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Items: 1 to 20 of 70


MDC1 collaborates with TopBP1 in DNA replication checkpoint control.

Wang J, Gong Z, Chen J.

J Cell Biol. 2011 Apr 18;193(2):267-73. doi: 10.1083/jcb.201010026. Epub 2011 Apr 11.


Detection of nascent RNA, single-copy DNA and protein localization by immunoFISH in mouse germ cells and preimplantation embryos.

Namekawa SH, Lee JT.

Nat Protoc. 2011 Mar;6(3):270-84. doi: 10.1038/nprot.2010.195. Epub 2011 Feb 10.


Nuclear organization and dosage compensation.

Chow JC, Heard E.

Cold Spring Harb Perspect Biol. 2010 Nov;2(11):a000604. doi: 10.1101/cshperspect.a000604. Epub 2010 Oct 13. Review.


The X as model for RNA's niche in epigenomic regulation.

Lee JT.

Cold Spring Harb Perspect Biol. 2010 Sep;2(9):a003749. doi: 10.1101/cshperspect.a003749. Epub 2010 Mar 31. Review.


ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks.

Shanbhag NM, Rafalska-Metcalf IU, Balane-Bolivar C, Janicki SM, Greenberg RA.

Cell. 2010 Jun 11;141(6):970-81. doi: 10.1016/j.cell.2010.04.038.


Two-step imprinted X inactivation: repeat versus genic silencing in the mouse.

Namekawa SH, Payer B, Huynh KD, Jaenisch R, Lee JT.

Mol Cell Biol. 2010 Jul;30(13):3187-205. doi: 10.1128/MCB.00227-10. Epub 2010 Apr 19.


Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8.

Santos MA, Huen MS, Jankovic M, Chen HT, López-Contreras AJ, Klein IA, Wong N, Barbancho JL, Fernandez-Capetillo O, Nussenzweig MC, Chen J, Nussenzweig A.

J Exp Med. 2010 May 10;207(5):973-81. doi: 10.1084/jem.20092308. Epub 2010 Apr 12.


DNA double strand break repair, chromosome synapsis and transcriptional silencing in meiosis.

Inagaki A, Schoenmakers S, Baarends WM.

Epigenetics. 2010 May 16;5(4):255-66. Epub 2010 May 16. Review.


RNF8-dependent histone modifications regulate nucleosome removal during spermatogenesis.

Lu LY, Wu J, Ye L, Gavrilina GB, Saunders TL, Yu X.

Dev Cell. 2010 Mar 16;18(3):371-84. doi: 10.1016/j.devcel.2010.01.010. Epub 2010 Feb 11.


BRCA1 and its toolbox for the maintenance of genome integrity.

Huen MS, Sy SM, Chen J.

Nat Rev Mol Cell Biol. 2010 Feb;11(2):138-48. doi: 10.1038/nrm2831. Epub 2009 Dec 23. Review.


Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks.

Galanty Y, Belotserkovskaya R, Coates J, Polo S, Miller KM, Jackson SP.

Nature. 2009 Dec 17;462(7275):935-9. doi: 10.1038/nature08657.


Sex chromosome inactivation in the male.

Yan W, McCarrey JR.

Epigenetics. 2009 Oct 1;4(7):452-6. Epub 2009 Oct 25.


Fanconi anemia: a paradigm of discovering molecular pathways from patients.

Andreassen PR, Niedernhofer LJ.

Mutat Res. 2009 Jul 31;668(1-2):1-3. doi: 10.1016/j.mrfmmm.2009.06.007. Epub 2009 Jun 21. No abstract available.


XY and ZW: is meiotic sex chromosome inactivation the rule in evolution?

Namekawa SH, Lee JT.

PLoS Genet. 2009 May;5(5):e1000493. doi: 10.1371/journal.pgen.1000493. Epub 2009 May 22. Review. No abstract available.


Many X-linked microRNAs escape meiotic sex chromosome inactivation.

Song R, Ro S, Michaels JD, Park C, McCarrey JR, Yan W.

Nat Genet. 2009 Apr;41(4):488-93. doi: 10.1038/ng.338. Epub 2009 Mar 22.


ATR/Mec1: coordinating fork stability and repair.

Friedel AM, Pike BL, Gasser SM.

Curr Opin Cell Biol. 2009 Apr;21(2):237-44. doi: 10.1016/ Epub 2009 Feb 21. Review.


The consequences of asynapsis for mammalian meiosis.

Burgoyne PS, Mahadevaiah SK, Turner JM.

Nat Rev Genet. 2009 Mar;10(3):207-16. doi: 10.1038/nrg2505. Review.


Sumoylation precedes accumulation of phosphorylated H2AX on sex chromosomes during their meiotic inactivation.

Vigodner M.

Chromosome Res. 2009;17(1):37-45. doi: 10.1007/s10577-008-9006-x. Epub 2009 Jan 21.


Extensive meiotic asynapsis in mice antagonises meiotic silencing of unsynapsed chromatin and consequently disrupts meiotic sex chromosome inactivation.

Mahadevaiah SK, Bourc'his D, de Rooij DG, Bestor TH, Turner JM, Burgoyne PS.

J Cell Biol. 2008 Jul 28;182(2):263-76. doi: 10.1083/jcb.200710195.


ATR: an essential regulator of genome integrity.

Cimprich KA, Cortez D.

Nat Rev Mol Cell Biol. 2008 Aug;9(8):616-27. doi: 10.1038/nrm2450. Epub 2008 Jul 2. Review.

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