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Results: 1 to 20 of 69

1.

Transcriptional regulation of renal cytoprotective genes by Nrf2 and its potential use as a therapeutic target to mitigate cisplatin-induced nephrotoxicity.

Aleksunes LM, Goedken MJ, Rockwell CE, Thomale J, Manautou JE, Klaassen CD.

J Pharmacol Exp Ther. 2010 Oct;335(1):2-12. doi: 10.1124/jpet.110.170084. Epub 2010 Jul 6.

PMID:
20605904
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies.

Vaidya VS, Ozer JS, Dieterle F, Collings FB, Ramirez V, Troth S, Muniappa N, Thudium D, Gerhold D, Holder DJ, Bobadilla NA, Marrer E, Perentes E, Cordier A, Vonderscher J, Maurer G, Goering PL, Sistare FD, Bonventre JV.

Nat Biotechnol. 2010 May;28(5):478-85. doi: 10.1038/nbt.1623.

PMID:
20458318
[PubMed - indexed for MEDLINE]
Free PMC Article
3.
4.

Acute kidney injury: a springboard for progression in chronic kidney disease.

Venkatachalam MA, Griffin KA, Lan R, Geng H, Saikumar P, Bidani AK.

Am J Physiol Renal Physiol. 2010 May;298(5):F1078-94. doi: 10.1152/ajprenal.00017.2010. Epub 2010 Mar 3. Review.

PMID:
20200097
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mechanisms of cell protection by heme oxygenase-1.

Gozzelino R, Jeney V, Soares MP.

Annu Rev Pharmacol Toxicol. 2010;50:323-54. doi: 10.1146/annurev.pharmtox.010909.105600. Review.

PMID:
20055707
[PubMed - indexed for MEDLINE]
6.

Preexisting chronic kidney disease: a potential for improved outcomes from acute kidney injury.

Khosla N, Soroko SB, Chertow GM, Himmelfarb J, Ikizler TA, Paganini E, Mehta RL; Program to Improve Care in Acute Renal Disease (PICARD).

Clin J Am Soc Nephrol. 2009 Dec;4(12):1914-9. doi: 10.2215/CJN.01690309. Epub 2009 Nov 25.

PMID:
19965524
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Immunoregulatory effects of HO-1: how does it work?

Soares MP, Marguti I, Cunha A, Larsen R.

Curr Opin Pharmacol. 2009 Aug;9(4):482-9. doi: 10.1016/j.coph.2009.05.008. Epub 2009 Jul 6. Review.

PMID:
19586801
[PubMed - indexed for MEDLINE]
8.

Human haem oxygenase-1 induction by nitro-linoleic acid is mediated by cAMP, AP-1 and E-box response element interactions.

Wright MM, Kim J, Hock TD, Leitinger N, Freeman BA, Agarwal A.

Biochem J. 2009 Aug 13;422(2):353-61. doi: 10.1042/BJ20090339.

PMID:
19534727
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice.

Liu M, Grigoryev DN, Crow MT, Haas M, Yamamoto M, Reddy SP, Rabb H.

Kidney Int. 2009 Aug;76(3):277-85. doi: 10.1038/ki.2009.157. Epub 2009 May 13.

PMID:
19436334
[PubMed - indexed for MEDLINE]
10.

Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice.

Yates MS, Tran QT, Dolan PM, Osburn WO, Shin S, McCulloch CC, Silkworth JB, Taguchi K, Yamamoto M, Williams CR, Liby KT, Sporn MB, Sutter TR, Kensler TW.

Carcinogenesis. 2009 Jun;30(6):1024-31. doi: 10.1093/carcin/bgp100. Epub 2009 Apr 21.

PMID:
19386581
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease.

Morse D, Lin L, Choi AM, Ryter SW.

Free Radic Biol Med. 2009 Jul 1;47(1):1-12. doi: 10.1016/j.freeradbiomed.2009.04.007. Epub 2009 Apr 9. Review.

PMID:
19362144
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Long-term outcomes after acute kidney injury: where we stand and how we can move forward.

Lo L, Liu KD, Hsu CY.

Am J Kidney Dis. 2009 Jun;53(6):928-31. doi: 10.1053/j.ajkd.2009.02.003. Epub 2009 Mar 21. No abstract available.

PMID:
19303684
[PubMed - indexed for MEDLINE]
13.

The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress.

Nguyen T, Nioi P, Pickett CB.

J Biol Chem. 2009 May 15;284(20):13291-5. doi: 10.1074/jbc.R900010200. Epub 2009 Jan 30. Review.

PMID:
19182219
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Heme oxygenase and renal disease.

Jarmi T, Agarwal A.

Curr Hypertens Rep. 2009 Feb;11(1):56-62. Review.

PMID:
19146802
[PubMed - indexed for MEDLINE]
15.

PPARgamma and its ligands: therapeutic implications in cardiovascular disease.

Villacorta L, Schopfer FJ, Zhang J, Freeman BA, Chen YE.

Clin Sci (Lond). 2009 Feb;116(3):205-18. doi: 10.1042/CS20080195. Review.

PMID:
19118492
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors.

Hong C, Tontonoz P.

Curr Opin Genet Dev. 2008 Oct;18(5):461-7. doi: 10.1016/j.gde.2008.07.016. Epub 2008 Sep 7. Review.

PMID:
18782619
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

KLF2 primes the antioxidant transcription factor Nrf2 for activation in endothelial cells.

Fledderus JO, Boon RA, Volger OL, Hurttila H, Ylä-Herttuala S, Pannekoek H, Levonen AL, Horrevoets AJ.

Arterioscler Thromb Vasc Biol. 2008 Jul;28(7):1339-46. doi: 10.1161/ATVBAHA.108.165811. Epub 2008 May 8.

PMID:
18467642
[PubMed - indexed for MEDLINE]
Free Article
18.

Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme.

Yoon HY, Kang NI, Lee HK, Jang KY, Park JW, Park BH.

Biochem Pharmacol. 2008 Jun 1;75(11):2214-23. doi: 10.1016/j.bcp.2008.02.029. Epub 2008 Mar 4.

PMID:
18407246
[PubMed - indexed for MEDLINE]
19.

The risk of acute renal failure in patients with chronic kidney disease.

Hsu CY, Ordoñez JD, Chertow GM, Fan D, McCulloch CE, Go AS.

Kidney Int. 2008 Jul;74(1):101-7. doi: 10.1038/ki.2008.107. Epub 2008 Apr 2.

PMID:
18385668
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Activation of cerebral peroxisome proliferator-activated receptors gamma exerts neuroprotection by inhibiting oxidative stress following pilocarpine-induced status epilepticus.

Yu X, Shao XG, Sun H, Li YN, Yang J, Deng YC, Huang YG.

Brain Res. 2008 Mar 20;1200:146-58. doi: 10.1016/j.brainres.2008.01.047. Epub 2008 Jan 26.

PMID:
18289512
[PubMed - indexed for MEDLINE]

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