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Items: 1 to 20 of 25


Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.

Wang H, Morita M, Yang X, Suzuki T, Yang W, Wang J, Ito K, Wang Q, Zhao C, Bartlam M, Yamamoto T, Rao Z.

EMBO J. 2010 Aug 4;29(15):2566-76. doi: 10.1038/emboj.2010.152. Epub 2010 Jul 13.


Structural basis for the antiproliferative activity of the Tob-hCaf1 complex.

Horiuchi M, Takeuchi K, Noda N, Muroya N, Suzuki T, Nakamura T, Kawamura-Tsuzuku J, Takahasi K, Yamamoto T, Inagaki F.

J Biol Chem. 2009 May 8;284(19):13244-55. doi: 10.1074/jbc.M809250200. Epub 2009 Mar 10.


A different conformation for EGC stator subcomplex in solution and in the assembled yeast V-ATPase: possible implications for regulatory disassembly.

Diepholz M, Venzke D, Prinz S, Batisse C, Flörchinger B, Rössle M, Svergun DI, Böttcher B, Féthière J.

Structure. 2008 Dec 10;16(12):1789-98. doi: 10.1016/j.str.2008.09.010.


GraFix: sample preparation for single-particle electron cryomicroscopy.

Kastner B, Fischer N, Golas MM, Sander B, Dube P, Boehringer D, Hartmuth K, Deckert J, Hauer F, Wolf E, Uchtenhagen H, Urlaub H, Herzog F, Peters JM, Poerschke D, Lührmann R, Stark H.

Nat Methods. 2008 Jan;5(1):53-5. Epub 2007 Dec 23.


The 1.4-A crystal structure of the S. pombe Pop2p deadenylase subunit unveils the configuration of an active enzyme.

Jonstrup AT, Andersen KR, Van LB, Brodersen DE.

Nucleic Acids Res. 2007;35(9):3153-64. Epub 2007 Apr 22.


Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization.

Scheres SH, Gao H, Valle M, Herman GT, Eggermont PP, Frank J, Carazo JM.

Nat Methods. 2007 Jan;4(1):27-9. Epub 2006 Dec 10.


UCSF Chimera--a visualization system for exploratory research and analysis.

Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC, Ferrin TE.

J Comput Chem. 2004 Oct;25(13):1605-12.


X-ray structure and activity of the yeast Pop2 protein: a nuclease subunit of the mRNA deadenylase complex.

Thore S, Mauxion F, Séraphin B, Suck D.

EMBO Rep. 2003 Dec;4(12):1150-5. Epub 2003 Nov 14.


Global control of gene expression in yeast by the Ccr4-Not complex.

Collart MA.

Gene. 2003 Aug 14;313:1-16. Review.


Functional organization of the yeast proteome by systematic analysis of protein complexes.

Gavin AC, Bösche M, Krause R, Grandi P, Marzioch M, Bauer A, Schultz J, Rick JM, Michon AM, Cruciat CM, Remor M, Höfert C, Schelder M, Brajenovic M, Ruffner H, Merino A, Klein K, Hudak M, Dickson D, Rudi T, Gnau V, Bauch A, Bastuck S, Huhse B, Leutwein C, Heurtier MA, Copley RR, Edelmann A, Querfurth E, Rybin V, Drewes G, Raida M, Bouwmeester T, Bork P, Seraphin B, Kuster B, Neubauer G, Superti-Furga G.

Nature. 2002 Jan 10;415(6868):141-7.


Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex.

Chen J, Rappsilber J, Chiang YC, Russell P, Mann M, Denis CL.

J Mol Biol. 2001 Dec 7;314(4):683-94.


The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation.

Daugeron MC, Mauxion F, Séraphin B.

Nucleic Acids Res. 2001 Jun 15;29(12):2448-55.


The tandem affinity purification (TAP) method: a general procedure of protein complex purification.

Puig O, Caspary F, Rigaut G, Rutz B, Bouveret E, Bragado-Nilsson E, Wilm M, Séraphin B.

Methods. 2001 Jul;24(3):218-29. Review.


The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae.

Tucker M, Valencia-Sanchez MA, Staples RR, Chen J, Denis CL, Parker R.

Cell. 2001 Feb 9;104(3):377-86.


Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme.

Liu HY, Chiang YC, Pan J, Chen J, Salvadore C, Audino DC, Badarinarayana V, Palaniswamy V, Anderson B, Denis CL.

J Biol Chem. 2001 Mar 9;276(10):7541-8. Epub 2000 Dec 11.


The essential function of Not1 lies within the Ccr4-Not complex.

Maillet L, Tu C, Hong YK, Shuster EO, Collart MA.

J Mol Biol. 2000 Oct 20;303(2):131-43.


Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits.

Albert TK, Lemaire M, van Berkum NL, Gentz R, Collart MA, Timmers HT.

Nucleic Acids Res. 2000 Feb 1;28(3):809-17.


The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.

Bai Y, Salvadore C, Chiang YC, Collart MA, Liu HY, Denis CL.

Mol Cell Biol. 1999 Oct;19(10):6642-51.


The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively.

Liu HY, Badarinarayana V, Audino DC, Rappsilber J, Mann M, Denis CL.

EMBO J. 1998 Feb 16;17(4):1096-106.

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