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Results: 1 to 20 of 39

1.

Role of CYP2A5 in the clearance of nicotine and cotinine: insights from studies on a Cyp2a5-null mouse model.

Zhou X, Zhuo X, Xie F, Kluetzman K, Shu YZ, Humphreys WG, Ding X.

J Pharmacol Exp Ther. 2010 Feb;332(2):578-87. doi: 10.1124/jpet.109.162610. Epub 2009 Nov 18.

PMID:
19923441
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

High abundance of testosterone and salivary androgen-binding protein in the lateral nasal gland of male mice.

Zhou X, Zhang X, Weng Y, Fang C, Kaminsky L, Ding X.

J Steroid Biochem Mol Biol. 2009 Oct;117(1-3):81-6. doi: 10.1016/j.jsbmb.2009.06.002. Epub 2009 Jun 11.

PMID:
19524040
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Sex-dependent disposition of acetaminophen sulfate and glucuronide in the in situ perfused mouse liver.

Lee JK, Abe K, Bridges AS, Patel NJ, Raub TJ, Pollack GM, Brouwer KL.

Drug Metab Dispos. 2009 Sep;37(9):1916-21. doi: 10.1124/dmd.109.026815. Epub 2009 Jun 1.

PMID:
19487254
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Rapid bursts of androgen-binding protein (Abp) gene duplication occurred independently in diverse mammals.

Laukaitis CM, Heger A, Blakley TD, Munclinger P, Ponting CP, Karn RC.

BMC Evol Biol. 2008 Feb 12;8:46. doi: 10.1186/1471-2148-8-46.

PMID:
18269759
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Expression of cytochrome p450 and other biotransformation genes in fetal and adult human nasal mucosa.

Zhang X, Zhang QY, Liu D, Su T, Weng Y, Ling G, Chen Y, Gu J, Schilling B, Ding X.

Drug Metab Dispos. 2005 Oct;33(10):1423-8. Epub 2005 Jul 13.

PMID:
16014766
[PubMed - indexed for MEDLINE]
Free Article
7.

Contribution of acetaminophen-cysteine to acetaminophen nephrotoxicity II. Possible involvement of the gamma-glutamyl cycle.

Stern ST, Bruno MK, Horton RA, Hill DW, Roberts JC, Cohen SD.

Toxicol Appl Pharmacol. 2005 Jan 15;202(2):160-71.

PMID:
15629191
[PubMed - indexed for MEDLINE]
8.

Contribution of acetaminophen-cysteine to acetaminophen nephrotoxicity in CD-1 mice: I. Enhancement of acetaminophen nephrotoxicity by acetaminophen-cysteine.

Stern ST, Bruno MK, Hennig GE, Horton RA, Roberts JC, Cohen SD.

Toxicol Appl Pharmacol. 2005 Jan 15;202(2):151-9.

PMID:
15629190
[PubMed - indexed for MEDLINE]
9.

Effects of 8-methoxypsoralen on cytochrome P450 2A13.

von Weymarn LB, Zhang QY, Ding X, Hollenberg PF.

Carcinogenesis. 2005 Mar;26(3):621-9. Epub 2004 Dec 3.

PMID:
15579482
[PubMed - indexed for MEDLINE]
Free Article
10.

Acetaminophen-induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition.

Hinson JA, Reid AB, McCullough SS, James LP.

Drug Metab Rev. 2004 Oct;36(3-4):805-22. Review.

PMID:
15554248
[PubMed - indexed for MEDLINE]
11.

In vivo mechanisms of tissue-selective drug toxicity: effects of liver-specific knockout of the NADPH-cytochrome P450 reductase gene on acetaminophen toxicity in kidney, lung, and nasal mucosa.

Gu J, Cui H, Behr M, Zhang L, Zhang QY, Yang W, Hinson JA, Ding X.

Mol Pharmacol. 2005 Mar;67(3):623-30. Epub 2004 Nov 18.

PMID:
15550675
[PubMed - indexed for MEDLINE]
Free Article
12.

Regulation of the cytochrome P450 2A genes.

Su T, Ding X.

Toxicol Appl Pharmacol. 2004 Sep 15;199(3):285-94. Review.

PMID:
15364544
[PubMed - indexed for MEDLINE]
13.

Targeted disruption of the olfactory mucosa-specific Cyp2g1 gene: impact on acetaminophen toxicity in the lateral nasal gland, and tissue-selective effects on Cyp2a5 expression.

Zhuo X, Gu J, Behr MJ, Swiatek PJ, Cui H, Zhang QY, Xie Y, Collins DN, Ding X.

J Pharmacol Exp Ther. 2004 Feb;308(2):719-28. Epub 2003 Nov 10.

PMID:
14610229
[PubMed - indexed for MEDLINE]
Free Article
14.

Cell-specific expression of CYP2A5 in the mouse respiratory tract: effects of olfactory toxicants.

Piras E, Franzén A, Fernández EL, Bergström U, Raffalli-Mathieu F, Lang M, Brittebo EB.

J Histochem Cytochem. 2003 Nov;51(11):1545-55.

PMID:
14566026
[PubMed - indexed for MEDLINE]
Free PMC Article
15.
16.

Hepatobiliary excretion of acetaminophen glutathione conjugate and its derivatives in transport-deficient (TR-) hyperbilirubinemic rats.

Chen C, Hennig GE, Manautou JE.

Drug Metab Dispos. 2003 Jun;31(6):798-804.

PMID:
12756215
[PubMed - indexed for MEDLINE]
Free Article
17.

Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation.

Wada R, Tifft CJ, Proia RL.

Proc Natl Acad Sci U S A. 2000 Sep 26;97(20):10954-9.

PMID:
11005868
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs.

Wijnholds J, Mol CA, van Deemter L, de Haas M, Scheffer GL, Baas F, Beijnen JH, Scheper RJ, Hatse S, De Clercq E, Balzarini J, Borst P.

Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7476-81.

PMID:
10840050
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Cytochrome P450 and steroid hydroxylase activity in mouse olfactory and vomeronasal mucosa.

Gu J, Dudley C, Su T, Spink DC, Zhang QY, Moss RL, Ding X.

Biochem Biophys Res Commun. 1999 Dec 9;266(1):262-7.

PMID:
10581200
[PubMed - indexed for MEDLINE]
20.

Role of CYP1A2 in the hepatotoxicity of acetaminophen: investigations using Cyp1a2 null mice.

Tonge RP, Kelly EJ, Bruschi SA, Kalhorn T, Eaton DL, Nebert DW, Nelson SD.

Toxicol Appl Pharmacol. 1998 Nov;153(1):102-8.

PMID:
9875304
[PubMed - indexed for MEDLINE]
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