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Cross-species infections of cultured cells by hepatitis E virus and discovery of an infectious virus-host recombinant.

Shukla P, Nguyen HT, Torian U, Engle RE, Faulk K, Dalton HR, Bendall RP, Keane FE, Purcell RH, Emerson SU.

Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2438-43. doi: 10.1073/pnas.1018878108. Epub 2011 Jan 24.


Structure of hepatitis E virion-sized particle reveals an RNA-dependent viral assembly pathway.

Xing L, Li TC, Mayazaki N, Simon MN, Wall JS, Moore M, Wang CY, Takeda N, Wakita T, Miyamura T, Cheng RH.

J Biol Chem. 2010 Oct 22;285(43):33175-83. doi: 10.1074/jbc.M110.106336. Epub 2010 Aug 18.


Release of genotype 1 hepatitis E virus from cultured hepatoma and polarized intestinal cells depends on open reading frame 3 protein and requires an intact PXXP motif.

Emerson SU, Nguyen HT, Torian U, Burke D, Engle R, Purcell RH.

J Virol. 2010 Sep;84(18):9059-69. doi: 10.1128/JVI.00593-10. Epub 2010 Jul 7.


Recent advances in Hepatitis E virus.

Meng XJ.

J Viral Hepat. 2010 Mar;17(3):153-61. doi: 10.1111/j.1365-2893.2009.01257.x. Epub 2009 Dec 21. Review.


Epidemiology of hepatitis E: current status.

Aggarwal R, Naik S.

J Gastroenterol Hepatol. 2009 Sep;24(9):1484-93. doi: 10.1111/j.1440-1746.2009.05933.x. Epub 2009 Aug 3. Review.


Development and characterization of a genotype 4 hepatitis E virus cell culture system using a HE-JF5/15F strain recovered from a fulminant hepatitis patient.

Tanaka T, Takahashi M, Takahashi H, Ichiyama K, Hoshino Y, Nagashima S, Mizuo H, Okamoto H.

J Clin Microbiol. 2009 Jun;47(6):1906-10. doi: 10.1128/JCM.00629-09. Epub 2009 Apr 15.


ORF3 protein of hepatitis E virus is essential for virion release from infected cells.

Yamada K, Takahashi M, Hoshino Y, Takahashi H, Ichiyama K, Nagashima S, Tanaka T, Okamoto H.

J Gen Virol. 2009 Aug;90(Pt 8):1880-91. doi: 10.1099/vir.0.010561-0. Epub 2009 Apr 1.


Molecular biology and pathogenesis of hepatitis E virus.

Chandra V, Taneja S, Kalia M, Jameel S.

J Biosci. 2008 Nov;33(4):451-64. Review.


Hepatitis E virus.

Khuroo MS, Khuroo MS.

Curr Opin Infect Dis. 2008 Oct;21(5):539-43. doi: 10.1097/QCO.0b013e32830ee08a. Review.


Hepatitis E and pregnancy: understanding the pathogenesis.

Navaneethan U, Al Mohajer M, Shata MT.

Liver Int. 2008 Nov;28(9):1190-9. doi: 10.1111/j.1478-3231.2008.01840.x. Epub 2008 Jul 25. Review.


Mutational events during the primary propagation and consecutive passages of hepatitis E virus strain JE03-1760F in cell culture.

Lorenzo FR, Tanaka T, Takahashi H, Ichiyama K, Hoshino Y, Yamada K, Inoue J, Takahashi M, Okamoto H.

Virus Res. 2008 Oct;137(1):86-96. doi: 10.1016/j.virusres.2008.06.005. Epub 2008 Jul 26.


ORF3 protein of hepatitis E virus is not required for replication, virion assembly, or infection of hepatoma cells in vitro.

Emerson SU, Nguyen H, Torian U, Purcell RH.

J Virol. 2006 Nov;80(21):10457-64. Epub 2006 Aug 23.


Inhibition of hepatitis B virus DNA replicative intermediate forms by recombinant interferon-gamma.

Parvez MK, Sehgal D, Sarin SK, Basir SF, Jameel S.

World J Gastroenterol. 2006 May 21;12(19):3006-14.


Essential elements of the capsid protein for self-assembly into empty virus-like particles of hepatitis E virus.

Li TC, Takeda N, Miyamura T, Matsuura Y, Wang JC, Engvall H, Hammar L, Xing L, Cheng RH.

J Virol. 2005 Oct;79(20):12999-3006.


In vitro replication of hepatitis E virus (HEV) genomes and of an HEV replicon expressing green fluorescent protein.

Emerson SU, Nguyen H, Graff J, Stephany DA, Brockington A, Purcell RH.

J Virol. 2004 May;78(9):4838-46.


Structural characterization of recombinant hepatitis E virus ORF2 proteins in baculovirus-infected insect cells.

Robinson RA, Burgess WH, Emerson SU, Leibowitz RS, Sosnovtseva SA, Tsarev S, Purcell RH.

Protein Expr Purif. 1998 Feb;12(1):75-84.


Expression in animal cells and characterization of the hepatitis E virus structural proteins.

Jameel S, Zafrullah M, Ozdener MH, Panda SK.

J Virol. 1996 Jan;70(1):207-16.


Hepatitis viruses: changing patterns of human disease.

Purcell RH.

Proc Natl Acad Sci U S A. 1994 Mar 29;91(7):2401-6. Review. Erratum in: Proc Natl Acad Sci U S A 1994 Sep 13;91(19):9195.


Isolation of a cDNA from the virus responsible for enterically transmitted non-A, non-B hepatitis.

Reyes GR, Purdy MA, Kim JP, Luk KC, Young LM, Fry KE, Bradley DW.

Science. 1990 Mar 16;247(4948):1335-9.

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