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References for PMC Articles for PubMed (Select 21214544)


DNA-PKcs controls an endosomal signaling pathway for a proinflammatory response by natural killer cells.

Rajagopalan S, Moyle MW, Joosten I, Long EO.

Sci Signal. 2010 Feb 23;3(110):ra14. doi: 10.1126/scisignal.2000467.


A novel KIR-associated function: evidence that CpG DNA uptake and shuttling to early endosomes is mediated by KIR3DL2.

Sivori S, Falco M, Carlomagno S, Romeo E, Soldani C, Bensussan A, Viola A, Moretta L, Moretta A.

Blood. 2010 Sep 9;116(10):1637-47. doi: 10.1182/blood-2009-12-256586. Epub 2010 Feb 10.


A small, variable, and irregular killer cell Ig-like receptor locus accompanies the absence of MHC-C and MHC-G in gibbons.

Abi-Rached L, Kuhl H, Roos C, ten Hallers B, Zhu B, Carbone L, de Jong PJ, Mootnick AR, Knaust F, Reinhardt R, Parham P, Walter L.

J Immunol. 2010 Feb 1;184(3):1379-91. doi: 10.4049/jimmunol.0903016. Epub 2009 Dec 21.


Natural killer cells and cancer: regulation by the killer cell Ig-like receptors (KIR).

Purdy AK, Campbell KS.

Cancer Biol Ther. 2009 Dec;8(23):2211-20. Epub 2009 Dec 28. Review.


SHP-2 expression negatively regulates NK cell function.

Purdy AK, Campbell KS.

J Immunol. 2009 Dec 1;183(11):7234-43. doi: 10.4049/jimmunol.0900088. Epub 2009 Nov 13.


IPD--the Immuno Polymorphism Database.

Robinson J, Mistry K, McWilliam H, Lopez R, Marsh SG.

Nucleic Acids Res. 2010 Jan;38(Database issue):D863-9. doi: 10.1093/nar/gkp879. Epub 2009 Oct 29.


KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C.

Graef T, Moesta AK, Norman PJ, Abi-Rached L, Vago L, Older Aguilar AM, Gleimer M, Hammond JA, Guethlein LA, Bushnell DA, Robinson PJ, Parham P.

J Exp Med. 2009 Oct 26;206(11):2557-72. doi: 10.1084/jem.20091010.


Dimorphic motifs in D0 and D1+D2 domains of killer cell Ig-like receptor 3DL1 combine to form receptors with high, moderate, and no avidity for the complex of a peptide derived from HIV and HLA-A*2402.

Sharma D, Bastard K, Guethlein LA, Norman PJ, Yawata N, Yawata M, Pando M, Thananchai H, Dong T, Rowland-Jones S, Brodsky FM, Parham P.

J Immunol. 2009 Oct 1;183(7):4569-82. doi: 10.4049/jimmunol.0901734. Epub 2009 Sep 14.


Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes.

Norman PJ, Abi-Rached L, Gendzekhadze K, Hammond JA, Moesta AK, Sharma D, Graef T, McQueen KL, Guethlein LA, Carrington CV, Chandanayingyong D, Chang YH, Crespí C, Saruhan-Direskeneli G, Hameed K, Kamkamidze G, Koram KA, Layrisse Z, Matamoros N, Milà J, Park MH, Pitchappan RM, Ramdath DD, Shiau MY, Stephens HA, Struik S, Tyan D, Verity DH, Vaughan RW, Davis RW, Fraser PA, Riley EM, Ronaghi M, Parham P.

Genome Res. 2009 May;19(5):757-69. doi: 10.1101/gr.085738.108.


HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection.

Alter G, Rihn S, Walter K, Nolting A, Martin M, Rosenberg ES, Miller JS, Carrington M, Altfeld M.

J Virol. 2009 Jul;83(13):6798-805. doi: 10.1128/JVI.00256-09. Epub 2009 Apr 22.


NK cell education: not an on-off switch but a tunable rheostat.

Brodin P, Kärre K, Höglund P.

Trends Immunol. 2009 Apr;30(4):143-9. doi: 10.1016/ Epub 2009 Mar 11.


Evolution and survival of marine carnivores did not require a diversity of killer cell Ig-like receptors or Ly49 NK cell receptors.

Hammond JA, Guethlein LA, Abi-Rached L, Moesta AK, Parham P.

J Immunol. 2009 Mar 15;182(6):3618-27. doi: 10.4049/jimmunol.0803026.


Genetic control of variegated KIR gene expression: polymorphisms of the bi-directional KIR3DL1 promoter are associated with distinct frequencies of gene expression.

Li H, Pascal V, Martin MP, Carrington M, Anderson SK.

PLoS Genet. 2008 Nov;4(11):e1000254. doi: 10.1371/journal.pgen.1000254. Epub 2008 Nov 14.


Dramatically reduced surface expression of NK cell receptor KIR2DS3 is attributed to multiple residues throughout the molecule.

VandenBussche CJ, Mulrooney TJ, Frazier WR, Dakshanamurthy S, Hurley CK.

Genes Immun. 2009 Mar;10(2):162-73. doi: 10.1038/gene.2008.91. Epub 2008 Nov 13.


Extracellular domain alterations impact surface expression of stimulatory natural killer cell receptor KIR2DS5.

Steiner NK, Dakshanamurthy S, VandenBussche CJ, Hurley CK.

Immunogenetics. 2008 Nov;60(11):655-67. doi: 10.1007/s00251-008-0322-2. Epub 2008 Aug 6.


Human natural killer cells.

Caligiuri MA.

Blood. 2008 Aug 1;112(3):461-9. doi: 10.1182/blood-2007-09-077438. Review.


Evidence that the KIR2DS5 gene codes for a surface receptor triggering natural killer cell function.

Della Chiesa M, Romeo E, Falco M, Balsamo M, Augugliaro R, Moretta L, Bottino C, Moretta A, Vitale M.

Eur J Immunol. 2008 Aug;38(8):2284-9. doi: 10.1002/eji.200838434.


Evolution of the Ly49 and Nkrp1 recognition systems.

Carlyle JR, Mesci A, Fine JH, Chen P, Bélanger S, Tai LH, Makrigiannis AP.

Semin Immunol. 2008 Dec;20(6):321-30. doi: 10.1016/j.smim.2008.05.004. Epub 2008 Jul 2. Review.


Novel KIR3DL1 alleles and their expression levels on NK cells: convergent evolution of KIR3DL1 phenotype variation?

Thomas R, Yamada E, Alter G, Martin MP, Bashirova AA, Norman PJ, Altfeld M, Parham P, Anderson SK, McVicar DW, Carrington M.

J Immunol. 2008 May 15;180(10):6743-50.


Synergistic polymorphism at two positions distal to the ligand-binding site makes KIR2DL2 a stronger receptor for HLA-C than KIR2DL3.

Moesta AK, Norman PJ, Yawata M, Yawata N, Gleimer M, Parham P.

J Immunol. 2008 Mar 15;180(6):3969-79.

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