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Results: 1 to 20 of 64

References for PMC Articles for PubMed (Select 21520201)

1.

Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice.

Nath B, Levin I, Csak T, Petrasek J, Mueller C, Kodys K, Catalano D, Mandrekar P, Szabo G.

Hepatology. 2011 May;53(5):1526-37. doi: 10.1002/hep.24256.

2.

Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ.

Chacko BK, Reily C, Srivastava A, Johnson MS, Ye Y, Ulasova E, Agarwal A, Zinn KR, Murphy MP, Kalyanaraman B, Darley-Usmar V.

Biochem J. 2010 Nov 15;432(1):9-19. doi: 10.1042/BJ20100308.

3.

Chronic ethanol consumption enhances sensitivity to Ca(2+)-mediated opening of the mitochondrial permeability transition pore and increases cyclophilin D in liver.

King AL, Swain TM, Dickinson DA, Lesort MJ, Bailey SM.

Am J Physiol Gastrointest Liver Physiol. 2010 Oct;299(4):G954-66. doi: 10.1152/ajpgi.00246.2010. Epub 2010 Jul 22.

4.

Animal and human studies with the mitochondria-targeted antioxidant MitoQ.

Smith RA, Murphy MP.

Ann N Y Acad Sci. 2010 Jul;1201:96-103. doi: 10.1111/j.1749-6632.2010.05627.x. Review.

PMID:
20649545
5.

A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease.

Snow BJ, Rolfe FL, Lockhart MM, Frampton CM, O'Sullivan JD, Fung V, Smith RA, Murphy MP, Taylor KM; Protect Study Group.

Mov Disord. 2010 Aug 15;25(11):1670-4. doi: 10.1002/mds.23148.

PMID:
20568096
6.

The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients.

Gane EJ, Weilert F, Orr DW, Keogh GF, Gibson M, Lockhart MM, Frampton CM, Taylor KM, Smith RA, Murphy MP.

Liver Int. 2010 Aug;30(7):1019-26. doi: 10.1111/j.1478-3231.2010.02250.x. Epub 2010 May 18.

PMID:
20492507
7.

MitoQ administration prevents endotoxin-induced cardiac dysfunction.

Supinski GS, Murphy MP, Callahan LA.

Am J Physiol Regul Integr Comp Physiol. 2009 Oct;297(4):R1095-102. doi: 10.1152/ajpregu.90902.2008. Epub 2009 Aug 5.

8.

Current experimental perspectives on the clinical progression of alcoholic liver disease.

Breitkopf K, Nagy LE, Beier JI, Mueller S, Weng H, Dooley S.

Alcohol Clin Exp Res. 2009 Oct;33(10):1647-55. doi: 10.1111/j.1530-0277.2009.01015.x. Epub 2009 Jul 23. Review.

PMID:
19645734
9.

Ethanol and liver: recent advances in the mechanisms of ethanol-induced hepatosteatosis.

Zeng T, Xie KQ.

Arch Toxicol. 2009 Dec;83(12):1075-81. doi: 10.1007/s00204-009-0457-4.

PMID:
19588123
10.

Oxidative stress and alcoholic liver disease.

Wu D, Cederbaum AI.

Semin Liver Dis. 2009 May;29(2):141-54. doi: 10.1055/s-0029-1214370. Epub 2009 Apr 22. Review.

PMID:
19387914
11.

Doxorubicin inactivates myocardial cytochrome c oxidase in rats: cardioprotection by Mito-Q.

Chandran K, Aggarwal D, Migrino RQ, Joseph J, McAllister D, Konorev EA, Antholine WE, Zielonka J, Srinivasan S, Avadhani NG, Kalyanaraman B.

Biophys J. 2009 Feb 18;96(4):1388-98. doi: 10.1016/j.bpj.2008.10.042.

12.

The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide-peptidoglycan model of sepsis.

Lowes DA, Thottakam BM, Webster NR, Murphy MP, Galley HF.

Free Radic Biol Med. 2008 Dec 1;45(11):1559-65. doi: 10.1016/j.freeradbiomed.2008.09.003. Epub 2008 Sep 17. Erratum in: Free Radic Biol Med. 2009 Oct 1;47(7):1098.

PMID:
18845241
13.

S-adenosyl-L-methionine co-administration prevents the ethanol-elicited dissociation of hepatic mitochondrial ribosomes in male rats.

Sykora P, Kharbanda KK, Crumm SE, Cahill A.

Alcohol Clin Exp Res. 2009 Jan;33(1):1-9. doi: 10.1111/j.1530-0277.2008.00803.x. Epub 2008 Sep 30.

14.

High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo.

Mantena SK, Vaughn DP, Andringa KK, Eccleston HB, King AL, Abrams GA, Doeller JE, Kraus DW, Darley-Usmar VM, Bailey SM.

Biochem J. 2009 Jan 1;417(1):183-93. doi: 10.1042/BJ20080868.

15.

Targeting lipophilic cations to mitochondria.

Murphy MP.

Biochim Biophys Acta. 2008 Jul-Aug;1777(7-8):1028-31. doi: 10.1016/j.bbabio.2008.03.029. Epub 2008 Apr 8. Review.

16.

Role and regulation of prolyl hydroxylase domain proteins.

Fong GH, Takeda K.

Cell Death Differ. 2008 Apr;15(4):635-41. doi: 10.1038/cdd.2008.10. Epub 2008 Feb 15. Review.

17.

CYP2E1 and oxidative liver injury by alcohol.

Lu Y, Cederbaum AI.

Free Radic Biol Med. 2008 Mar 1;44(5):723-38. Epub 2007 Nov 17. Review.

18.

Changes in the hepatic gene expression profile in a rat model of chronic ethanol treatment.

Park SH, Choi MS, Park T.

Food Chem Toxicol. 2008 Apr;46(4):1378-88. Epub 2007 Aug 29.

PMID:
17920746
19.

Novel interactions of mitochondria and reactive oxygen/nitrogen species in alcohol mediated liver disease.

Mantena SK, King AL, Andringa KK, Landar A, Darley-Usmar V, Bailey SM.

World J Gastroenterol. 2007 Oct 7;13(37):4967-73. Review.

20.

The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production.

Bell EL, Klimova TA, Eisenbart J, Moraes CT, Murphy MP, Budinger GR, Chandel NS.

J Cell Biol. 2007 Jun 18;177(6):1029-36. Epub 2007 Jun 11.

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