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Results: 1 to 20 of 42

References for PMC Articles for PubMed (Select 21725302)

1.

Niclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibition.

Gies E, Wilde I, Winget JM, Brack M, Rotblat B, Novoa CA, Balgi AD, Sorensen PH, Roberge M, Mayor T.

PLoS One. 2010 Dec 23;5(12):e14410. doi: 10.1371/journal.pone.0014410.

2.

A general chemical method to regulate protein stability in the mammalian central nervous system.

Iwamoto M, Björklund T, Lundberg C, Kirik D, Wandless TJ.

Chem Biol. 2010 Sep 24;17(9):981-8. doi: 10.1016/j.chembiol.2010.07.009.

3.

Making it easier to regulate protein stability.

Schrader EK, Wilmington SR, Matouschek A.

Chem Biol. 2010 Sep 24;17(9):917-8. doi: 10.1016/j.chembiol.2010.09.004.

4.

Targeting the undruggable proteome: the small molecules of my dreams.

Crews CM.

Chem Biol. 2010 Jun 25;17(6):551-5. doi: 10.1016/j.chembiol.2010.05.011. Review.

5.

A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes.

Dvorin JD, Martyn DC, Patel SD, Grimley JS, Collins CR, Hopp CS, Bright AT, Westenberger S, Winzeler E, Blackman MJ, Baker DA, Wandless TJ, Duraisingh MT.

Science. 2010 May 14;328(5980):910-2. doi: 10.1126/science.1188191.

6.

Rapid inactivation of proteins by rapamycin-induced rerouting to mitochondria.

Robinson MS, Sahlender DA, Foster SD.

Dev Cell. 2010 Feb 16;18(2):324-31. doi: 10.1016/j.devcel.2009.12.015.

7.

Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication.

Karlas A, Machuy N, Shin Y, Pleissner KP, Artarini A, Heuer D, Becker D, Khalil H, Ogilvie LA, Hess S, Mäurer AP, Müller E, Wolff T, Rudel T, Meyer TF.

Nature. 2010 Feb 11;463(7282):818-22. doi: 10.1038/nature08760. Epub 2010 Jan 17.

PMID:
20081832
8.

An auxin-based degron system for the rapid depletion of proteins in nonplant cells.

Nishimura K, Fukagawa T, Takisawa H, Kakimoto T, Kanemaki M.

Nat Methods. 2009 Dec;6(12):917-22. doi: 10.1038/nmeth.1401. Epub 2009 Nov 15.

PMID:
19915560
9.

Identifying druggable disease-modifying gene products.

Dixon SJ, Stockwell BR.

Curr Opin Chem Biol. 2009 Dec;13(5-6):549-55. doi: 10.1016/j.cbpa.2009.08.003. Epub 2009 Sep 7. Review.

10.

Quality control against misfolded proteins in the cytosol: a network for cell survival.

Kubota H.

J Biochem. 2009 Nov;146(5):609-16. doi: 10.1093/jb/mvp139. Epub 2009 Sep 7. Review.

PMID:
19737776
11.

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

Luo J, Emanuele MJ, Li D, Creighton CJ, Schlabach MR, Westbrook TF, Wong KK, Elledge SJ.

Cell. 2009 May 29;137(5):835-48. doi: 10.1016/j.cell.2009.05.006.

12.

Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels.

Pruett-Miller SM, Reading DW, Porter SN, Porteus MH.

PLoS Genet. 2009 Feb;5(2):e1000376. doi: 10.1371/journal.pgen.1000376. Epub 2009 Feb 13.

13.

Knocking down barriers: advances in siRNA delivery.

Whitehead KA, Langer R, Anderson DG.

Nat Rev Drug Discov. 2009 Feb;8(2):129-38. doi: 10.1038/nrd2742. Review. Erratum in: Nat Rev Drug Discov. 2009 Jun;8(6):516.

PMID:
19180106
14.

Chemical control of protein stability and function in living mice.

Banaszynski LA, Sellmyer MA, Contag CH, Wandless TJ, Thorne SH.

Nat Med. 2008 Oct;14(10):1123-7. doi: 10.1038/nm.1754. Epub 2008 Sep 28.

15.

RNA interference screen for human genes associated with West Nile virus infection.

Krishnan MN, Ng A, Sukumaran B, Gilfoy FD, Uchil PD, Sultana H, Brass AL, Adametz R, Tsui M, Qian F, Montgomery RR, Lev S, Mason PW, Koski RA, Elledge SJ, Xavier RJ, Agaisse H, Fikrig E.

Nature. 2008 Sep 11;455(7210):242-5. doi: 10.1038/nature07207.

16.

HaloTag: a novel protein labeling technology for cell imaging and protein analysis.

Los GV, Encell LP, McDougall MG, Hartzell DD, Karassina N, Zimprich C, Wood MG, Learish R, Ohana RF, Urh M, Simpson D, Mendez J, Zimmerman K, Otto P, Vidugiris G, Zhu J, Darzins A, Klaubert DH, Bulleit RF, Wood KV.

ACS Chem Biol. 2008 Jun 20;3(6):373-82. doi: 10.1021/cb800025k.

PMID:
18533659
17.

Design and testing of zinc finger nucleases for use in mammalian cells.

Porteus M.

Methods Mol Biol. 2008;435:47-61. doi: 10.1007/978-1-59745-232-8_4.

PMID:
18370067
18.

Genetic knockouts and knockins in human somatic cells.

Rago C, Vogelstein B, Bunz F.

Nat Protoc. 2007;2(11):2734-46.

PMID:
18007609
19.

Rapid control of protein level in the apicomplexan Toxoplasma gondii.

Herm-Götz A, Agop-Nersesian C, Münter S, Grimley JS, Wandless TJ, Frischknecht F, Meissner M.

Nat Methods. 2007 Dec;4(12):1003-5. Epub 2007 Nov 11. Erratum in: Nat Methods. 2008 Jan;5(1):113.

20.

How many drug targets are there?

Overington JP, Al-Lazikani B, Hopkins AL.

Nat Rev Drug Discov. 2006 Dec;5(12):993-6. Review.

PMID:
17139284
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