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Results: 1 to 20 of 41

References for PMC Articles for PubMed (Select 21458670)

1.

BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program.

Ren D, Tu HC, Kim H, Wang GX, Bean GR, Takeuchi O, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH.

Science. 2010 Dec 3;330(6009):1390-3. doi: 10.1126/science.1190217.

2.

BH3-triggered structural reorganization drives the activation of proapoptotic BAX.

Gavathiotis E, Reyna DE, Davis ML, Bird GH, Walensky LD.

Mol Cell. 2010 Nov 12;40(3):481-92. doi: 10.1016/j.molcel.2010.10.019.

3.

The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation.

Shen ZJ, Esnault S, Schinzel A, Borner C, Malter JS.

Nat Immunol. 2009 Mar;10(3):257-65. doi: 10.1038/ni.1697. Epub 2009 Feb 1.

4.

Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax.

Lovell JF, Billen LP, Bindner S, Shamas-Din A, Fradin C, Leber B, Andrews DW.

Cell. 2008 Dec 12;135(6):1074-84. doi: 10.1016/j.cell.2008.11.010.

5.

Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax.

Fletcher JI, Meusburger S, Hawkins CJ, Riglar DT, Lee EF, Fairlie WD, Huang DC, Adams JM.

Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18081-7. doi: 10.1073/pnas.0808691105. Epub 2008 Nov 3. Erratum in: Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1678.

6.

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

Chipuk JE, Green DR.

Trends Cell Biol. 2008 Apr;18(4):157-64. doi: 10.1016/j.tcb.2008.01.007. Epub 2008 Mar 7. Review.

7.

The BCL-2 protein family: opposing activities that mediate cell death.

Youle RJ, Strasser A.

Nat Rev Mol Cell Biol. 2008 Jan;9(1):47-59. Review.

PMID:
18097445
8.
9.

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.

Willis SN, Fletcher JI, Kaufmann T, van Delft MF, Chen L, Czabotar PE, Ierino H, Lee EF, Fairlie WD, Bouillet P, Strasser A, Kluck RM, Adams JM, Huang DC.

Science. 2007 Feb 9;315(5813):856-9.

10.

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.

Kim H, Rafiuddin-Shah M, Tu HC, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH.

Nat Cell Biol. 2006 Dec;8(12):1348-58. Epub 2006 Nov 19.

PMID:
17115033
11.

A stapled BID BH3 helix directly binds and activates BAX.

Walensky LD, Pitter K, Morash J, Oh KJ, Barbuto S, Fisher J, Smith E, Verdine GL, Korsmeyer SJ.

Mol Cell. 2006 Oct 20;24(2):199-210.

12.

Bcl-2 changes conformation to inhibit Bax oligomerization.

Dlugosz PJ, Billen LP, Annis MG, Zhu W, Zhang Z, Lin J, Leber B, Andrews DW.

EMBO J. 2006 Jun 7;25(11):2287-96. Epub 2006 Apr 27.

13.

An inhibitor of Bcl-2 family proteins induces regression of solid tumours.

Oltersdorf T, Elmore SW, Shoemaker AR, Armstrong RC, Augeri DJ, Belli BA, Bruncko M, Deckwerth TL, Dinges J, Hajduk PJ, Joseph MK, Kitada S, Korsmeyer SJ, Kunzer AR, Letai A, Li C, Mitten MJ, Nettesheim DG, Ng S, Nimmer PM, O'Connor JM, Oleksijew A, Petros AM, Reed JC, Shen W, Tahir SK, Thompson CB, Tomaselli KJ, Wang B, Wendt MD, Zhang H, Fesik SW, Rosenberg SH.

Nature. 2005 Jun 2;435(7042):677-81. Epub 2005 May 15.

14.

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.

Willis SN, Chen L, Dewson G, Wei A, Naik E, Fletcher JI, Adams JM, Huang DC.

Genes Dev. 2005 Jun 1;19(11):1294-305. Epub 2005 May 18.

15.

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.

Kuwana T, Bouchier-Hayes L, Chipuk JE, Bonzon C, Sullivan BA, Green DR, Newmeyer DD.

Mol Cell. 2005 Feb 18;17(4):525-35.

PMID:
15721256
16.

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function.

Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG, Colman PM, Day CL, Adams JM, Huang DC.

Mol Cell. 2005 Feb 4;17(3):393-403.

PMID:
15694340
17.

Monitoring disulfide bond formation in the eukaryotic cytosol.

Ƙstergaard H, Tachibana C, Winther JR.

J Cell Biol. 2004 Aug 2;166(3):337-45. Epub 2004 Jul 26.

18.

Cytomegalovirus cell death suppressor vMIA blocks Bax- but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria.

Arnoult D, Bartle LM, Skaletskaya A, Poncet D, Zamzami N, Park PU, Sharpe J, Youle RJ, Goldmacher VS.

Proc Natl Acad Sci U S A. 2004 May 25;101(21):7988-93. Epub 2004 May 17.

19.

Bcl-x(L) sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers.

Jeong SY, Gaume B, Lee YJ, Hsu YT, Ryu SW, Yoon SH, Youle RJ.

EMBO J. 2004 May 19;23(10):2146-55. Epub 2004 May 6.

20.
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