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Items: 1 to 20 of 52

1.

Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase.

DuPage M, Dooley AL, Jacks T.

Nat Protoc. 2009;4(7):1064-72. doi: 10.1038/nprot.2009.95. Epub 2009 Jun 25.

2.

Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion.

Bucks CM, Norton JA, Boesteanu AC, Mueller YM, Katsikis PD.

J Immunol. 2009 Jun 1;182(11):6697-708. doi: 10.4049/jimmunol.0800997.

3.

High antigen levels are the cause of T cell exhaustion during chronic viral infection.

Mueller SN, Ahmed R.

Proc Natl Acad Sci U S A. 2009 May 26;106(21):8623-8. doi: 10.1073/pnas.0809818106. Epub 2009 May 11.

4.

Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies.

Pellegrini M, Calzascia T, Elford AR, Shahinian A, Lin AE, Dissanayake D, Dhanji S, Nguyen LT, Gronski MA, Morre M, Assouline B, Lahl K, Sparwasser T, Ohashi PS, Mak TW.

Nat Med. 2009 May;15(5):528-36. doi: 10.1038/nm.1953. Epub 2009 Apr 26. Erratum in: Nat Med. 2009 Jul;15(7):819.

PMID:
19396174
5.

Tumor recognition and self-recognition induce distinct transcriptional profiles in antigen-specific CD4 T cells.

Getnet D, Maris CH, Hipkiss EL, Grosso JF, Harris TJ, Yen HR, Bruno TC, Wada S, Adler A, Georgantas RW, Jie C, Goldberg MV, Pardoll DM, Drake CG.

J Immunol. 2009 Apr 15;182(8):4675-85. doi: 10.4049/jimmunol.0803400.

6.

Regulated expression of a tumor-associated antigen reveals multiple levels of T-cell tolerance in a mouse model of lung cancer.

Cheung AF, Dupage MJ, Dong HK, Chen J, Jacks T.

Cancer Res. 2008 Nov 15;68(22):9459-68. doi: 10.1158/0008-5472.CAN-08-2634.

7.

Somatic mutations affect key pathways in lung adenocarcinoma.

Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, Cibulskis K, Sougnez C, Greulich H, Muzny DM, Morgan MB, Fulton L, Fulton RS, Zhang Q, Wendl MC, Lawrence MS, Larson DE, Chen K, Dooling DJ, Sabo A, Hawes AC, Shen H, Jhangiani SN, Lewis LR, Hall O, Zhu Y, Mathew T, Ren Y, Yao J, Scherer SE, Clerc K, Metcalf GA, Ng B, Milosavljevic A, Gonzalez-Garay ML, Osborne JR, Meyer R, Shi X, Tang Y, Koboldt DC, Lin L, Abbott R, Miner TL, Pohl C, Fewell G, Haipek C, Schmidt H, Dunford-Shore BH, Kraja A, Crosby SD, Sawyer CS, Vickery T, Sander S, Robinson J, Winckler W, Baldwin J, Chirieac LR, Dutt A, Fennell T, Hanna M, Johnson BE, Onofrio RC, Thomas RK, Tonon G, Weir BA, Zhao X, Ziaugra L, Zody MC, Giordano T, Orringer MB, Roth JA, Spitz MR, Wistuba II, Ozenberger B, Good PJ, Chang AC, Beer DG, Watson MA, Ladanyi M, Broderick S, Yoshizawa A, Travis WD, Pao W, Province MA, Weinstock GM, Varmus HE, Gabriel SB, Lander ES, Gibbs RA, Meyerson M, Wilson RK.

Nature. 2008 Oct 23;455(7216):1069-75. doi: 10.1038/nature07423.

8.

Rapid tolerization of virus-activated tumor-specific CD8+ T cells in prostate tumors of TRAMP mice.

Bai A, Higham E, Eisen HN, Wittrup KD, Chen J.

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13003-8. doi: 10.1073/pnas.0805599105. Epub 2008 Aug 22.

