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Results: 1 to 20 of 39

1.

Recent advances in the photochemical control of protein function.

Riggsbee CW, Deiters A.

Trends Biotechnol. 2010 Sep;28(9):468-75. doi: 10.1016/j.tibtech.2010.06.001. Epub 2010 Jul 29. Review.

PMID:
20667607
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Engineered allosteric activation of kinases in living cells.

Karginov AV, Ding F, Kota P, Dokholyan NV, Hahn KM.

Nat Biotechnol. 2010 Jul;28(7):743-7. doi: 10.1038/nbt.1639. Epub 2010 Jun 27.

PMID:
20581846
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A collection of caged compounds for probing roles of local translation in neurobiology.

Sadovski O, Jaikaran AS, Samanta S, Fabian MR, Dowling RJ, Sonenberg N, Woolley GA.

Bioorg Med Chem. 2010 Nov 15;18(22):7746-52. doi: 10.1016/j.bmc.2010.04.005. Epub 2010 Apr 7.

PMID:
20427189
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Light-activated gene expression directs segregation of co-cultured cells in vitro.

Sauers DJ, Temburni MK, Biggins JB, Ceo LM, Galileo DS, Koh JT.

ACS Chem Biol. 2010 Mar 19;5(3):313-20. doi: 10.1021/cb9002305.

PMID:
20050613
[PubMed - indexed for MEDLINE]
5.

Hybrid inhibitors of phosphatidylinositol 3-kinase (PI3K) and the mammalian target of rapamycin (mTOR): design, synthesis, and superior antitumor activity of novel wortmannin-rapamycin conjugates.

Ayral-Kaloustian S, Gu J, Lucas J, Cinque M, Gaydos C, Zask A, Chaudhary I, Wang J, Di L, Young M, Ruppen M, Mansour TS, Gibbons JJ, Yu K.

J Med Chem. 2010 Jan 14;53(1):452-9. doi: 10.1021/jm901427g.

PMID:
19928864
[PubMed - indexed for MEDLINE]
6.

Principles and applications of the photochemical control of cellular processes.

Deiters A.

Chembiochem. 2010 Jan 4;11(1):47-53. doi: 10.1002/cbic.200900529. No abstract available.

PMID:
19911402
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Light activation as a method of regulating and studying gene expression.

Deiters A.

Curr Opin Chem Biol. 2009 Dec;13(5-6):678-86. doi: 10.1016/j.cbpa.2009.09.026. Epub 2009 Oct 24. Review.

PMID:
19857985
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Doxycycline-dependent photoactivated gene expression in eukaryotic systems.

Cambridge SB, Geissler D, Calegari F, Anastassiadis K, Hasan MT, Stewart AF, Huttner WB, Hagen V, Bonhoeffer T.

Nat Methods. 2009 Jul;6(7):527-31. doi: 10.1038/nmeth.1340. Epub 2009 Jun 7.

PMID:
19503080
[PubMed - indexed for MEDLINE]
9.

Illuminating the chemistry of life: design, synthesis, and applications of "caged" and related photoresponsive compounds.

Lee HM, Larson DR, Lawrence DS.

ACS Chem Biol. 2009 Jun 19;4(6):409-27. doi: 10.1021/cb900036s. Review.

PMID:
19298086
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Light-activation of gene function in mammalian cells via ribozymes.

Young DD, Garner RA, Yoder JA, Deiters A.

Chem Commun (Camb). 2009 Feb 7;(5):568-70. doi: 10.1039/b819375d. Epub 2008 Dec 2.

PMID:
19283293
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Paxillin comes of age.

Deakin NO, Turner CE.

J Cell Sci. 2008 Aug 1;121(Pt 15):2435-44. doi: 10.1242/jcs.018044. Review.

PMID:
18650496
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Ab initio folding of proteins with all-atom discrete molecular dynamics.

Ding F, Tsao D, Nie H, Dokholyan NV.

Structure. 2008 Jul;16(7):1010-8. doi: 10.1016/j.str.2008.03.013.

PMID:
18611374
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Photobiological effects of UVA and UVB light in zebrafish embryos: evidence for a competent photorepair system.

Dong Q, Svoboda K, Tiersch TR, Monroe WT.

J Photochem Photobiol B. 2007 Sep 25;88(2-3):137-46. Epub 2007 Jul 21.

PMID:
17716904
[PubMed - indexed for MEDLINE]
14.

A directed approach for engineering conditional protein stability using biologically silent small molecules.

Maynard-Smith LA, Chen LC, Banaszynski LA, Ooi AG, Wandless TJ.

J Biol Chem. 2007 Aug 24;282(34):24866-72. Epub 2007 Jul 1.

PMID:
17603093
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Photochemical activation of protein expression in bacterial cells.

Young DD, Deiters A.

Angew Chem Int Ed Engl. 2007;46(23):4290-2. No abstract available.

PMID:
17458846
[PubMed - indexed for MEDLINE]
16.

Photochemical control of biological processes.

Young DD, Deiters A.

Org Biomol Chem. 2007 Apr 7;5(7):999-1005. Epub 2006 Dec 20. Review.

PMID:
17377650
[PubMed - indexed for MEDLINE]
17.

The rapamycin-binding domain of the protein kinase mammalian target of rapamycin is a destabilizing domain.

Edwards SR, Wandless TJ.

J Biol Chem. 2007 May 4;282(18):13395-401. Epub 2007 Mar 9.

PMID:
17350953
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Regulating gene expression with light-activated oligonucleotides.

Tang X, Dmochowski IJ.

Mol Biosyst. 2007 Feb;3(2):100-10. Epub 2006 Nov 20. Review.

PMID:
17245489
[PubMed - indexed for MEDLINE]
19.

Biologically active molecules with a "light switch".

Mayer G, Heckel A.

Angew Chem Int Ed Engl. 2006 Jul 24;45(30):4900-21. Review.

PMID:
16826610
[PubMed - indexed for MEDLINE]
20.

Rapamycin analogs with differential binding specificity permit orthogonal control of protein activity.

Bayle JH, Grimley JS, Stankunas K, Gestwicki JE, Wandless TJ, Crabtree GR.

Chem Biol. 2006 Jan;13(1):99-107.

PMID:
16426976
[PubMed - indexed for MEDLINE]
Free Article

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