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Results: 1 to 20 of 67

1.

Mammalian microRNAs predominantly act to decrease target mRNA levels.

Guo H, Ingolia NT, Weissman JS, Bartel DP.

Nature. 2010 Aug 12;466(7308):835-40. doi: 10.1038/nature09267.

PMID:
20703300
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Argonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liver.

Grimm D, Wang L, Lee JS, Schürmann N, Gu S, Börner K, Storm TA, Kay MA.

J Clin Invest. 2010 Sep;120(9):3106-19. doi: 10.1172/JCI43565. Epub 2010 Aug 9.

PMID:
20697157
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The human cytomegalovirus microRNA miR-UL112 acts synergistically with a cellular microRNA to escape immune elimination.

Nachmani D, Lankry D, Wolf DG, Mandelboim O.

Nat Immunol. 2010 Sep;11(9):806-13. doi: 10.1038/ni.1916. Epub 2010 Aug 8.

PMID:
20694010
[PubMed - indexed for MEDLINE]
4.

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma.

Medina PP, Nolde M, Slack FJ.

Nature. 2010 Sep 2;467(7311):86-90. doi: 10.1038/nature09284. Epub 2010 Aug 8.

PMID:
20693987
[PubMed - indexed for MEDLINE]
5.

MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis.

Anand S, Majeti BK, Acevedo LM, Murphy EA, Mukthavaram R, Scheppke L, Huang M, Shields DJ, Lindquist JN, Lapinski PE, King PD, Weis SM, Cheresh DA.

Nat Med. 2010 Aug;16(8):909-14. doi: 10.1038/nm.2186. Epub 2010 Aug 1.

PMID:
20676106
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Cellular microRNAs 200b and 429 regulate the Epstein-Barr virus switch between latency and lytic replication.

Ellis-Connell AL, Iempridee T, Xu I, Mertz JE.

J Virol. 2010 Oct;84(19):10329-43. doi: 10.1128/JVI.00923-10. Epub 2010 Jul 28.

PMID:
20668090
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A collection of target mimics for comprehensive analysis of microRNA function in Arabidopsis thaliana.

Todesco M, Rubio-Somoza I, Paz-Ares J, Weigel D.

PLoS Genet. 2010 Jul 22;6(7):e1001031. doi: 10.1371/journal.pgen.1001031.

PMID:
20661442
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Target RNA-directed trimming and tailing of small silencing RNAs.

Ameres SL, Horwich MD, Hung JH, Xu J, Ghildiyal M, Weng Z, Zamore PD.

Science. 2010 Jun 18;328(5985):1534-9. doi: 10.1126/science.1187058.

PMID:
20558712
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A direct comparison of anti-microRNA oligonucleotide potency.

Lennox KA, Behlke MA.

Pharm Res. 2010 Sep;27(9):1788-99. doi: 10.1007/s11095-010-0156-0. Epub 2010 Apr 28.

PMID:
20424893
[PubMed - indexed for MEDLINE]
10.

Mammalian microRNAs: experimental evaluation of novel and previously annotated genes.

Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP.

Genes Dev. 2010 May 15;24(10):992-1009. doi: 10.1101/gad.1884710. Epub 2010 Apr 22.

PMID:
20413612
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Inhibiting miRNA in Caenorhabditis elegans using a potent and selective antisense reagent.

Zheng G, Ambros V, Li WH.

Silence. 2010 Apr 1;1(1):9. doi: 10.1186/1758-907X-1-9.

PMID:
20359322
[PubMed]
Free PMC Article
12.

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles.

Davis ME, Zuckerman JE, Choi CH, Seligson D, Tolcher A, Alabi CA, Yen Y, Heidel JD, Ribas A.

Nature. 2010 Apr 15;464(7291):1067-70. doi: 10.1038/nature08956. Epub 2010 Mar 21.

PMID:
20305636
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Five questions about viruses and microRNAs.

Cullen BR.

PLoS Pathog. 2010 Feb 26;6(2):e1000787. doi: 10.1371/journal.ppat.1000787. Review. No abstract available.

PMID:
20195463
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Double-detargeted oncolytic adenovirus shows replication arrest in liver cells and retains neuroendocrine cell killing ability.

Leja J, Nilsson B, Yu D, Gustafson E, Akerström G, Oberg K, Giandomenico V, Essand M.

PLoS One. 2010 Jan 27;5(1):e8916. doi: 10.1371/journal.pone.0008916.

PMID:
20111709
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Rational design of cationic lipids for siRNA delivery.

Semple SC, Akinc A, Chen J, Sandhu AP, Mui BL, Cho CK, Sah DW, Stebbing D, Crosley EJ, Yaworski E, Hafez IM, Dorkin JR, Qin J, Lam K, Rajeev KG, Wong KF, Jeffs LB, Nechev L, Eisenhardt ML, Jayaraman M, Kazem M, Maier MA, Srinivasulu M, Weinstein MJ, Chen Q, Alvarez R, Barros SA, De S, Klimuk SK, Borland T, Kosovrasti V, Cantley WL, Tam YK, Manoharan M, Ciufolini MA, Tracy MA, de Fougerolles A, MacLachlan I, Cullis PR, Madden TD, Hope MJ.

Nat Biotechnol. 2010 Feb;28(2):172-6. doi: 10.1038/nbt.1602. Epub 2010 Jan 17.

PMID:
20081866
[PubMed - indexed for MEDLINE]
16.

Lipid-like materials for low-dose, in vivo gene silencing.

Love KT, Mahon KP, Levins CG, Whitehead KA, Querbes W, Dorkin JR, Qin J, Cantley W, Qin LL, Racie T, Frank-Kamenetsky M, Yip KN, Alvarez R, Sah DW, de Fougerolles A, Fitzgerald K, Koteliansky V, Akinc A, Langer R, Anderson DG.

Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):1864-9. doi: 10.1073/pnas.0910603106. Epub 2010 Jan 11. Erratum in: Proc Natl Acad Sci U S A. 2010 May 25;107(21):9915.

PMID:
20080679
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Regulation of KSHV lytic switch protein expression by a virus-encoded microRNA: an evolutionary adaptation that fine-tunes lytic reactivation.

Bellare P, Ganem D.

Cell Host Microbe. 2009 Dec 17;6(6):570-5. doi: 10.1016/j.chom.2009.11.008.

PMID:
20006845
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Regression of murine lung tumors by the let-7 microRNA.

Trang P, Medina PP, Wiggins JF, Ruffino L, Kelnar K, Omotola M, Homer R, Brown D, Bader AG, Weidhaas JB, Slack FJ.

Oncogene. 2010 Mar 18;29(11):1580-7. doi: 10.1038/onc.2009.445. Epub 2009 Dec 7.

PMID:
19966857
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection.

Lanford RE, Hildebrandt-Eriksen ES, Petri A, Persson R, Lindow M, Munk ME, Kauppinen S, Ørum H.

Science. 2010 Jan 8;327(5962):198-201. doi: 10.1126/science.1178178. Epub 2009 Dec 3.

PMID:
19965718
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms.

Loya CM, Lu CS, Van Vactor D, Fulga TA.

Nat Methods. 2009 Dec;6(12):897-903. doi: 10.1038/nmeth.1402. Epub 2009 Nov 15.

PMID:
19915559
[PubMed - indexed for MEDLINE]
Free PMC Article

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