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Results: 1 to 20 of 41

1.

Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling.

Sonoshita M, Aoki M, Fuwa H, Aoki K, Hosogi H, Sakai Y, Hashida H, Takabayashi A, Sasaki M, Robine S, Itoh K, Yoshioka K, Kakizaki F, Kitamura T, Oshima M, Taketo MM.

Cancer Cell. 2011 Jan 18;19(1):125-37. doi: 10.1016/j.ccr.2010.11.008.

PMID:
21251616
[PubMed - indexed for MEDLINE]
Free Article
2.

Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways.

Takebe N, Harris PJ, Warren RQ, Ivy SP.

Nat Rev Clin Oncol. 2011 Feb;8(2):97-106. doi: 10.1038/nrclinonc.2010.196. Epub 2010 Dec 14. Review.

PMID:
21151206
[PubMed - indexed for MEDLINE]
3.

Breast cancer stem cells: something out of notching?

Harrison H, Farnie G, Brennan KR, Clarke RB.

Cancer Res. 2010 Nov 15;70(22):8973-6. doi: 10.1158/0008-5472.CAN-10-1559. Epub 2010 Nov 2. Review.

PMID:
21045140
[PubMed - indexed for MEDLINE]
Free Article
4.

Notch signaling contributes to proliferation and tumor formation of human T-cell leukemia virus type 1-associated adult T-cell leukemia.

Pancewicz J, Taylor JM, Datta A, Baydoun HH, Waldmann TA, Hermine O, Nicot C.

Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16619-24. doi: 10.1073/pnas.1010722107. Epub 2010 Sep 7.

PMID:
20823234
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Determination of the gamma-secretase inhibitor MK-0752 in human plasma by online extraction and electrospray tandem mass spectrometry (HTLC-ESI-MS/MS).

Bai F, Tagen M, Colotta C, Miller L, Fouladi M, Stewart CF.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Sep 1;878(25):2348-52. doi: 10.1016/j.jchromb.2010.07.019. Epub 2010 Jul 30. Erratum in: J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Nov 1;908:161.

PMID:
20702149
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Notch as a molecular switch in neural stem cells.

Zhou ZD, Kumari U, Xiao ZC, Tan EK.

IUBMB Life. 2010 Aug;62(8):618-23. doi: 10.1002/iub.362. Review.

PMID:
20681026
[PubMed - indexed for MEDLINE]
7.

Notch signaling: emerging molecular targets for cancer therapy.

Yin L, Velazquez OC, Liu ZJ.

Biochem Pharmacol. 2010 Sep 1;80(5):690-701. doi: 10.1016/j.bcp.2010.03.026. Epub 2010 Mar 31. Review.

PMID:
20361945
[PubMed - indexed for MEDLINE]
8.

Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model.

Efferson CL, Winkelmann CT, Ware C, Sullivan T, Giampaoli S, Tammam J, Patel S, Mesiti G, Reilly JF, Gibson RE, Buser C, Yeatman T, Coppola D, Winter C, Clark EA, Draetta GF, Strack PR, Majumder PK.

Cancer Res. 2010 Mar 15;70(6):2476-84. doi: 10.1158/0008-5472.CAN-09-3114. Epub 2010 Mar 2.

PMID:
20197467
[PubMed - indexed for MEDLINE]
Free Article
9.

Targeted therapy in T-cell malignancies: dysregulation of the cellular signaling pathways.

Zhao WL.

Leukemia. 2010 Jan;24(1):13-21. doi: 10.1038/leu.2009.223. Epub 2009 Oct 29. Review.

PMID:
19865108
[PubMed - indexed for MEDLINE]
10.

Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia.

Tammam J, Ware C, Efferson C, O'Neil J, Rao S, Qu X, Gorenstein J, Angagaw M, Kim H, Kenific C, Kunii K, Leach KJ, Nikov G, Zhao J, Dai X, Hardwick J, Scott M, Winter C, Bristow L, Elbi C, Reilly JF, Look T, Draetta G, Van der Ploeg L, Kohl NE, Strack PR, Majumder PK.

Br J Pharmacol. 2009 Nov;158(5):1183-95. doi: 10.1111/j.1476-5381.2009.00389.x. Epub 2009 Sep 23.

