JP, Freireich EJ, Garcia-Manero G.

Cancer. 2008 Sep 15;113(6):1351-61. doi: 10.1002/cncr.23697.

PMID:
18618511
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Aberrant CpG island methylation in acute myeloid leukemia is accentuated at relapse.

Kroeger H, Jelinek J, Estécio MR, He R, Kondo K, Chung W, Zhang L, Shen L, Kantarjian HM, Bueso-Ramos CE, Issa JP.

Blood. 2008 Aug 15;112(4):1366-73. doi: 10.1182/blood-2007-11-126227. Epub 2008 Jun 3.

PMID:
18523155
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

High-throughput methylation profiling by MCA coupled to CpG island microarray.

Estécio MR, Yan PS, Ibrahim AE, Tellez CS, Shen L, Huang TH, Issa JP.

Genome Res. 2007 Oct;17(10):1529-36. Epub 2007 Sep 4.

PMID:
17785535
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Decitabine and its role in the treatment of hematopoietic malignancies.

Plimack ER, Kantarjian HM, Issa JP.

Leuk Lymphoma. 2007 Aug;48(8):1472-81. Review.

PMID:
17701577
[PubMed - indexed for MEDLINE]
10.

Targeting the leukemia microenvironment.

Konopleva M, Andreeff M.

Curr Drug Targets. 2007 Jun;8(6):685-701. Review.

PMID:
17584025
[PubMed - indexed for MEDLINE]
11.

DNA methylation profiling of myelodysplastic syndrome hematopoietic progenitor cells during in vitro lineage-specific differentiation.

Hopfer O, Komor M, Koehler IS, Schulze M, Hoelzer D, Thiel E, Hofmann WK.

Exp Hematol. 2007 May;35(5):712-23.

PMID:
17577921
[PubMed - indexed for MEDLINE]
12.

RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis.

Boumber YA, Kondo Y, Chen X, Shen L, Gharibyan V, Konishi K, Estey E, Kantarjian H, Garcia-Manero G, Issa JP.

Cancer Res. 2007 Mar 1;67(5):1997-2005.

PMID:
17332327
[PubMed - indexed for MEDLINE]
Free Article
13.

Pharmacology of 5-Aza-2'-deoxycytidine (decitabine).

Momparler RL.

Semin Hematol. 2005 Jul;42(3 Suppl 2):S9-16. Review.

PMID:
16015507
[PubMed - indexed for MEDLINE]
14.

Detection of an alternatively spliced form of deoxycytidine kinase mRNA in the 2'-2'-difluorodeoxycytidine (gemcitabine)-resistant human ovarian cancer cell line AG6000.

Al-Madhoun AS, van der Wilt CL, Loves WJ, Padron JM, Eriksson S, Talianidis I, Peters GJ.

Biochem Pharmacol. 2004 Aug 15;68(4):601-9.

PMID:
15276067
[PubMed - indexed for MEDLINE]
15.

Progesterone receptor gene inactivation and CpG island hypermethylation in human leukemia cancer cells.

Liu ZJ, Zhang XB, Zhang Y, Yang X.

FEBS Lett. 2004 Jun 4;567(2-3):327-32.

PMID:
15178346
[PubMed - indexed for MEDLINE]
16.

Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites.

Colella S, Shen L, Baggerly KA, Issa JP, Krahe R.

Biotechniques. 2003 Jul;35(1):146-50. No abstract available.

PMID:
12866414
[PubMed - indexed for MEDLINE]
17.

Cadherin-13, a mediator of calcium-dependent cell-cell adhesion, is silenced by methylation in chronic myeloid leukemia and correlates with pretreatment risk profile and cytogenetic response to interferon alfa.

Roman-Gomez J, Castillejo JA, Jimenez A, Cervantes F, Boque C, Hermosin L, Leon A, Grañena A, Colomer D, Heiniger A, Torres A.

J Clin Oncol. 2003 Apr 15;21(8):1472-9.

PMID:
12697869
[PubMed - indexed for MEDLINE]
18.

Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines.

Veuger MJ, Honders MW, Spoelder HE, Willemze R, Barge RM.

Leuk Res. 2003 May;27(5):445-53.

PMID:
12620296
[PubMed - indexed for MEDLINE]
19.

Pretreatment deoxycytidine kinase levels predict in vivo gemcitabine sensitivity.

Kroep JR, Loves WJ, van der Wilt CL, Alvarez E, Talianidis I, Boven E, Braakhuis BJ, van Groeningen CJ, Pinedo HM, Peters GJ.

Mol Cancer Ther. 2002 Apr;1(6):371-6.

PMID:
12477049
[PubMed - indexed for MEDLINE]
Free Article
20.

Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia.

Stam RW, den Boer ML, Meijerink JP, Ebus ME, Peters GJ, Noordhuis P, Janka-Schaub GE, Armstrong SA, Korsmeyer SJ, Pieters R.

Blood. 2003 Feb 15;101(4):1270-6. Epub 2002 Oct 24.

PMID:
12406912
[PubMed - indexed for MEDLINE]
Free Article

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