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Items: 1 to 20 of 37


Mice deficient in the serine/threonine protein kinase VRK1 are infertile due to a progressive loss of spermatogonia.

Wiebe MS, Nichols RJ, Molitor TP, Lindgren JK, Traktman P.

Biol Reprod. 2010 Jan;82(1):182-93. doi: 10.1095/biolreprod.109.079095. Epub 2009 Aug 19.


Protein kinase VRK-1 regulates cell invasion and EGL-17/FGF signaling in Caenorhabditis elegans.

Klerkx EP, Alarcón P, Waters K, Reinke V, Sternberg PW, Askjaer P.

Dev Biol. 2009 Nov 1;335(1):12-21. doi: 10.1016/j.ydbio.2009.08.007. Epub 2009 Aug 11.


The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse.

Zheng K, Wu X, Kaestner KH, Wang PJ.

BMC Dev Biol. 2009 Jun 29;9:38. doi: 10.1186/1471-213X-9-38.


Emerging biological functions of the vaccinia-related kinase (VRK) family.

Klerkx EP, Lazo PA, Askjaer P.

Histol Histopathol. 2009 Jun;24(6):749-59. Review.


Structure of the pseudokinase VRK3 reveals a degraded catalytic site, a highly conserved kinase fold, and a putative regulatory binding site.

Scheeff ED, Eswaran J, Bunkoczi G, Knapp S, Manning G.

Structure. 2009 Jan 14;17(1):128-38. doi: 10.1016/j.str.2008.10.018.


Mouse period 2 mRNA circadian oscillation is modulated by PTB-mediated rhythmic mRNA degradation.

Woo KC, Kim TD, Lee KH, Kim DY, Kim W, Lee KY, Kim KT.

Nucleic Acids Res. 2009 Jan;37(1):26-37. doi: 10.1093/nar/gkn893. Epub 2008 Nov 14.


VRK1 phosphorylates CREB and mediates CCND1 expression.

Kang TH, Park DY, Kim W, Kim KT.

J Cell Sci. 2008 Sep 15;121(Pt 18):3035-41. doi: 10.1242/jcs.026757. Epub 2008 Aug 19.


Regulation of spermatogonial stem cell self-renewal in mammals.

Oatley JM, Brinster RL.

Annu Rev Cell Dev Biol. 2008;24:263-86. doi: 10.1146/annurev.cellbio.24.110707.175355. Review.


Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell-cycle arrest.

Takubo K, Ohmura M, Azuma M, Nagamatsu G, Yamada W, Arai F, Hirao A, Suda T.

Cell Stem Cell. 2008 Feb 7;2(2):170-82. doi: 10.1016/j.stem.2007.10.023.


Human VRK1 is an early response gene and its loss causes a block in cell cycle progression.

Valbuena A, López-Sánchez I, Lazo PA.

PLoS One. 2008 Feb 20;3(2):e1642. doi: 10.1371/journal.pone.0001642.


Mitotic histone H3 phosphorylation by vaccinia-related kinase 1 in mammalian cells.

Kang TH, Park DY, Choi YH, Kim KJ, Yoon HS, Kim KT.

Mol Cell Biol. 2007 Dec;27(24):8533-46. Epub 2007 Oct 15.


Identification of a dominant epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations.

Valbuena A, López-Sánchez I, Vega FM, Sevilla A, Sanz-García M, Blanco S, Lazo PA.

Arch Biochem Biophys. 2007 Sep 1;465(1):219-26. Epub 2007 Jun 14.


Spermatogonial stem cells.

Oatley JM, Brinster RL.

Methods Enzymol. 2006;419:259-82. Review.


VRK1 signaling pathway in the context of the proliferation phenotype in head and neck squamous cell carcinoma.

Santos CR, Rodríguez-Pinilla M, Vega FM, Rodríguez-Peralto JL, Blanco S, Sevilla A, Valbuena A, Hernández T, van Wijnen AJ, Li F, de Alava E, Sánchez-Céspedes M, Lazo PA.

Mol Cancer Res. 2006 Mar;4(3):177-85.


A histone code in meiosis: the histone kinase, NHK-1, is required for proper chromosomal architecture in Drosophila oocytes.

Ivanovska I, Khandan T, Ito T, Orr-Weaver TL.

Genes Dev. 2005 Nov 1;19(21):2571-82. Epub 2005 Oct 17.


Maintenance of spermatogenesis requires TAF4b, a gonad-specific subunit of TFIID.

Falender AE, Freiman RN, Geles KG, Lo KC, Hwang K, Lamb DJ, Morris PL, Tjian R, Richards JS.

Genes Dev. 2005 Apr 1;19(7):794-803. Epub 2005 Mar 17.


p53 Stabilization and accumulation induced by human vaccinia-related kinase 1.

Vega FM, Sevilla A, Lazo PA.

Mol Cell Biol. 2004 Dec;24(23):10366-80.


c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK).

Sevilla A, Santos CR, Barcia R, Vega FM, Lazo PA.

Oncogene. 2004 Nov 25;23(55):8950-8.

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