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Results: 1 to 20 of 57

1.

Treatment of castration-resistant prostate cancer: updates on therapeutics targeting the androgen receptor signaling pathway.

Zhu W, Zhu DS, Madan RA, Gulley JL, Figg WD, Dahut WL.

Am J Ther. 2010 Mar-Apr;17(2):176-81. doi: 10.1097/MJT.0b013e3181c6c0b2. Review.

PMID:
20019584
[PubMed - indexed for MEDLINE]
2.

miR-21: an androgen receptor-regulated microRNA that promotes hormone-dependent and hormone-independent prostate cancer growth.

Ribas J, Ni X, Haffner M, Wentzel EA, Salmasi AH, Chowdhury WH, Kudrolli TA, Yegnasubramanian S, Luo J, Rodriguez R, Mendell JT, Lupold SE.

Cancer Res. 2009 Sep 15;69(18):7165-9. doi: 10.1158/0008-5472.CAN-09-1448. Epub 2009 Sep 8.

PMID:
19738047
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation.

Lee KH, Chen YL, Yeh SD, Hsiao M, Lin JT, Goan YG, Lu PJ.

Oncogene. 2009 Sep 24;28(38):3360-70. doi: 10.1038/onc.2009.192. Epub 2009 Jul 13.

PMID:
19597470
[PubMed - indexed for MEDLINE]
4.

Tea polyphenols decrease serum levels of prostate-specific antigen, hepatocyte growth factor, and vascular endothelial growth factor in prostate cancer patients and inhibit production of hepatocyte growth factor and vascular endothelial growth factor in vitro.

McLarty J, Bigelow RL, Smith M, Elmajian D, Ankem M, Cardelli JA.

Cancer Prev Res (Phila). 2009 Jul;2(7):673-82. doi: 10.1158/1940-6207.CAPR-08-0167. Epub 2009 Jun 19.

PMID:
19542190
[PubMed - indexed for MEDLINE]
5.

Cancer statistics, 2009.

Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ.

CA Cancer J Clin. 2009 Jul-Aug;59(4):225-49. doi: 10.3322/caac.20006. Epub 2009 May 27.

PMID:
19474385
[PubMed - indexed for MEDLINE]
Free Article
6.

Suppression of androgen receptor signaling and prostate specific antigen expression by (-)-epigallocatechin-3-gallate in different progression stages of LNCaP prostate cancer cells.

Chuu CP, Chen RY, Kokontis JM, Hiipakka RA, Liao S.

Cancer Lett. 2009 Mar 8;275(1):86-92. doi: 10.1016/j.canlet.2008.10.001. Epub 2008 Nov 1.

PMID:
18977589
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A novel dietary flavonoid fisetin inhibits androgen receptor signaling and tumor growth in athymic nude mice.

Khan N, Asim M, Afaq F, Abu Zaid M, Mukhtar H.

Cancer Res. 2008 Oct 15;68(20):8555-63. doi: 10.1158/0008-5472.CAN-08-0240.

PMID:
18922931
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Genomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancer.

Ambs S, Prueitt RL, Yi M, Hudson RS, Howe TM, Petrocca F, Wallace TA, Liu CG, Volinia S, Calin GA, Yfantis HG, Stephens RM, Croce CM.

Cancer Res. 2008 Aug 1;68(15):6162-70. doi: 10.1158/0008-5472.CAN-08-0144.

PMID:
18676839
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Targeting the androgen receptor pathway in prostate cancer.

Chen Y, Sawyers CL, Scher HI.

Curr Opin Pharmacol. 2008 Aug;8(4):440-8. doi: 10.1016/j.coph.2008.07.005. Epub 2008 Aug 12. Review.

PMID:
18674639
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The contribution of different androgen receptor domains to receptor dimerization and signaling.

Centenera MM, Harris JM, Tilley WD, Butler LM.

Mol Endocrinol. 2008 Nov;22(11):2373-82. doi: 10.1210/me.2008-0017. Epub 2008 Jul 10. Review.

PMID:
18617596
[PubMed - indexed for MEDLINE]
11.

Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance.

Dehm SM, Schmidt LJ, Heemers HV, Vessella RL, Tindall DJ.

