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Items: 1 to 20 of 93


Perforin is a critical physiologic regulator of T-cell activation.

Lykens JE, Terrell CE, Zoller EE, Risma K, Jordan MB.

Blood. 2011 Jul 21;118(3):618-26. doi: 10.1182/blood-2010-12-324533. Epub 2011 May 23.


Gene expression profiling of peripheral blood mononuclear cells from children with active hemophagocytic lymphohistiocytosis.

Sumegi J, Barnes MG, Nestheide SV, Molleran-Lee S, Villanueva J, Zhang K, Risma KA, Grom AA, Filipovich AH.

Blood. 2011 Apr 14;117(15):e151-60. doi: 10.1182/blood-2010-08-300046. Epub 2011 Feb 16.


Platelet secretion defect in patients with familial hemophagocytic lymphohistiocytosis type 5 (FHL-5).

Sandrock K, Nakamura L, Vraetz T, Beutel K, Ehl S, Zieger B.

Blood. 2010 Dec 23;116(26):6148-50. doi: 10.1182/blood-2010-08-302943. No abstract available.


Rapid and sustained remission of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome through treatment with anakinra and corticosteroids.

Bruck N, Suttorp M, Kabus M, Heubner G, Gahr M, Pessler F.

J Clin Rheumatol. 2011 Jan;17(1):23-7. doi: 10.1097/RHU.0b013e318205092d.


Subtypes of familial hemophagocytic lymphohistiocytosis in Japan based on genetic and functional analyses of cytotoxic T lymphocytes.

Nagai K, Yamamoto K, Fujiwara H, An J, Ochi T, Suemori K, Yasumi T, Tauchi H, Koh K, Sato M, Morimoto A, Heike T, Ishii E, Yasukawa M.

PLoS One. 2010 Nov 30;5(11):e14173. doi: 10.1371/journal.pone.0014173.


Treatment of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis (EBV-HLH); update 2010.

Imashuku S.

J Pediatr Hematol Oncol. 2011 Jan;33(1):35-9. doi: 10.1097/MPH.0b013e3181f84a52.


Reduced-intensity conditioning significantly improves survival of patients with hemophagocytic lymphohistiocytosis undergoing allogeneic hematopoietic cell transplantation.

Marsh RA, Vaughn G, Kim MO, Li D, Jodele S, Joshi S, Mehta PA, Davies SM, Jordan MB, Bleesing JJ, Filipovich AH.

Blood. 2010 Dec 23;116(26):5824-31. doi: 10.1182/blood-2010-04-282392. Epub 2010 Sep 20.


Rate of decline of ferritin in patients with hemophagocytic lymphohistiocytosis as a prognostic variable for mortality.

Lin TF, Ferlic-Stark LL, Allen CE, Kozinetz CA, McClain KL.

Pediatr Blood Cancer. 2011 Jan;56(1):154-5. doi: 10.1002/pbc.22774.


X-linked lymphoproliferative syndromes: brothers or distant cousins?

Filipovich AH, Zhang K, Snow AL, Marsh RA.

Blood. 2010 Nov 4;116(18):3398-408. doi: 10.1182/blood-2010-03-275909. Epub 2010 Jul 26. Review.


Spectrum of clinical presentations in familial hemophagocytic lymphohistiocytosis type 5 patients with mutations in STXBP2.

Meeths M, Entesarian M, Al-Herz W, Chiang SC, Wood SM, Al-Ateeqi W, Almazan F, Boelens JJ, Hasle H, Ifversen M, Lund B, van den Berg JM, Gustafsson B, Hjelmqvist H, Nordenskjöld M, Bryceson YT, Henter JI.

Blood. 2010 Oct 14;116(15):2635-43. doi: 10.1182/blood-2010-05-282541. Epub 2010 Jun 17.


Critical care management of patients with hemophagocytic lymphohistiocytosis.

Buyse S, Teixeira L, Galicier L, Mariotte E, Lemiale V, Seguin A, Bertheau P, Canet E, de Labarthe A, Darmon M, Rybojad M, Schlemmer B, Azoulay E.

Intensive Care Med. 2010 Oct;36(10):1695-702. doi: 10.1007/s00134-010-1936-z. Epub 2010 Jun 8.


Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in adults characterized by high viral genome load within circulating natural killer cells.

Fox CP, Shannon-Lowe C, Gothard P, Kishore B, Neilson J, O'Connor N, Rowe M.

Clin Infect Dis. 2010 Jul 1;51(1):66-9. doi: 10.1086/653424.


Alemtuzumab as a bridge to allogeneic SCT in atypical hemophagocytic lymphohistiocytosis.

Strout MP, Seropian S, Berliner N.

Nat Rev Clin Oncol. 2010 Jul;7(7):415-20. doi: 10.1038/nrclinonc.2010.40. Epub 2010 Apr 20.


Neutralization of IFNgamma defeats haemophagocytosis in LCMV-infected perforin- and Rab27a-deficient mice.

Pachlopnik Schmid J, Ho CH, Chrétien F, Lefebvre JM, Pivert G, Kosco-Vilbois M, Ferlin W, Geissmann F, Fischer A, de Saint Basile G.

EMBO Mol Med. 2009 May;1(2):112-24. doi: 10.1002/emmm.200900009.


Hemophagocytic lymphohistiocytosis in Texas: observations on ethnicity and race.

Niece JA, Rogers ZR, Ahmad N, Langevin AM, McClain KL.

Pediatr Blood Cancer. 2010 Mar;54(3):424-8. doi: 10.1002/pbc.22359.


Comprehensive analyses and characterization of haemophagocytic lymphohistiocytosis in Vietnamese children.

My LT, Lien le B, Hsieh WC, Imamura T, Anh TN, Anh PN, Hung NT, Tseng FC, Chi CY, Dao NT, Le DT, Thinh le Q, Tung TT, Imashuku S, Thuong TC, Su IJ.

Br J Haematol. 2010 Jan;148(2):301-10. doi: 10.1111/j.1365-2141.2009.07957.x. Epub 2009 Oct 27.


Systemic JIA: new developments in the understanding of the pathophysiology and therapy.

Vastert SJ, Kuis W, Grom AA.

Best Pract Res Clin Rheumatol. 2009 Oct;23(5):655-64. doi: 10.1016/j.berh.2009.08.003. Review.


Hematopoietic stem cell transplantation for familial hemophagocytic lymphohistiocytosis and Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in Japan.

Ohga S, Kudo K, Ishii E, Honjo S, Morimoto A, Osugi Y, Sawada A, Inoue M, Tabuchi K, Suzuki N, Ishida Y, Imashuku S, Kato S, Hara T.

Pediatr Blood Cancer. 2010 Feb;54(2):299-306. doi: 10.1002/pbc.22310.


Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11.

zur Stadt U, Rohr J, Seifert W, Koch F, Grieve S, Pagel J, Strauss J, Kasper B, Nürnberg G, Becker C, Maul-Pavicic A, Beutel K, Janka G, Griffiths G, Ehl S, Hennies HC.

Am J Hum Genet. 2009 Oct;85(4):482-92. doi: 10.1016/j.ajhg.2009.09.005.


How I treat EBV lymphoproliferation.

Heslop HE.

Blood. 2009 Nov 5;114(19):4002-8. doi: 10.1182/blood-2009-07-143545. Epub 2009 Sep 1. Review.

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