9.

Immunological weapons acquired early in life win battles with cancer late in life.

Finn OJ.

J Immunol. 2008 Aug 1;181(3):1589-92. No abstract available.

10.

TNFR1 signaling and IFN-gamma signaling determine whether T cells induce tumor dormancy or promote multistage carcinogenesis.

Müller-Hermelink N, Braumüller H, Pichler B, Wieder T, Mailhammer R, Schaak K, Ghoreschi K, Yazdi A, Haubner R, Sander CA, Mocikat R, Schwaiger M, Förster I, Huss R, Weber WA, Kneilling M, Röcken M.

Cancer Cell. 2008 Jun;13(6):507-18. doi: 10.1016/j.ccr.2008.04.001.

11.

Stromal gene expression predicts clinical outcome in breast cancer.

Finak G, Bertos N, Pepin F, Sadekova S, Souleimanova M, Zhao H, Chen H, Omeroglu G, Meterissian S, Omeroglu A, Hallett M, Park M.

Nat Med. 2008 May;14(5):518-27. doi: 10.1038/nm1764. Epub 2008 Apr 27.

PMID:
18438415
12.

T-cell quality in memory and protection: implications for vaccine design.

Seder RA, Darrah PA, Roederer M.

Nat Rev Immunol. 2008 Apr;8(4):247-58. doi: 10.1038/nri2274. Epub 2008 Mar 7. Review. Erratum in: Nat Rev Immunol. 2008 Jun;8(6):486.

PMID:
18323851
13.

Epitope landscape in breast and colorectal cancer.

Segal NH, Parsons DW, Peggs KS, Velculescu V, Kinzler KW, Vogelstein B, Allison JP.

Cancer Res. 2008 Feb 1;68(3):889-92. doi: 10.1158/0008-5472.CAN-07-3095.

14.

Recognition of a ubiquitous self antigen by prostate cancer-infiltrating CD8+ T lymphocytes.

Savage PA, Vosseller K, Kang C, Larimore K, Riedel E, Wojnoonski K, Jungbluth AA, Allison JP.

Science. 2008 Jan 11;319(5860):215-20. doi: 10.1126/science.1148886.

15.

Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy.

Buckanovich RJ, Facciabene A, Kim S, Benencia F, Sasaroli D, Balint K, Katsaros D, O'Brien-Jenkins A, Gimotty PA, Coukos G.

Nat Med. 2008 Jan;14(1):28-36. Epub 2008 Jan 6.

PMID:
18157142
16.

Adaptive immunity maintains occult cancer in an equilibrium state.

Koebel CM, Vermi W, Swann JB, Zerafa N, Rodig SJ, Old LJ, Smyth MJ, Schreiber RD.

Nature. 2007 Dec 6;450(7171):903-7. Epub 2007 Nov 18.

PMID:
18026089
17.

TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice.

Calzascia T, Pellegrini M, Hall H, Sabbagh L, Ono N, Elford AR, Mak TW, Ohashi PS.

J Clin Invest. 2007 Dec;117(12):3833-45.

18.

Molecular signature of CD8+ T cell exhaustion during chronic viral infection.

Wherry EJ, Ha SJ, Kaech SM, Haining WN, Sarkar S, Kalia V, Subramaniam S, Blattman JN, Barber DL, Ahmed R.

Immunity. 2007 Oct;27(4):670-84. Epub 2007 Oct 18. Erratum in: Immunity. 2007 Nov;27(5):824.

19.

Dynamics of the immune reaction to pancreatic cancer from inception to invasion.

Clark CE, Hingorani SR, Mick R, Combs C, Tuveson DA, Vonderheide RH.

Cancer Res. 2007 Oct 1;67(19):9518-27.

20.

Maximizing mouse cancer models.

Frese KK, Tuveson DA.

Nat Rev Cancer. 2007 Sep;7(9):645-58. Review.

PMID:
17687385
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