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Items: 1 to 20 of 39

1.

Common SNPs explain a large proportion of the heritability for human height.

Yang J, Benyamin B, McEvoy BP, Gordon S, Henders AK, Nyholt DR, Madden PA, Heath AC, Martin NG, Montgomery GW, Goddard ME, Visscher PM.

Nat Genet. 2010 Jul;42(7):565-9. doi: 10.1038/ng.608. Epub 2010 Jun 20.

2.

Replication of CLU, CR1, and PICALM associations with alzheimer disease.

Carrasquillo MM, Belbin O, Hunter TA, Ma L, Bisceglio GD, Zou F, Crook JE, Pankratz VS, Dickson DW, Graff-Radford NR, Petersen RC, Morgan K, Younkin SG.

Arch Neurol. 2010 Aug;67(8):961-4. doi: 10.1001/archneurol.2010.147. Epub 2010 Jun 14.

3.

Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.

Corneveaux JJ, Myers AJ, Allen AN, Pruzin JJ, Ramirez M, Engel A, Nalls MA, Chen K, Lee W, Chewning K, Villa SE, Meechoovet HB, Gerber JD, Frost D, Benson HL, O'Reilly S, Chibnik LB, Shulman JM, Singleton AB, Craig DW, Van Keuren-Jensen KR, Dunckley T, Bennett DA, De Jager PL, Heward C, Hardy J, Reiman EM, Huentelman MJ.

Hum Mol Genet. 2010 Aug 15;19(16):3295-301. doi: 10.1093/hmg/ddq221. Epub 2010 Jun 9.

4.

Implication of the immune system in Alzheimer's disease: evidence from genome-wide pathway analysis.

Lambert JC, Grenier-Boley B, Chouraki V, Heath S, Zelenika D, Fievet N, Hannequin D, Pasquier F, Hanon O, Brice A, Epelbaum J, Berr C, Dartigues JF, Tzourio C, Campion D, Lathrop M, Amouyel P.

J Alzheimers Dis. 2010;20(4):1107-18. doi: 10.3233/JAD-2010-100018.

PMID:
20413860
5.

Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.

Reynolds CA, Hong MG, Eriksson UK, Blennow K, Wiklund F, Johansson B, Malmberg B, Berg S, Alexeyenko A, Grönberg H, Gatz M, Pedersen NL, Prince JA.

Hum Mol Genet. 2010 May 15;19(10):2068-78. doi: 10.1093/hmg/ddq079. Epub 2010 Feb 18.

6.

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.

Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, Combarros O, Zelenika D, Bullido MJ, Tavernier B, Letenneur L, Bettens K, Berr C, Pasquier F, Fiévet N, Barberger-Gateau P, Engelborghs S, De Deyn P, Mateo I, Franck A, Helisalmi S, Porcellini E, Hanon O; European Alzheimer's Disease Initiative Investigators, de Pancorbo MM, Lendon C, Dufouil C, Jaillard C, Leveillard T, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Bossù P, Piccardi P, Annoni G, Seripa D, Galimberti D, Hannequin D, Licastro F, Soininen H, Ritchie K, Blanché H, Dartigues JF, Tzourio C, Gut I, Van Broeckhoven C, Alpérovitch A, Lathrop M, Amouyel P.

Nat Genet. 2009 Oct;41(10):1094-9. doi: 10.1038/ng.439. Epub 2009 Sep 6.

PMID:
19734903
7.

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.

Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, Heun R, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Holmans PA, O'Donovan M, Owen MJ, Williams J.

Nat Genet. 2009 Oct;41(10):1088-93. doi: 10.1038/ng.440. Epub 2009 Sep 6. Erratum in: Nat Genet. 2009 Oct;41(10):1156. Nat Genet. 2013 Jun;45(6):712. Haun, Reinhard [added].

8.
9.

Gene ontology analysis of GWA study data sets provides insights into the biology of bipolar disorder.

Holmans P, Green EK, Pahwa JS, Ferreira MA, Purcell SM, Sklar P; Wellcome Trust Case-Control Consortium, Owen MJ, O'Donovan MC, Craddock N.

Am J Hum Genet. 2009 Jul;85(1):13-24. doi: 10.1016/j.ajhg.2009.05.011. Epub 2009 Jun 18.

10.

Alzheimer's disease genetics current status and future perspectives.

Bertram L.

Int Rev Neurobiol. 2009;84:167-84. doi: 10.1016/S0074-7742(09)00409-7. Review.

PMID:
19501718
11.

The amyloid hypothesis for Alzheimer's disease: a critical reappraisal.

Hardy J.

J Neurochem. 2009 Aug;110(4):1129-34. doi: 10.1111/j.1471-4159.2009.06181.x. Epub 2009 May 18. Review.

12.

Strategies and issues in the detection of pathway enrichment in genome-wide association studies.

Hong MG, Pawitan Y, Magnusson PK, Prince JA.

Hum Genet. 2009 Aug;126(2):289-301. doi: 10.1007/s00439-009-0676-z. Epub 2009 May 1.

13.

Genomewide association studies--illuminating biologic pathways.

Hirschhorn JN.

N Engl J Med. 2009 Apr 23;360(17):1699-701. doi: 10.1056/NEJMp0808934. Epub 2009 Apr 15. No abstract available.

PMID:
19369661
14.

Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy.

Bu G.

Nat Rev Neurosci. 2009 May;10(5):333-44. doi: 10.1038/nrn2620. Epub 2009 Apr 2. Review.

15.

Pathway and network-based analysis of genome-wide association studies in multiple sclerosis.

Baranzini SE, Galwey NW, Wang J, Khankhanian P, Lindberg R, Pelletier D, Wu W, Uitdehaag BM, Kappos L; GeneMSA Consortium, Polman CH, Matthews PM, Hauser SL, Gibson RA, Oksenberg JR, Barnes MR.

Hum Mol Genet. 2009 Jun 1;18(11):2078-90. doi: 10.1093/hmg/ddp120. Epub 2009 Mar 13.

16.

Clearance mechanisms of Alzheimer's amyloid-beta peptide: implications for therapeutic design and diagnostic tests.

Bates KA, Verdile G, Li QX, Ames D, Hudson P, Masters CL, Martins RN.

Mol Psychiatry. 2009 May;14(5):469-86. doi: 10.1038/mp.2008.96. Epub 2008 Sep 16. Review. Erratum in: Mol Psychiatry. 2009 Dec;14(12):1144.

PMID:
18794889
17.

Vascular risk factors, cognitive decline, and dementia.

Duron E, Hanon O.

Vasc Health Risk Manag. 2008;4(2):363-81. Review.

18.

ApoE promotes the proteolytic degradation of Abeta.

Jiang Q, Lee CY, Mandrekar S, Wilkinson B, Cramer P, Zelcer N, Mann K, Lamb B, Willson TM, Collins JL, Richardson JC, Smith JD, Comery TA, Riddell D, Holtzman DM, Tontonoz P, Landreth GE.

Neuron. 2008 Jun 12;58(5):681-93. doi: 10.1016/j.neuron.2008.04.010.

19.

Cholesterol as a risk factor for dementia and cognitive decline: a systematic review of prospective studies with meta-analysis.

Anstey KJ, Lipnicki DM, Low LF.

Am J Geriatr Psychiatry. 2008 May;16(5):343-54. doi: 10.1097/JGP.0b013e31816b72d4.

PMID:
18448847
20.

On multiple-testing correction in genome-wide association studies.

Moskvina V, Schmidt KM.

Genet Epidemiol. 2008 Sep;32(6):567-73. doi: 10.1002/gepi.20331.

PMID:
18425821
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