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Results: 1 to 20 of 62

1.

Receptor tyrosine kinase transmembrane domains: Function, dimer structure and dimerization energetics.

Li E, Hristova K.

Cell Adh Migr. 2010 Apr-Jun;4(2):249-54. Epub 2010 Apr 23. Review.

PMID:
20168077
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Measuring the energetics of membrane protein dimerization in mammalian membranes.

Chen L, Novicky L, Merzlyakov M, Hristov T, Hristova K.

J Am Chem Soc. 2010 Mar 17;132(10):3628-35. doi: 10.1021/ja910692u.

PMID:
20158179
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The single transmembrane domains of human receptor tyrosine kinases encode self-interactions.

Finger C, Escher C, Schneider D.

Sci Signal. 2009 Sep 22;2(89):ra56. doi: 10.1126/scisignal.2000547.

PMID:
19797273
[PubMed - indexed for MEDLINE]
Free Article
4.

Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment.

Jura N, Endres NF, Engel K, Deindl S, Das R, Lamers MH, Wemmer DE, Zhang X, Kuriyan J.

Cell. 2009 Jun 26;137(7):1293-307. doi: 10.1016/j.cell.2009.04.025. Erratum in: Cell. 2009 Aug 7;138(3):604.

PMID:
19563760
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Energetics of ErbB1 transmembrane domain dimerization in lipid bilayers.

Chen L, Merzlyakov M, Cohen T, Shai Y, Hristova K.

Biophys J. 2009 Jun 3;96(11):4622-30. doi: 10.1016/j.bpj.2009.03.004.

PMID:
19486684
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

HER-2 signaling and inhibition in breast cancer.

Browne BC, O'Brien N, Duffy MJ, Crown J, O'Donovan N.

Curr Cancer Drug Targets. 2009 May;9(3):419-38. Review.

PMID:
19442060
[PubMed - indexed for MEDLINE]
7.

Two GxxxG-like motifs facilitate promiscuous interactions of the human ErbB transmembrane domains.

Escher C, Cymer F, Schneider D.

J Mol Biol. 2009 May 29;389(1):10-6. doi: 10.1016/j.jmb.2009.04.002. Epub 2009 Apr 8.

PMID:
19361517
[PubMed - indexed for MEDLINE]
8.

The HER-2 receptor and breast cancer: ten years of targeted anti-HER-2 therapy and personalized medicine.

Ross JS, Slodkowska EA, Symmans WF, Pusztai L, Ravdin PM, Hortobagyi GN.

Oncologist. 2009 Apr;14(4):320-68. doi: 10.1634/theoncologist.2008-0230. Epub 2009 Apr 3. Review.

PMID:
19346299
[PubMed - indexed for MEDLINE]
Free Article
9.

Forster resonance energy transfer measurements of transmembrane helix dimerization energetics.

Merzlyakov M, Hristova K.

Methods Enzymol. 2008;450:107-27. doi: 10.1016/S0076-6879(08)03406-X.

PMID:
19152858
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Pathogenic activation of receptor tyrosine kinases in mammalian membranes.

He L, Hristova K.

J Mol Biol. 2008 Dec 31;384(5):1130-42. doi: 10.1016/j.jmb.2008.10.036. Epub 2008 Oct 19.

PMID:
18976668
[PubMed - indexed for MEDLINE]
11.

All EGF(ErbB) receptors have preformed homo- and heterodimeric structures in living cells.

Tao RH, Maruyama IN.

J Cell Sci. 2008 Oct 1;121(Pt 19):3207-17. doi: 10.1242/jcs.033399. Epub 2008 Sep 9.

PMID:
18782861
[PubMed - indexed for MEDLINE]
Free Article
12.

Quantitative measurements of protein interactions in a crowded cellular environment.

Li E, Placone J, Merzlyakov M, Hristova K.

Anal Chem. 2008 Aug 1;80(15):5976-85. doi: 10.1021/ac800616u. Epub 2008 Jul 3.

PMID:
18597478
[PubMed - indexed for MEDLINE]
13.

Transmembrane domain of EphA1 receptor forms dimers in membrane-like environment.

Artemenko EO, Egorova NS, Arseniev AS, Feofanov AV.

Biochim Biophys Acta. 2008 Oct;1778(10):2361-7. doi: 10.1016/j.bbamem.2008.06.003. Epub 2008 Jun 11.

PMID:
18590698
[PubMed - indexed for MEDLINE]
Free Article
14.

A simple "proximity" correction for Förster resonance energy transfer efficiency determination in membranes using lifetime measurements.

Posokhov YO, Merzlyakov M, Hristova K, Ladokhin AS.

Anal Biochem. 2008 Sep 1;380(1):134-6. doi: 10.1016/j.ab.2008.05.041. Epub 2008 Jun 16.

PMID:
18559252
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Effect of pathogenic cysteine mutations on FGFR3 transmembrane domain dimerization in detergents and lipid bilayers.

You M, Spangler J, Li E, Han X, Ghosh P, Hristova K.

Biochemistry. 2007 Oct 2;46(39):11039-46. Epub 2007 Sep 11.

PMID:
17845056
[PubMed - indexed for MEDLINE]
16.

Achondroplasia.

Horton WA, Hall JG, Hecht JT.

Lancet. 2007 Jul 14;370(9582):162-72. Review.

PMID:
17630040
[PubMed - indexed for MEDLINE]
17.

Pertuzumab, a novel HER dimerization inhibitor, inhibits the growth of human lung cancer cells mediated by the HER3 signaling pathway.

Sakai K, Yokote H, Murakami-Murofushi K, Tamura T, Saijo N, Nishio K.

Cancer Sci. 2007 Sep;98(9):1498-503. Epub 2007 Jul 11.

PMID:
17627612
[PubMed - indexed for MEDLINE]
18.

Studies of receptor tyrosine kinase transmembrane domain interactions: the EmEx-FRET method.

Merzlyakov M, Chen L, Hristova K.

J Membr Biol. 2007 Feb;215(2-3):93-103. Epub 2007 Jun 14.

PMID:
17565424
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

ErbB receptors: new insights on mechanisms and biology.

Linggi B, Carpenter G.

Trends Cell Biol. 2006 Dec;16(12):649-56. Epub 2006 Nov 7. Review.

PMID:
17085050
[PubMed - indexed for MEDLINE]
20.

Quantitative understanding of the energy transfer between fluorescent proteins connected via flexible peptide linkers.

Evers TH, van Dongen EM, Faesen AC, Meijer EW, Merkx M.

Biochemistry. 2006 Nov 7;45(44):13183-92.

PMID:
17073440
[PubMed - indexed for MEDLINE]

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