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Items: 1 to 20 of 33

1.

Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells.

Loewer A, Batchelor E, Gaglia G, Lahav G.

Cell. 2010 Jul 9;142(1):89-100. doi: 10.1016/j.cell.2010.05.031.

2.

Single-cell NF-kappaB dynamics reveal digital activation and analogue information processing.

Tay S, Hughey JJ, Lee TK, Lipniacki T, Quake SR, Covert MW.

Nature. 2010 Jul 8;466(7303):267-71. doi: 10.1038/nature09145. Epub 2010 Jun 27.

3.

DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases.

Yajima H, Lee KJ, Zhang S, Kobayashi J, Chen BP.

J Mol Biol. 2009 Jan 23;385(3):800-10. doi: 10.1016/j.jmb.2008.11.036. Epub 2008 Nov 27.

4.

A PI3-kinase-mediated negative feedback regulates neuronal excitability.

Howlett E, Lin CC, Lavery W, Stern M.

PLoS Genet. 2008 Nov;4(11):e1000277. doi: 10.1371/journal.pgen.1000277. Epub 2008 Nov 28.

5.

ATR: an essential regulator of genome integrity.

Cimprich KA, Cortez D.

Nat Rev Mol Cell Biol. 2008 Aug;9(8):616-27. doi: 10.1038/nrm2450. Epub 2008 Jul 2. Review.

6.

Regulation of cell signaling dynamics by the protein kinase-scaffold Ste5.

Hao N, Nayak S, Behar M, Shanks RH, Nagiec MJ, Errede B, Hasty J, Elston TC, Dohlman HG.

Mol Cell. 2008 Jun 6;30(5):649-56. doi: 10.1016/j.molcel.2008.04.016.

7.

Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage.

Batchelor E, Mock CS, Bhan I, Loewer A, Lahav G.

Mol Cell. 2008 May 9;30(3):277-89. doi: 10.1016/j.molcel.2008.03.016.

8.

Coping with stress: multiple ways to activate p53.

Horn HF, Vousden KH.

Oncogene. 2007 Feb 26;26(9):1306-16. Review.

PMID:
17322916
9.

Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate.

Santos SD, Verveer PJ, Bastiaens PI.

Nat Cell Biol. 2007 Mar;9(3):324-30. Epub 2007 Feb 18.

PMID:
17310240
10.

Wip1 phosphatase modulates ATM-dependent signaling pathways.

Shreeram S, Demidov ON, Hee WK, Yamaguchi H, Onishi N, Kek C, Timofeev ON, Dudgeon C, Fornace AJ, Anderson CW, Minami Y, Appella E, Bulavin DV.

Mol Cell. 2006 Sep 1;23(5):757-64.

11.

Oscillations and variability in the p53 system.

Geva-Zatorsky N, Rosenfeld N, Itzkovitz S, Milo R, Sigal A, Dekel E, Yarnitzky T, Liron Y, Polak P, Lahav G, Alon U.

Mol Syst Biol. 2006;2:2006.0033. Epub 2006 Jun 13.

12.

An excitable gene regulatory circuit induces transient cellular differentiation.

Süel GM, Garcia-Ojalvo J, Liberman LM, Elowitz MB.

Nature. 2006 Mar 23;440(7083):545-50.

PMID:
16554821
13.

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks.

Jazayeri A, Falck J, Lukas C, Bartek J, Smith GC, Lukas J, Jackson SP.

Nat Cell Biol. 2006 Jan;8(1):37-45. Epub 2005 Dec 4.

PMID:
16327781
14.

PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints.

Lu X, Nannenga B, Donehower LA.

Genes Dev. 2005 May 15;19(10):1162-74. Epub 2005 May 3.

15.

The p53 pathway: positive and negative feedback loops.

Harris SL, Levine AJ.

Oncogene. 2005 Apr 18;24(17):2899-908. Review.

PMID:
15838523
16.

Post-translational modification of p53 in tumorigenesis.

Bode AM, Dong Z.

Nat Rev Cancer. 2004 Oct;4(10):793-805. Review.

PMID:
15510160
17.

Accelerated MDM2 auto-degradation induced by DNA-damage kinases is required for p53 activation.

Stommel JM, Wahl GM.

EMBO J. 2004 Apr 7;23(7):1547-56. Epub 2004 Mar 18.

18.

Dynamics of the p53-Mdm2 feedback loop in individual cells.

Lahav G, Rosenfeld N, Sigal A, Geva-Zatorsky N, Levine AJ, Elowitz MB, Alon U.

Nat Genet. 2004 Feb;36(2):147-50. Epub 2004 Jan 18.

19.

Functional role of Mdm2 phosphorylation by ATR in attenuation of p53 nuclear export.

Shinozaki T, Nota A, Taya Y, Okamoto K.

Oncogene. 2003 Dec 4;22(55):8870-80.

PMID:
14654783
20.

A quantitative description of membrane current and its application to conduction and excitation in nerve.

HODGKIN AL, HUXLEY AF.

J Physiol. 1952 Aug;117(4):500-44. No abstract available.

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