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Items: 1 to 20 of 51

1.

AAV delivery of wild-type rhodopsin preserves retinal function in a mouse model of autosomal dominant retinitis pigmentosa.

Mao H, James T Jr, Schwein A, Shabashvili AE, Hauswirth WW, Gorbatyuk MS, Lewin AS.

Hum Gene Ther. 2011 May;22(5):567-75. doi: 10.1089/hum.2010.140. Epub 2011 Mar 7.

2.

Genome editing with engineered zinc finger nucleases.

Urnov FD, Rebar EJ, Holmes MC, Zhang HS, Gregory PD.

Nat Rev Genet. 2010 Sep;11(9):636-46. doi: 10.1038/nrg2842. Review.

PMID:
20717154
3.

Collaboration and competition between DNA double-strand break repair pathways.

Kass EM, Jasin M.

FEBS Lett. 2010 Sep 10;584(17):3703-8. doi: 10.1016/j.febslet.2010.07.057. Epub 2010 Aug 5. Review.

4.

Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases.

Meyer M, de Angelis MH, Wurst W, Kühn R.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15022-6. doi: 10.1073/pnas.1009424107. Epub 2010 Aug 4.

5.

Zinc-finger nucleases: new strategies to target the rat genome.

Geurts AM, Moreno C.

Clin Sci (Lond). 2010 Jul 6;119(8):303-11. doi: 10.1042/CS20100201. Review.

6.

Human CtIP mediates cell cycle control of DNA end resection and double strand break repair.

Huertas P, Jackson SP.

J Biol Chem. 2009 Apr 3;284(14):9558-65. doi: 10.1074/jbc.M808906200. Epub 2009 Feb 7.

7.

DNA repair deficiency and neurological disease.

McKinnon PJ.

Nat Rev Neurosci. 2009 Feb;10(2):100-12. doi: 10.1038/nrn2559. Epub 2009 Jan 15. Review. Erratum in: Nat Rev Neurosci. 2009 Mar;10(3):242.

8.

High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors.

Petrs-Silva H, Dinculescu A, Li Q, Min SH, Chiodo V, Pang JJ, Zhong L, Zolotukhin S, Srivastava A, Lewin AS, Hauswirth WW.

Mol Ther. 2009 Mar;17(3):463-71. doi: 10.1038/mt.2008.269. Epub 2008 Dec 16.

9.

Progress and prospects: zinc-finger nucleases as gene therapy agents.

Carroll D.

Gene Ther. 2008 Nov;15(22):1463-8. doi: 10.1038/gt.2008.145. Epub 2008 Sep 11. Review.

10.

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases.

Perez EE, Wang J, Miller JC, Jouvenot Y, Kim KA, Liu O, Wang N, Lee G, Bartsevich VV, Lee YL, Guschin DY, Rupniewski I, Waite AJ, Carpenito C, Carroll RG, Orange JS, Urnov FD, Rebar EJ, Ando D, Gregory PD, Riley JL, Holmes MC, June CH.

Nat Biotechnol. 2008 Jul;26(7):808-16. doi: 10.1038/nbt1410. Epub 2008 Jun 29.

11.

Knockout punches with a fistful of zinc fingers.

Wilson JH.

Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5653-4. doi: 10.1073/pnas.0802298105. Epub 2008 Apr 9. Review. No abstract available.

12.

Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases.

Santiago Y, Chan E, Liu PQ, Orlando S, Zhang L, Urnov FD, Holmes MC, Guschin D, Waite A, Miller JC, Rebar EJ, Gregory PD, Klug A, Collingwood TN.

Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5809-14. doi: 10.1073/pnas.0800940105. Epub 2008 Mar 21.

13.

The mechanism of human nonhomologous DNA end joining.

Lieber MR.

J Biol Chem. 2008 Jan 4;283(1):1-5. Epub 2007 Nov 12. Review.

14.

Human CtIP promotes DNA end resection.

Sartori AA, Lukas C, Coates J, Mistrik M, Fu S, Bartek J, Baer R, Lukas J, Jackson SP.

Nature. 2007 Nov 22;450(7169):509-14. Epub 2007 Oct 28.

15.

Defective DNA repair and neurodegenerative disease.

Rass U, Ahel I, West SC.

Cell. 2007 Sep 21;130(6):991-1004. Review.

16.

Novel adeno-associated virus serotypes efficiently transduce murine photoreceptors.

Allocca M, Mussolino C, Garcia-Hoyos M, Sanges D, Iodice C, Petrillo M, Vandenberghe LH, Wilson JM, Marigo V, Surace EM, Auricchio A.

J Virol. 2007 Oct;81(20):11372-80. Epub 2007 Aug 15.

17.

Age-related nonhomologous end joining activity in rat neurons.

Sharma S.

Brain Res Bull. 2007 Jun 15;73(1-3):48-54. Epub 2007 Feb 26.

PMID:
17499636
18.

Responding to DNA double strand breaks in the nervous system.

Lee Y, McKinnon PJ.

Neuroscience. 2007 Apr 14;145(4):1365-74. Epub 2006 Aug 23. Review.

PMID:
16934412
19.

DNA double-strand break repair: all's well that ends well.

Wyman C, Kanaar R.

Annu Rev Genet. 2006;40:363-83. Review.

PMID:
16895466
20.

Gene therapy restores vision-dependent behavior as well as retinal structure and function in a mouse model of RPE65 Leber congenital amaurosis.

Pang JJ, Chang B, Kumar A, Nusinowitz S, Noorwez SM, Li J, Rani A, Foster TC, Chiodo VA, Doyle T, Li H, Malhotra R, Teusner JT, McDowell JH, Min SH, Li Q, Kaushal S, Hauswirth WW.

Mol Ther. 2006 Mar;13(3):565-72. Epub 2005 Oct 11.

PMID:
16223604
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