Cancer Res. 2008 Jul 1;68(13):5469-77. doi: 10.1158/0008-5472.CAN-08-0594.

PMID:
18593950
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Suppression of NFkappaB and its regulated gene products by oral administration of green tea polyphenols in an autochthonous mouse prostate cancer model.

Siddiqui IA, Shukla Y, Adhami VM, Sarfaraz S, Asim M, Hafeez BB, Mukhtar H.

Pharm Res. 2008 Sep;25(9):2135-42. doi: 10.1007/s11095-008-9553-z. Epub 2008 Mar 4.

PMID:
18317887
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Src kinase potentiates androgen receptor transactivation function and invasion of androgen-independent prostate cancer C4-2 cells.

Asim M, Siddiqui IA, Hafeez BB, Baniahmad A, Mukhtar H.

Oncogene. 2008 Jun 5;27(25):3596-604. doi: 10.1038/sj.onc.1211016. Epub 2008 Jan 28.

PMID:
18223692
[PubMed - indexed for MEDLINE]
14.

Green tea polyphenol EGCG sensitizes human prostate carcinoma LNCaP cells to TRAIL-mediated apoptosis and synergistically inhibits biomarkers associated with angiogenesis and metastasis.

Siddiqui IA, Malik A, Adhami VM, Asim M, Hafeez BB, Sarfaraz S, Mukhtar H.

Oncogene. 2008 Mar 27;27(14):2055-63. Epub 2007 Nov 12.

PMID:
17998943
[PubMed - indexed for MEDLINE]
15.

Widespread deregulation of microRNA expression in human prostate cancer.

Ozen M, Creighton CJ, Ozdemir M, Ittmann M.

Oncogene. 2008 Mar 13;27(12):1788-93. Epub 2007 Sep 24.

PMID:
17891175
[PubMed - indexed for MEDLINE]
16.

Structural characterization of the human androgen receptor ligand-binding domain complexed with EM5744, a rationally designed steroidal ligand bearing a bulky chain directed toward helix 12.

Cantin L, Faucher F, Couture JF, de Jésus-Tran KP, Legrand P, Ciobanu LC, Fréchette Y, Labrecque R, Singh SM, Labrie F, Breton R.

J Biol Chem. 2007 Oct 19;282(42):30910-9. Epub 2007 Aug 21.

PMID:
17711855
[PubMed - indexed for MEDLINE]
Free Article
17.

MicroRNA expression profiling in prostate cancer.

Porkka KP, Pfeiffer MJ, Waltering KK, Vessella RL, Tammela TL, Visakorpi T.

Cancer Res. 2007 Jul 1;67(13):6130-5.

PMID:
17616669
[PubMed - indexed for MEDLINE]
Free Article
18.

Epigallocatechin-3-gallate and bicalutamide cause growth arrest and apoptosis in NRP-152 and NRP-154 prostate epithelial cells.

Morrissey C, Brown M, O'Sullivan J, Weathered N, Watson RW, Tenniswood M.

Int J Urol. 2007 Jun;14(6):545-51.

PMID:
17593102
[PubMed - indexed for MEDLINE]
19.

Combined inhibitory effects of green tea polyphenols and selective cyclooxygenase-2 inhibitors on the growth of human prostate cancer cells both in vitro and in vivo.

Adhami VM, Malik A, Zaman N, Sarfaraz S, Siddiqui IA, Syed DN, Afaq F, Pasha FS, Saleem M, Mukhtar H.

Clin Cancer Res. 2007 Mar 1;13(5):1611-9.

PMID:
17332308
[PubMed - indexed for MEDLINE]
Free Article
20.

The androgen receptor T877A mutant recruits LXXLL and FXXLF peptides differently than wild-type androgen receptor in a time-resolved fluorescence resonance energy transfer assay.

Ozers MS, Marks BD, Gowda K, Kupcho KR, Ervin KM, De Rosier T, Qadir N, Eliason HC, Riddle SM, Shekhani MS.

Biochemistry. 2007 Jan 23;46(3):683-95.

PMID:
17223690
[PubMed - indexed for MEDLINE]
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