Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 43

1.

Identifying a high fraction of the human genome to be under selective constraint using GERP++.

Davydov EV, Goode DL, Sirota M, Cooper GM, Sidow A, Batzoglou S.

PLoS Comput Biol. 2010 Dec 2;6(12):e1001025. doi: 10.1371/journal.pcbi.1001025.

PMID:
21152010
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A map of human genome variation from population-scale sequencing.

1000 Genomes Project Consortium, Abecasis GR, Altshuler D, Auton A, Brooks LD, Durbin RM, Gibbs RA, Hurles ME, McVean GA.

Nature. 2010 Oct 28;467(7319):1061-73. doi: 10.1038/nature09534. Erratum in: Nature. 2011 May 26;473(7348):544. Xue, Yali [added]; Cartwright, Reed A [added]; Altshuler, David L [corrected to Altshuler, David]; Kebbel, Andrew [corrected to Keebler, Jonathan]; Koko-Gonzales, Paula [corrected to Kokko-Gonzales, Paula]; Nickerson, Debbie A [corrected to Nickerson, Deborah A].

PMID:
20981092
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Evidence that mutation is universally biased towards AT in bacteria.

Hershberg R, Petrov DA.

PLoS Genet. 2010 Sep 9;6(9):e1001115. doi: 10.1371/journal.pgen.1001115.

PMID:
20838599
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Evidence of selection upon genomic GC-content in bacteria.

Hildebrand F, Meyer A, Eyre-Walker A.

PLoS Genet. 2010 Sep 9;6(9):e1001107. doi: 10.1371/journal.pgen.1001107.

PMID:
20838593
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mutation-selection models of coding sequence evolution with site-heterogeneous amino acid fitness profiles.

Rodrigue N, Philippe H, Lartillot N.

Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4629-34. doi: 10.1073/pnas.0910915107. Epub 2010 Feb 22.

PMID:
20176949
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes.

Goode DL, Cooper GM, Schmutz J, Dickson M, Gonzales E, Tsai M, Karra K, Davydov E, Batzoglou S, Myers RM, Sidow A.

Genome Res. 2010 Mar;20(3):301-10. doi: 10.1101/gr.102210.109. Epub 2010 Jan 12.

PMID:
20067941
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The rate and molecular spectrum of spontaneous mutations in Arabidopsis thaliana.

Ossowski S, Schneeberger K, Lucas-Lledó JI, Warthmann N, Clark RM, Shaw RG, Weigel D, Lynch M.

Science. 2010 Jan 1;327(5961):92-4. doi: 10.1126/science.1180677.

PMID:
20044577
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Detection of nonneutral substitution rates on mammalian phylogenies.

Pollard KS, Hubisz MJ, Rosenbloom KR, Siepel A.

Genome Res. 2010 Jan;20(1):110-21. doi: 10.1101/gr.097857.109. Epub 2009 Oct 26.

PMID:
19858363
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Distributions of selectively constrained sites and deleterious mutation rates in the hominid and murid genomes.

Eory L, Halligan DL, Keightley PD.

Mol Biol Evol. 2010 Jan;27(1):177-92. doi: 10.1093/molbev/msp219. Epub .

PMID:
19759235
[PubMed - indexed for MEDLINE]
Free Article
10.

Biased gene conversion and the evolution of mammalian genomic landscapes.

Duret L, Galtier N.

Annu Rev Genomics Hum Genet. 2009;10:285-311. doi: 10.1146/annurev-genom-082908-150001. Review.

PMID:
19630562
[PubMed - indexed for MEDLINE]
11.

Comparative genomics of Drosophila mtDNA: Novel features of conservation and change across functional domains and lineages.

Montooth KL, Abt DN, Hofmann JW, Rand DM.

J Mol Evol. 2009 Jul;69(1):94-114. doi: 10.1007/s00239-009-9255-0. Epub 2009 Jun 16.

PMID:
19533212
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Measuring the rates of spontaneous mutation from deep and large-scale polymorphism data.

Messer PW.

Genetics. 2009 Aug;182(4):1219-32. doi: 10.1534/genetics.109.105692. Epub 2009 Jun 15.

PMID:
19528323
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Analysis of the genome sequences of three Drosophila melanogaster spontaneous mutation accumulation lines.

Keightley PD, Trivedi U, Thomson M, Oliver F, Kumar S, Blaxter ML.

Genome Res. 2009 Jul;19(7):1195-201. doi: 10.1101/gr.091231.109. Epub 2009 May 13.

PMID:
19439516
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Mutation patterns in the human genome: more variable than expected.

Duret L.

PLoS Biol. 2009 Feb 3;7(2):e1000028. doi: 10.1371/journal.pbio.1000028. No abstract available.

PMID:
19192948
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Hotspots of biased nucleotide substitutions in human genes.

Berglund J, Pollard KS, Webster MT.

PLoS Biol. 2009 Jan 27;7(1):e26. doi: 10.1371/journal.pbio.1000026.

PMID:
19175294
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The spectrum of mitochondrial mutation differs across species.

Montooth KL, Rand DM.

PLoS Biol. 2008 Aug 26;6(8):e213. doi: 10.1371/journal.pbio.0060213. No abstract available.

PMID:
18752353
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Direct estimation of the mitochondrial DNA mutation rate in Drosophila melanogaster.

Haag-Liautard C, Coffey N, Houle D, Lynch M, Charlesworth B, Keightley PD.

PLoS Biol. 2008 Aug 19;6(8):e204. doi: 10.1371/journal.pbio.0060204.

PMID:
18715119
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A genome-wide view of the spectrum of spontaneous mutations in yeast.

Lynch M, Sung W, Morris K, Coffey N, Landry CR, Dopman EB, Dickinson WJ, Okamoto K, Kulkarni S, Hartl DL, Thomas WK.

Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9272-7. doi: 10.1073/pnas.0803466105. Epub 2008 Jun 26.

PMID:
18583475
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The impact of recombination on nucleotide substitutions in the human genome.

Duret L, Arndt PF.

PLoS Genet. 2008 May 9;4(5):e1000071. doi: 10.1371/journal.pgen.1000071.

PMID:
18464896
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Mutation-selection models of codon substitution and their use to estimate selective strengths on codon usage.

Yang Z, Nielsen R.

Mol Biol Evol. 2008 Mar;25(3):568-79. doi: 10.1093/molbev/msm284. Epub 2008 Jan 3.

PMID:
18178545
[PubMed - indexed for MEDLINE]
Free Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk