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Items: 1 to 20 of 62

1.

A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage.

Chou DM, Adamson B, Dephoure NE, Tan X, Nottke AC, Hurov KE, Gygi SP, Colaiácovo MP, Elledge SJ.

Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18475-80. doi: 10.1073/pnas.1012946107. Epub 2010 Oct 11.

2.

BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair.

Ismail IH, Andrin C, McDonald D, Hendzel MJ.

J Cell Biol. 2010 Oct 4;191(1):45-60. doi: 10.1083/jcb.201003034.

3.

BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery.

Facchino S, Abdouh M, Chatoo W, Bernier G.

J Neurosci. 2010 Jul 28;30(30):10096-111. doi: 10.1523/JNEUROSCI.1634-10.2010.

4.

ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks.

Shanbhag NM, Rafalska-Metcalf IU, Balane-Bolivar C, Janicki SM, Greenberg RA.

Cell. 2010 Jun 11;141(6):970-81. doi: 10.1016/j.cell.2010.04.038.

5.

The E3 ubiquitin-ligase Bmi1/Ring1A controls the proteasomal degradation of Top2alpha cleavage complex - a potentially new drug target.

Alchanati I, Teicher C, Cohen G, Shemesh V, Barr HM, Nakache P, Ben-Avraham D, Idelevich A, Angel I, Livnah N, Tuvia S, Reiss Y, Taglicht D, Erez O.

PLoS One. 2009 Dec 1;4(12):e8104. doi: 10.1371/journal.pone.0008104.

6.

The ubiquitin landscape at DNA double-strand breaks.

Messick TE, Greenberg RA.

J Cell Biol. 2009 Nov 2;187(3):319-26. doi: 10.1083/jcb.200908074. Review.

7.

Modifying chromatin architecture during the response to DNA breakage.

Venkitaraman AR.

Crit Rev Biochem Mol Biol. 2010 Feb;45(1):2-13. doi: 10.3109/10409230903325446. Review.

PMID:
19874211
8.

Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response.

Marteijn JA, Bekker-Jensen S, Mailand N, Lans H, Schwertman P, Gourdin AM, Dantuma NP, Lukas J, Vermeulen W.

J Cell Biol. 2009 Sep 21;186(6):835-47. doi: 10.1083/jcb.200902150.

9.

Mechanisms of polycomb gene silencing: knowns and unknowns.

Simon JA, Kingston RE.

Nat Rev Mol Cell Biol. 2009 Oct;10(10):697-708. doi: 10.1038/nrm2763. Epub 2009 Sep 9. Review.

PMID:
19738629
10.

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases.

Hockemeyer D, Soldner F, Beard C, Gao Q, Mitalipova M, DeKelver RC, Katibah GE, Amora R, Boydston EA, Zeitler B, Meng X, Miller JC, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Jaenisch R.

Nat Biotechnol. 2009 Sep;27(9):851-7. doi: 10.1038/nbt.1562. Epub 2009 Aug 13.

11.

Genome-wide uH2A localization analysis highlights Bmi1-dependent deposition of the mark at repressed genes.

Kallin EM, Cao R, Jothi R, Xia K, Cui K, Zhao K, Zhang Y.

PLoS Genet. 2009 Jun;5(6):e1000506. doi: 10.1371/journal.pgen.1000506. Epub 2009 Jun 5.

12.

Heterochromatin protein 1 is recruited to various types of DNA damage.

Luijsterburg MS, Dinant C, Lans H, Stap J, Wiernasz E, Lagerwerf S, Warmerdam DO, Lindh M, Brink MC, Dobrucki JW, Aten JA, Fousteri MI, Jansen G, Dantuma NP, Vermeulen W, Mullenders LH, Houtsmuller AB, Verschure PJ, van Driel R.

J Cell Biol. 2009 May 18;185(4):577-86. doi: 10.1083/jcb.200810035.

13.

Bmi1 regulates mitochondrial function and the DNA damage response pathway.

Liu J, Cao L, Chen J, Song S, Lee IH, Quijano C, Liu H, Keyvanfar K, Chen H, Cao LY, Ahn BH, Kumar NG, Rovira II, Xu XL, van Lohuizen M, Motoyama N, Deng CX, Finkel T.

Nature. 2009 May 21;459(7245):387-92. doi: 10.1038/nature08040. Epub 2009 Apr 29.

14.

Solving the RIDDLE of 53BP1 recruitment to sites of damage.

Stewart GS.

Cell Cycle. 2009 May 15;8(10):1532-8. Epub 2009 May 4. Review.

PMID:
19372751
15.

MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks.

Shao G, Patterson-Fortin J, Messick TE, Feng D, Shanbhag N, Wang Y, Greenberg RA.

Genes Dev. 2009 Mar 15;23(6):740-54. doi: 10.1101/gad.1739609. Epub 2009 Mar 4.

16.

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.

Doil C, Mailand N, Bekker-Jensen S, Menard P, Larsen DH, Pepperkok R, Ellenberg J, Panier S, Durocher D, Bartek J, Lukas J, Lukas C.

Cell. 2009 Feb 6;136(3):435-46. doi: 10.1016/j.cell.2008.12.041.

17.

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.

Stewart GS, Panier S, Townsend K, Al-Hakim AK, Kolas NK, Miller ES, Nakada S, Ylanko J, Olivarius S, Mendez M, Oldreive C, Wildenhain J, Tagliaferro A, Pelletier L, Taubenheim N, Durandy A, Byrd PJ, Stankovic T, Taylor AM, Durocher D.

Cell. 2009 Feb 6;136(3):420-34. doi: 10.1016/j.cell.2008.12.042.

18.

The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubc13-dependent ubiquitination events at DNA double strand breaks.

Shao G, Lilli DR, Patterson-Fortin J, Coleman KA, Morrissey DE, Greenberg RA.

Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3166-71. doi: 10.1073/pnas.0807485106. Epub 2009 Feb 6.

19.

Chromatin restoration following nucleotide excision repair involves the incorporation of ubiquitinated H2A at damaged genomic sites.

Zhu Q, Wani G, Arab HH, El-Mahdy MA, Ray A, Wani AA.

DNA Repair (Amst). 2009 Feb 1;8(2):262-73. doi: 10.1016/j.dnarep.2008.11.007. Epub 2008 Dec 20.

20.

Histone ubiquitination associates with BRCA1-dependent DNA damage response.

Wu J, Huen MS, Lu LY, Ye L, Dou Y, Ljungman M, Chen J, Yu X.

Mol Cell Biol. 2009 Feb;29(3):849-60. doi: 10.1128/MCB.01302-08. Epub 2008 Nov 17.

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