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Results: 1 to 20 of 66

1.

Autophagy and p62 in cardiac proteinopathy.

Zheng Q, Su H, Ranek MJ, Wang X.

Circ Res. 2011 Jul 22;109(3):296-308. doi: 10.1161/CIRCRESAHA.111.244707. Epub 2011 Jun 9.

PMID:
21659648
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Atg7 induces basal autophagy and rescues autophagic deficiency in CryABR120G cardiomyocytes.

Pattison JS, Osinska H, Robbins J.

Circ Res. 2011 Jul 8;109(2):151-60. doi: 10.1161/CIRCRESAHA.110.237339. Epub 2011 May 26.

PMID:
21617129
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The ubiquitin-proteasome system in cardiomyopathies.

Schlossarek S, Carrier L.

Curr Opin Cardiol. 2011 May;26(3):190-5. doi: 10.1097/HCO.0b013e32834598fe. Review.

PMID:
21415726
[PubMed - indexed for MEDLINE]
4.

Crystal structure of R120G disease mutant of human αB-crystallin domain dimer shows closure of a groove.

Clark AR, Naylor CE, Bagnéris C, Keep NH, Slingsby C.

J Mol Biol. 2011 Apr 22;408(1):118-34. doi: 10.1016/j.jmb.2011.02.020. Epub 2011 Feb 15.

PMID:
21329698
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Cardiac myosin-binding protein C in hypertrophic cardiomyopathy: mechanisms and therapeutic opportunities.

Schlossarek S, Mearini G, Carrier L.

J Mol Cell Cardiol. 2011 Apr;50(4):613-20. doi: 10.1016/j.yjmcc.2011.01.014. Epub 2011 Feb 1. Review.

PMID:
21291890
[PubMed - indexed for MEDLINE]
6.

Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation.

Viswanathan J, Haapasalo A, Böttcher C, Miettinen R, Kurkinen KM, Lu A, Thomas A, Maynard CJ, Romano D, Hyman BT, Berezovska O, Bertram L, Soininen H, Dantuma NP, Tanzi RE, Hiltunen M.

Traffic. 2011 Mar;12(3):330-48. doi: 10.1111/j.1600-0854.2010.01149.x. Epub 2011 Jan 7.

PMID:
21143716
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Doxycycline attenuates protein aggregation in cardiomyocytes and improves survival of a mouse model of cardiac proteinopathy.

Zheng H, Tang M, Zheng Q, Kumarapeli AR, Horak KM, Tian Z, Wang X.

J Am Coll Cardiol. 2010 Oct 19;56(17):1418-26. doi: 10.1016/j.jacc.2010.01.075.

PMID:
20947000
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Manipulation of death pathways in desmin-related cardiomyopathy.

Maloyan A, Sayegh J, Osinska H, Chua BH, Robbins J.

Circ Res. 2010 May 14;106(9):1524-32. doi: 10.1161/CIRCRESAHA.109.212639. Epub 2010 Apr 1.

PMID:
20360253
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease.

Willis MS, Townley-Tilson WH, Kang EY, Homeister JW, Patterson C.

Circ Res. 2010 Feb 19;106(3):463-78. doi: 10.1161/CIRCRESAHA.109.208801. Review.

PMID:
20167943
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The ubiquitin-proteasome system in cardiac proteinopathy: a quality control perspective.

Su H, Wang X.

Cardiovasc Res. 2010 Jan 15;85(2):253-62. doi: 10.1093/cvr/cvp287. Epub 2009 Aug 20. Review.

PMID:
19696071
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Tragedy in a heartbeat: malfunctioning desmin causes skeletal and cardiac muscle disease.

Goldfarb LG, Dalakas MC.

J Clin Invest. 2009 Jul;119(7):1806-13. doi: 10.1172/JCI38027. Epub 2009 Jul 1. Review. Erratum in: J Clin Invest. 2011 Jan 4;121(1):455.

PMID:
19587455
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Biochemical and mechanical dysfunction in a mouse model of desmin-related myopathy.

Maloyan A, Osinska H, Lammerding J, Lee RT, Cingolani OH, Kass DA, Lorenz JN, Robbins J.

Circ Res. 2009 Apr 24;104(8):1021-8. doi: 10.1161/CIRCRESAHA.108.193516. Epub 2009 Mar 19.

PMID:
19299643
[PubMed - indexed for MEDLINE]
Free Article
13.

Cardioprotection requires taking out the trash.

Gottlieb RA, Finley KD, Mentzer RM Jr.

Basic Res Cardiol. 2009 Mar;104(2):169-80. doi: 10.1007/s00395-009-0011-9. Epub 2009 Feb 26. Review.

PMID:
19242643
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Intermediate filament diseases: desminopathy.

Goldfarb LG, Olivé M, Vicart P, Goebel HH.

Adv Exp Med Biol. 2008;642:131-64.

PMID:
19181099
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Build it up-Tear it down: protein quality control in the cardiac sarcomere.

Willis MS, Schisler JC, Portbury AL, Patterson C.

Cardiovasc Res. 2009 Feb 15;81(3):439-48. doi: 10.1093/cvr/cvn289. Epub 2008 Oct 29. Review.

PMID:
18974044
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Autophagy is an adaptive response in desmin-related cardiomyopathy.

Tannous P, Zhu H, Johnstone JL, Shelton JM, Rajasekaran NS, Benjamin IJ, Nguyen L, Gerard RD, Levine B, Rothermel BA, Hill JA.

Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9745-50. doi: 10.1073/pnas.0706802105. Epub 2008 Jul 9.

PMID:
18621691
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Mice expressing L345P mutant desmin exhibit morphological and functional changes of skeletal and cardiac mitochondria.

Kostareva A, Sjöberg G, Bruton J, Zhang SJ, Balogh J, Gudkova A, Hedberg B, Edström L, Westerblad H, Sejersen T.

J Muscle Res Cell Motil. 2008;29(1):25-36. doi: 10.1007/s10974-008-9139-8. Epub 2008 Jun 19.

PMID:
18563598
[PubMed - indexed for MEDLINE]
18.

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice.

Pickford F, Masliah E, Britschgi M, Lucin K, Narasimhan R, Jaeger PA, Small S, Spencer B, Rockenstein E, Levine B, Wyss-Coray T.

J Clin Invest. 2008 Jun;118(6):2190-9. doi: 10.1172/JCI33585.

PMID:
18497889
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Cardiomyocyte expression of a polyglutamine preamyloid oligomer causes heart failure.

Pattison JS, Sanbe A, Maloyan A, Osinska H, Klevitsky R, Robbins J.

Circulation. 2008 May 27;117(21):2743-51. doi: 10.1161/CIRCULATIONAHA.107.750232. Epub 2008 May 19.

PMID:
18490523
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Autophagy fights disease through cellular self-digestion.

Mizushima N, Levine B, Cuervo AM, Klionsky DJ.

Nature. 2008 Feb 28;451(7182):1069-75. doi: 10.1038/nature06639. Review.

PMID:
18305538
[PubMed - indexed for MEDLINE]
Free PMC Article

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