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Results: 1 to 20 of 50

1.

An algorithmic framework for predicting side effects of drugs.

Atias N, Sharan R.

J Comput Biol. 2011 Mar;18(3):207-18. doi: 10.1089/cmb.2010.0255.

PMID:
21385029
[PubMed - indexed for MEDLINE]
2.

Combining drug and gene similarity measures for drug-target elucidation.

Perlman L, Gottlieb A, Atias N, Ruppin E, Sharan R.

J Comput Biol. 2011 Feb;18(2):133-45. doi: 10.1089/cmb.2010.0213.

PMID:
21314453
[PubMed - indexed for MEDLINE]
3.

Computational approaches for drug repositioning and combination therapy design.

Kotelnikova E, Yuryev A, Mazo I, Daraselia N.

J Bioinform Comput Biol. 2010 Jun;8(3):593-606.

PMID:
20556864
[PubMed - indexed for MEDLINE]
4.

The human phenotype ontology.

Robinson PN, Mundlos S.

Clin Genet. 2010 Jun;77(6):525-34. doi: 10.1111/j.1399-0004.2010.01436.x. Epub 2010 Feb 11. Review.

PMID:
20412080
[PubMed - indexed for MEDLINE]
5.

A side effect resource to capture phenotypic effects of drugs.

Kuhn M, Campillos M, Letunic I, Jensen LJ, Bork P.

Mol Syst Biol. 2010;6:343. doi: 10.1038/msb.2009.98. Epub 2010 Jan 19.

PMID:
20087340
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

DCDB: drug combination database.

Liu Y, Hu B, Fu C, Chen X.

Bioinformatics. 2010 Feb 15;26(4):587-8. doi: 10.1093/bioinformatics/btp697. Epub 2009 Dec 23.

PMID:
20031966
[PubMed - indexed for MEDLINE]
Free Article
7.

Human disease-drug network based on genomic expression profiles.

Hu G, Agarwal P.

PLoS One. 2009 Aug 6;4(8):e6536. doi: 10.1371/journal.pone.0006536.

PMID:
19657382
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Building disease-specific drug-protein connectivity maps from molecular interaction networks and PubMed abstracts.

Li J, Zhu X, Chen JY.

PLoS Comput Biol. 2009 Jul;5(7):e1000450. doi: 10.1371/journal.pcbi.1000450. Epub 2009 Jul 31.

PMID:
19649302
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Supervised prediction of drug-target interactions using bipartite local models.

Bleakley K, Yamanishi Y.

Bioinformatics. 2009 Sep 15;25(18):2397-403. doi: 10.1093/bioinformatics/btp433. Epub 2009 Jul 15.

PMID:
19605421
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Drug discovery using chemical systems biology: repositioning the safe medicine Comtan to treat multi-drug and extensively drug resistant tuberculosis.

Kinnings SL, Liu N, Buchmeier N, Tonge PJ, Xie L, Bourne PE.

PLoS Comput Biol. 2009 Jul;5(7):e1000423. doi: 10.1371/journal.pcbi.1000423. Epub 2009 Jul 3.

PMID:
19578428
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Systematic evaluation of drug-disease relationships to identify leads for novel drug uses.

Chiang AP, Butte AJ.

Clin Pharmacol Ther. 2009 Nov;86(5):507-10. doi: 10.1038/clpt.2009.103. Epub 2009 Jul 1.

PMID:
19571805
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Infrastructure for the life sciences: design and implementation of the UniProt website.

Jain E, Bairoch A, Duvaud S, Phan I, Redaschi N, Suzek BE, Martin MJ, McGarvey P, Gasteiger E.

BMC Bioinformatics. 2009 May 8;10:136. doi: 10.1186/1471-2105-10-136.

PMID:
19426475
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Generating genome-scale candidate gene lists for pharmacogenomics.

Hansen NT, Brunak S, Altman RB.

Clin Pharmacol Ther. 2009 Aug;86(2):183-9. doi: 10.1038/clpt.2009.42. Epub 2009 Apr 15.

PMID:
19369935
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes.

Lage K, Hansen NT, Karlberg EO, Eklund AC, Roque FS, Donahoe PK, Szallasi Z, Jensen TS, Brunak S.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20870-5. doi: 10.1073/pnas.0810772105. Epub 2008 Dec 22.

PMID:
19104045
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Fast gene ontology based clustering for microarray experiments.

Ovaska K, Laakso M, Hautaniemi S.

BioData Min. 2008 Nov 21;1(1):11. doi: 10.1186/1756-0381-1-11.

PMID:
19025591
[PubMed]
Free PMC Article
16.

ArrayExpress update--from an archive of functional genomics experiments to the atlas of gene expression.

Parkinson H, Kapushesky M, Kolesnikov N, Rustici G, Shojatalab M, Abeygunawardena N, Berube H, Dylag M, Emam I, Farne A, Holloway E, Lukk M, Malone J, Mani R, Pilicheva E, Rayner TF, Rezwan F, Sharma A, Williams E, Bradley XZ, Adamusiak T, Brandizi M, Burdett T, Coulson R, Krestyaninova M, Kurnosov P, Maguire E, Neogi SG, Rocca-Serra P, Sansone SA, Sklyar N, Zhao M, Sarkans U, Brazma A.

Nucleic Acids Res. 2009 Jan;37(Database issue):D868-72. doi: 10.1093/nar/gkn889. Epub 2008 Nov 10.

PMID:
19015125
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The Human Phenotype Ontology: a tool for annotating and analyzing human hereditary disease.

Robinson PN, Köhler S, Bauer S, Seelow D, Horn D, Mundlos S.

Am J Hum Genet. 2008 Nov;83(5):610-5. doi: 10.1016/j.ajhg.2008.09.017. Epub 2008 Oct 23.

PMID:
18950739
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

DrugBank: a knowledgebase for drugs, drug actions and drug targets.

Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M.

Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. Epub 2007 Nov 29.

PMID:
18048412
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The BioGRID Interaction Database: 2008 update.

Breitkreutz BJ, Stark C, Reguly T, Boucher L, Breitkreutz A, Livstone M, Oughtred R, Lackner DH, Bähler J, Wood V, Dolinski K, Tyers M.

Nucleic Acids Res. 2008 Jan;36(Database issue):D637-40. Epub 2007 Nov 13.

PMID:
18000002
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

SuperTarget and Matador: resources for exploring drug-target relationships.

Günther S, Kuhn M, Dunkel M, Campillos M, Senger C, Petsalaki E, Ahmed J, Urdiales EG, Gewiess A, Jensen LJ, Schneider R, Skoblo R, Russell RB, Bourne PE, Bork P, Preissner R.

Nucleic Acids Res. 2008 Jan;36(Database issue):D919-22. Epub 2007 Oct 16.

PMID:
17942422
[PubMed - indexed for MEDLINE]
Free PMC Article

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