PMID:
19775282
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Continual reassessment method vs. traditional empirically based design: modifications motivated by Phase I trials in pediatric oncology by the Pediatric Brain Tumor Consortium.

Onar A, Kocak M, Boyett JM.

J Biopharm Stat. 2009;19(3):437-55. doi: 10.1080/10543400902800486.

PMID:
19384687
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.

Rao SS, O'Neil J, Liberator CD, Hardwick JS, Dai X, Zhang T, Tyminski E, Yuan J, Kohl NE, Richon VM, Van der Ploeg LH, Carroll PM, Draetta GF, Look AT, Strack PR, Winter CG.

Cancer Res. 2009 Apr 1;69(7):3060-8. doi: 10.1158/0008-5472.CAN-08-4295. Epub 2009 Mar 24.

PMID:
19318552
[PubMed - indexed for MEDLINE]
Free Article
13.

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia.

Real PJ, Tosello V, Palomero T, Castillo M, Hernando E, de Stanchina E, Sulis ML, Barnes K, Sawai C, Homminga I, Meijerink J, Aifantis I, Basso G, Cordon-Cardo C, Ai W, Ferrando A.

Nat Med. 2009 Jan;15(1):50-8. doi: 10.1038/nm.1900. Epub 2008 Dec 21.

PMID:
19098907
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Notch, neural stem cells, and brain tumors.

Pierfelice TJ, Schreck KC, Eberhart CG, Gaiano N.

Cold Spring Harb Symp Quant Biol. 2008;73:367-75. doi: 10.1101/sqb.2008.73.013. Epub 2008 Nov 6. Review.

PMID:
19022772
[PubMed - indexed for MEDLINE]
15.

Strange bedfellows: Reelin and Notch signaling interact to regulate cell migration in the developing neocortex.

Gaiano N.

Neuron. 2008 Oct 23;60(2):189-91. doi: 10.1016/j.neuron.2008.10.009. Review.

PMID:
18957210
[PubMed - indexed for MEDLINE]
Free Article
16.

In vivo analysis of choroid plexus morphogenesis in zebrafish.

GarcĂ­a-Lecea M, Kondrychyn I, Fong SH, Ye ZR, Korzh V.

PLoS One. 2008 Sep 1;3(9):e3090. doi: 10.1371/journal.pone.0003090.

PMID:
18769618
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Development and Notch signaling requirements of the zebrafish choroid plexus.

Bill BR, Balciunas D, McCarra JA, Young ED, Xiong T, Spahn AM, Garcia-Lecea M, Korzh V, Ekker SC, Schimmenti LA.

PLoS One. 2008 Sep 3;3(9):e3114. doi: 10.1371/journal.pone.0003114.

PMID:
18769591
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

The role of Notch signaling in human cervical cancer: implications for solid tumors.

Maliekal TT, Bajaj J, Giri V, Subramanyam D, Krishna S.

Oncogene. 2008 Sep 1;27(38):5110-4. doi: 10.1038/onc.2008.224. Review.

PMID:
18758479
[PubMed - indexed for MEDLINE]
19.

Medulloblastoma stem cells.

Fan X, Eberhart CG.

J Clin Oncol. 2008 Jun 10;26(17):2821-7. doi: 10.1200/JCO.2007.15.2264. Review.

PMID:
18539960
[PubMed - indexed for MEDLINE]
Free Article
20.

Phase I and pharmacokinetic study of the oral farnesyltransferase inhibitor lonafarnib administered twice daily to pediatric patients with advanced central nervous system tumors using a modified continuous reassessment method: a Pediatric Brain Tumor Consortium Study.

Kieran MW, Packer RJ, Onar A, Blaney SM, Phillips P, Pollack IF, Geyer JR, Gururangan S, Banerjee A, Goldman S, Turner CD, Belasco JB, Broniscer A, Zhu Y, Frank E, Kirschmeier P, Statkevich P, Yver A, Boyett JM, Kun LE.

J Clin Oncol. 2007 Jul 20;25(21):3137-43.

PMID:
17634493
[PubMed - indexed for MEDLINE]
Free Article

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