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Items: 1 to 20 of 27

1.

Separation and detection of large phosphoproteins using Phos-tag SDS-PAGE.

Kinoshita E, Kinoshita-Kikuta E, Koike T.

Nat Protoc. 2009;4(10):1513-21. doi: 10.1038/nprot.2009.154. Epub 2009 Sep 24.

PMID:
19798084
2.

PP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpoint.

Nakada S, Chen GI, Gingras AC, Durocher D.

EMBO Rep. 2008 Oct;9(10):1019-26. doi: 10.1038/embor.2008.162. Epub 2008 Aug 29. Erratum in: EMBO Rep. 2008 Dec;9(12):1251.

3.

A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication.

Chowdhury D, Xu X, Zhong X, Ahmed F, Zhong J, Liao J, Dykxhoorn DM, Weinstock DM, Pfeifer GP, Lieberman J.

Mol Cell. 2008 Jul 11;31(1):33-46. doi: 10.1016/j.molcel.2008.05.016.

4.

Checkpoints meet the transcription at a novel histone milestone (H3-T11).

Shimada M, Nakanishi M.

Cell Cycle. 2008 Jun 1;7(11):1555-9. Epub 2008 Apr 2.

PMID:
18469531
5.

Chk1 is a histone H3 threonine 11 kinase that regulates DNA damage-induced transcriptional repression.

Shimada M, Niida H, Zineldeen DH, Tagami H, Tanaka M, Saito H, Nakanishi M.

Cell. 2008 Jan 25;132(2):221-32. doi: 10.1016/j.cell.2007.12.013.

6.

The DNA damage response: ten years after.

Harper JW, Elledge SJ.

Mol Cell. 2007 Dec 14;28(5):739-45. Review.

7.

Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation.

Metzger E, Yin N, Wissmann M, Kunowska N, Fischer K, Friedrichs N, Patnaik D, Higgins JM, Potier N, Scheidtmann KH, Buettner R, Schüle R.

Nat Cell Biol. 2008 Jan;10(1):53-60. Epub 2007 Dec 9. Erratum in: Nat Cell Biol. 2008 Feb;10(2):245.

9.

Emerging roles of nuclear protein phosphatases.

Moorhead GB, Trinkle-Mulcahy L, Ulke-Lemée A.

Nat Rev Mol Cell Biol. 2007 Mar;8(3):234-44. Review.

PMID:
17318227
10.

Specific role of Chk1 phosphorylations in cell survival and checkpoint activation.

Niida H, Katsuno Y, Banerjee B, Hande MP, Nakanishi M.

Mol Cell Biol. 2007 Apr;27(7):2572-81. Epub 2007 Jan 22.

11.
12.

Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1.

Vassilev LT, Tovar C, Chen S, Knezevic D, Zhao X, Sun H, Heimbrook DC, Chen L.

Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10660-5. Epub 2006 Jul 3.

13.

Repo-Man recruits PP1 gamma to chromatin and is essential for cell viability.

Trinkle-Mulcahy L, Andersen J, Lam YW, Moorhead G, Mann M, Lamond AI.

J Cell Biol. 2006 Feb 27;172(5):679-92. Epub 2006 Feb 21.

14.

Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response.

Smits VA, Reaper PM, Jackson SP.

Curr Biol. 2006 Jan 24;16(2):150-9. Epub 2005 Dec 15.

15.

gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair.

Chowdhury D, Keogh MC, Ishii H, Peterson CL, Buratowski S, Lieberman J.

Mol Cell. 2005 Dec 9;20(5):801-9. Epub 2005 Nov 28.

16.

A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery.

Keogh MC, Kim JA, Downey M, Fillingham J, Chowdhury D, Harrison JC, Onishi M, Datta N, Galicia S, Emili A, Lieberman J, Shen X, Buratowski S, Haber JE, Durocher D, Greenblatt JF, Krogan NJ.

Nature. 2006 Jan 26;439(7075):497-501. Epub 2005 Nov 20.

PMID:
16299494
17.

Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe.

Niida H, Tsuge S, Katsuno Y, Konishi A, Takeda N, Nakanishi M.

J Biol Chem. 2005 Nov 25;280(47):39246-52. Epub 2005 Sep 13.

18.

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints.

Sancar A, Lindsey-Boltz LA, Unsal-Kaçmaz K, Linn S.

Annu Rev Biochem. 2004;73:39-85. Review.

PMID:
15189136
19.
20.

Novel mitosis-specific phosphorylation of histone H3 at Thr11 mediated by Dlk/ZIP kinase.

Preuss U, Landsberg G, Scheidtmann KH.

Nucleic Acids Res. 2003 Feb 1;31(3):878-85.

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