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Results: 1 to 20 of 55

1.

A large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complex.

Jackson LP, Kelly BT, McCoy AJ, Gaffry T, James LC, Collins BM, Höning S, Evans PR, Owen DJ.

Cell. 2010 Jun 25;141(7):1220-9. doi: 10.1016/j.cell.2010.05.006.

PMID:
20603002
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Disruption of the murine Ap2β1 gene causes nonsyndromic cleft palate.

Li W, Puertollano R, Bonifacino JS, Overbeek PA, Everett ET.

Cleft Palate Craniofac J. 2010 Nov;47(6):566-73. doi: 10.1597/09-145. Epub 2010 Mar 2.

PMID:
20500056
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

AP-1/sigma1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory.

Glyvuk N, Tsytsyura Y, Geumann C, D'Hooge R, Hüve J, Kratzke M, Baltes J, Boening D, Klingauf J, Schu P.

EMBO J. 2010 Apr 21;29(8):1318-30. doi: 10.1038/emboj.2010.15. Epub 2010 Mar 4. Erratum in: EMBO J. 2010 Jun 2;29(11):1941. Böning, Daniel [corrected to Boening, Daniel].

PMID:
20203623
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis.

Delevoye C, Hurbain I, Tenza D, Sibarita JB, Uzan-Gafsou S, Ohno H, Geerts WJ, Verkleij AJ, Salamero J, Marks MS, Raposo G.

J Cell Biol. 2009 Oct 19;187(2):247-64. doi: 10.1083/jcb.200907122.

PMID:
19841138
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Tickets to ride: selecting cargo for clathrin-regulated internalization.

Traub LM.

Nat Rev Mol Cell Biol. 2009 Sep;10(9):583-96. doi: 10.1038/nrm2751. Review.

PMID:
19696796
[PubMed - indexed for MEDLINE]
6.

A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex.

Kelly BT, McCoy AJ, Späte K, Miller SE, Evans PR, Höning S, Owen DJ.

Nature. 2008 Dec 18;456(7224):976-79. doi: 10.1038/nature07422. No abstract available.

PMID:
19140243
[PubMed - indexed for MEDLINE]
7.

A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex.

Chaudhuri R, Mattera R, Lindwasser OW, Robinson MS, Bonifacino JS.

J Virol. 2009 Mar;83(6):2518-30. doi: 10.1128/JVI.02227-08. Epub 2009 Jan 7.

PMID:
19129443
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Disruption of AP1S1, causing a novel neurocutaneous syndrome, perturbs development of the skin and spinal cord.

Montpetit A, Côté S, Brustein E, Drouin CA, Lapointe L, Boudreau M, Meloche C, Drouin R, Hudson TJ, Drapeau P, Cossette P.

PLoS Genet. 2008 Dec;4(12):e1000296. doi: 10.1371/journal.pgen.1000296. Epub 2008 Dec 5.

PMID:
19057675
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Sorting of lysosomal proteins.

Braulke T, Bonifacino JS.

Biochim Biophys Acta. 2009 Apr;1793(4):605-14. doi: 10.1016/j.bbamcr.2008.10.016. Epub 2008 Nov 12. Review.

PMID:
19046998
[PubMed - indexed for MEDLINE]
Free Article
10.

The AP-2 adaptor beta2 appendage scaffolds alternate cargo endocytosis.

Keyel PA, Thieman JR, Roth R, Erkan E, Everett ET, Watkins SC, Heuser JE, Traub LM.

Mol Biol Cell. 2008 Dec;19(12):5309-26. doi: 10.1091/mbc.E08-07-0712. Epub 2008 Oct 8.

PMID:
18843039
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Clinical, cellular, and neuropathological consequences of AP1S2 mutations: further delineation of a recognizable X-linked mental retardation syndrome.

Borck G, Mollà-Herman A, Boddaert N, Encha-Razavi F, Philippe A, Robel L, Desguerre I, Brunelle F, Benmerah A, Munnich A, Colleaux L.

Hum Mutat. 2008 Jul;29(7):966-74. doi: 10.1002/humu.20531.

PMID:
18428203
[PubMed - indexed for MEDLINE]
12.

A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2.

Lindwasser OW, Smith WJ, Chaudhuri R, Yang P, Hurley JH, Bonifacino JS.

J Virol. 2008 Feb;82(3):1166-74. Epub 2007 Nov 21.

PMID:
18032517
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Mutations in the AP1S2 gene encoding the sigma 2 subunit of the adaptor protein 1 complex are associated with syndromic X-linked mental retardation with hydrocephalus and calcifications in basal ganglia.

Saillour Y, Zanni G, Des Portes V, Heron D, Guibaud L, Iba-Zizen MT, Pedespan JL, Poirier K, Castelnau L, Julien C, Franconnet C, Bonthron D, Porteous ME, Chelly J, Bienvenu T.

J Med Genet. 2007 Nov;44(11):739-44. Epub 2007 Jul 6.

PMID:
17617514
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The gamma/sigma1 and alpha/sigma2 hemicomplexes of clathrin adaptors AP-1 and AP-2 harbor the dileucine recognition site.

Doray B, Lee I, Knisely J, Bu G, Kornfeld S.

Mol Biol Cell. 2007 May;18(5):1887-96. Epub 2007 Mar 14.

PMID:
17360967
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor.

Chaudhuri R, Lindwasser OW, Smith WJ, Hurley JH, Bonifacino JS.

J Virol. 2007 Apr;81(8):3877-90. Epub 2007 Jan 31.

PMID:
17267500
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation.

Tarpey PS, Stevens C, Teague J, Edkins S, O'Meara S, Avis T, Barthorpe S, Buck G, Butler A, Cole J, Dicks E, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, West S, Widaa S, Yates A, Catford R, Butler J, Mallya U, Moon J, Luo Y, Dorkins H, Thompson D, Easton DF, Wooster R, Bobrow M, Carpenter N, Simensen RJ, Schwartz CE, Stevenson RE, Turner G, Partington M, Gecz J, Stratton MR, Futreal PA, Raymond FL.

Am J Hum Genet. 2006 Dec;79(6):1119-24. Epub 2006 Nov 1.

PMID:
17186471
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes.

Theos AC, Tenza D, Martina JA, Hurbain I, Peden AA, Sviderskaya EV, Stewart A, Robinson MS, Bennett DC, Cutler DF, Bonifacino JS, Marks MS, Raposo G.

Mol Biol Cell. 2005 Nov;16(11):5356-72. Epub 2005 Sep 14.

PMID:
16162817
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Phosphatidylinositol-(4,5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2.

Höning S, Ricotta D, Krauss M, Späte K, Spolaore B, Motley A, Robinson M, Robinson C, Haucke V, Owen DJ.

Mol Cell. 2005 May 27;18(5):519-31. Erratum in: Mol Cell. 2005 Aug 19;19(4):577.

PMID:
15916959
[PubMed - indexed for MEDLINE]
Free Article
19.

Crystal structure of the clathrin adaptor protein 1 core.

Heldwein EE, Macia E, Wang J, Yin HL, Kirchhausen T, Harrison SC.

Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14108-13. Epub 2004 Sep 17.

PMID:
15377783
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Adaptable adaptors for coated vesicles.

Robinson MS.

Trends Cell Biol. 2004 Apr;14(4):167-74. Review.

PMID:
15066634
[PubMed - indexed for MEDLINE]

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