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Recombinant heptameric coatomer complexes: novel tools to study isoform-specific functions.

Sahlmüller MC, Strating JR, Beck R, Eckert P, Popoff V, Haag M, Hellwig A, Berger I, Brügger B, Wieland FT.

Traffic. 2011 Jun;12(6):682-92. doi: 10.1111/j.1600-0854.2011.01177.x. Epub 2011 Mar 15.


Biochemical and morphological properties of hepatitis C virus particles and determination of their lipidome.

Merz A, Long G, Hiet MS, Brügger B, Chlanda P, Andre P, Wieland F, Krijnse-Locker J, Bartenschlager R.

J Biol Chem. 2011 Jan 28;286(4):3018-32. doi: 10.1074/jbc.M110.175018. Epub 2010 Nov 5.


The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins.

Rocks O, Gerauer M, Vartak N, Koch S, Huang ZP, Pechlivanis M, Kuhlmann J, Brunsveld L, Chandra A, Ellinger B, Waldmann H, Bastiaens PI.

Cell. 2010 Apr 30;141(3):458-71. doi: 10.1016/j.cell.2010.04.007. Epub 2010 Apr 22.


Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes.

Neumann B, Walter T, Hériché JK, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, Cetin C, Sieckmann F, Pau G, Kabbe R, Wünsche A, Satagopam V, Schmitz MH, Chapuis C, Gerlich DW, Schneider R, Eils R, Huber W, Peters JM, Hyman AA, Durbin R, Pepperkok R, Ellenberg J.

Nature. 2010 Apr 1;464(7289):721-7. doi: 10.1038/nature08869.


Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging.

Walter T, Held M, Neumann B, Hériché JK, Conrad C, Pepperkok R, Ellenberg J.

J Struct Biol. 2010 Apr;170(1):1-9. doi: 10.1016/j.jsb.2009.10.004. Epub 2009 Oct 23.


Reversible phosphorylation as a molecular switch to regulate plasma membrane targeting of acylated SH4 domain proteins.

Tournaviti S, Pietro ES, Terjung S, Schafmeier T, Wegehingel S, Ritzerfeld J, Schulz J, Smith DF, Pepperkok R, Nickel W.

Traffic. 2009 Aug;10(8):1047-60. doi: 10.1111/j.1600-0854.2009.00921.x. Epub 2009 May 12.


Analysis of DHHC acyltransferases implies overlapping substrate specificity and a two-step reaction mechanism.

Hou H, John Peter AT, Meiringer C, Subramanian K, Ungermann C.

Traffic. 2009 Aug;10(8):1061-73. doi: 10.1111/j.1600-0854.2009.00925.x. Epub 2009 May 12.


Cholesterol biosynthesis modulation regulates dengue viral replication.

Rothwell C, Lebreton A, Young Ng C, Lim JY, Liu W, Vasudevan S, Labow M, Gu F, Gaither LA.

Virology. 2009 Jun 20;389(1-2):8-19. doi: 10.1016/j.virol.2009.03.025. Epub 2009 May 5.


Differential trafficking of Src, Lyn, Yes and Fyn is specified by the state of palmitoylation in the SH4 domain.

Sato I, Obata Y, Kasahara K, Nakayama Y, Fukumoto Y, Yamasaki T, Yokoyama KK, Saito T, Yamaguchi N.

J Cell Sci. 2009 Apr 1;122(Pt 7):965-75. doi: 10.1242/jcs.034843. Epub 2009 Mar 3.


Work flow for multiplexing siRNA assays by solid-phase reverse transfection in multiwell plates.

Erfle H, Neumann B, Rogers P, Bulkescher J, Ellenberg J, Pepperkok R.

J Biomol Screen. 2008 Aug;13(7):575-80. doi: 10.1177/1087057108320133. Epub 2008 Jul 3.


Endosomal trafficking of Src tyrosine kinase.

Sandilands E, Frame MC.

Trends Cell Biol. 2008 Jul;18(7):322-9. doi: 10.1016/j.tcb.2008.05.004. Review.


Cellular phenotype recognition for high-content RNA interference genome-wide screening.

Wang J, Zhou X, Bradley PL, Chang SF, Perrimon N, Wong ST.

J Biomol Screen. 2008 Jan;13(1):29-39. doi: 10.1177/1087057107311223.


Automated classification of mitotic phenotypes of human cells using fluorescent proteins.

Harder N, Eils R, Rohr K.

Methods Cell Biol. 2008;85:539-54.


Novel cell segmentation and online SVM for cell cycle phase identification in automated microscopy.

Wang M, Zhou X, Li F, Huckins J, King RW, Wong ST.

Bioinformatics. 2008 Jan 1;24(1):94-101. Epub 2007 Nov 7.


SH4-domain-induced plasma membrane dynamization promotes bleb-associated cell motility.

Tournaviti S, Hannemann S, Terjung S, Kitzing TM, Stegmayer C, Ritzerfeld J, Walther P, Grosse R, Nickel W, Fackler OT.

J Cell Sci. 2007 Nov 1;120(Pt 21):3820-9.


Imaging in systems biology.

Megason SG, Fraser SE.

Cell. 2007 Sep 7;130(5):784-95. Review.


Rapid trafficking of c-Src, a non-palmitoylated Src-family kinase, between the plasma membrane and late endosomes/lysosomes.

Kasahara K, Nakayama Y, Kihara A, Matsuda D, Ikeda K, Kuga T, Fukumoto Y, Igarashi Y, Yamaguchi N.

Exp Cell Res. 2007 Jul 15;313(12):2651-66. Epub 2007 May 8.


Reverse transfection on cell arrays for high content screening microscopy.

Erfle H, Neumann B, Liebel U, Rogers P, Held M, Walter T, Ellenberg J, Pepperkok R.

Nat Protoc. 2007;2(2):392-9.


An RNAi screening platform to identify secretion machinery in mammalian cells.

Simpson JC, Cetin C, Erfle H, Joggerst B, Liebel U, Ellenberg J, Pepperkok R.

J Biotechnol. 2007 Apr 30;129(2):352-65. Epub 2007 Jan 14.


Single-cell quantification of molecules and rates using open-source microscope-based cytometry.

Gordon A, Colman-Lerner A, Chin TE, Benjamin KR, Yu RC, Brent R.

Nat Methods. 2007 Feb;4(2):175-81. Epub 2007 Jan 21.

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