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Items: 1 to 20 of 66

1.

Cardiac functional improvement in rats with myocardial infarction by up-regulating cardiac myosin light chain kinase with neuregulin.

Gu X, Liu X, Xu D, Li X, Yan M, Qi Y, Yan W, Wang W, Pan J, Xu Y, Xi B, Cheng L, Jia J, Wang K, Ge J, Zhou M.

Cardiovasc Res. 2010 Nov 1;88(2):334-43. doi: 10.1093/cvr/cvq223. Epub 2010 Jul 8.

2.

Narrative review: harnessing molecular genetics for the diagnosis and management of hypertrophic cardiomyopathy.

Wang L, Seidman JG, Seidman CE.

Ann Intern Med. 2010 Apr 20;152(8):513-20, W181. doi: 10.7326/0003-4819-152-8-201004200-00008. Review.

3.

Differential roles of regulatory light chain and myosin binding protein-C phosphorylations in the modulation of cardiac force development.

Colson BA, Locher MR, Bekyarova T, Patel JR, Fitzsimons DP, Irving TC, Moss RL.

J Physiol. 2010 Mar 15;588(Pt 6):981-93. doi: 10.1113/jphysiol.2009.183897. Epub 2010 Feb 1.

4.

Cardiac myosin is a substrate for zipper-interacting protein kinase (ZIPK).

Chang AN, Chen G, Gerard RD, Kamm KE, Stull JT.

J Biol Chem. 2010 Feb 19;285(8):5122-6. doi: 10.1074/jbc.C109.076489. Epub 2009 Dec 28.

5.

Heart-specific deletion of CnB1 reveals multiple mechanisms whereby calcineurin regulates cardiac growth and function.

Maillet M, Davis J, Auger-Messier M, York A, Osinska H, Piquereau J, Lorenz JN, Robbins J, Ventura-Clapier R, Molkentin JD.

J Biol Chem. 2010 Feb 26;285(9):6716-24. doi: 10.1074/jbc.M109.056143. Epub 2009 Dec 27.

6.

Myosin light chain kinase is necessary for tonic airway smooth muscle contraction.

Zhang WC, Peng YJ, Zhang GS, He WQ, Qiao YN, Dong YY, Gao YQ, Chen C, Zhang CH, Li W, Shen HH, Ning W, Kamm KE, Stull JT, Gao X, Zhu MS.

J Biol Chem. 2010 Feb 19;285(8):5522-31. doi: 10.1074/jbc.M109.062836. Epub 2009 Dec 14.

7.

Overexpression of myosin phosphatase reduces Ca(2+) sensitivity of contraction and impairs cardiac function.

Mizutani H, Okamoto R, Moriki N, Konishi K, Taniguchi M, Fujita S, Dohi K, Onishi K, Suzuki N, Satoh S, Makino N, Itoh T, Hartshorne DJ, Ito M.

Circ J. 2010 Jan;74(1):120-8. Epub 2009 Dec 7.

8.

Conditional ablation of nonmuscle myosin II-B delineates heart defects in adult mice.

Ma X, Takeda K, Singh A, Yu ZX, Zerfas P, Blount A, Liu C, Towbin JA, Schneider MD, Adelstein RS, Wei Q.

Circ Res. 2009 Nov 20;105(11):1102-9. doi: 10.1161/CIRCRESAHA.109.200303. Epub 2009 Oct 8.

9.

Signaling processes for initiating smooth muscle contraction upon neural stimulation.

Ding HL, Ryder JW, Stull JT, Kamm KE.

J Biol Chem. 2009 Jun 5;284(23):15541-8. doi: 10.1074/jbc.M900888200. Epub 2009 Apr 6.

10.

Diastolic dysfunction in familial hypertrophic cardiomyopathy transgenic model mice.

Abraham TP, Jones M, Kazmierczak K, Liang HY, Pinheiro AC, Wagg CS, Lopaschuk GD, Szczesna-Cordary D.

Cardiovasc Res. 2009 Apr 1;82(1):84-92. doi: 10.1093/cvr/cvp016. Epub 2009 Jan 15.

11.

Ablation of ventricular myosin regulatory light chain phosphorylation in mice causes cardiac dysfunction in situ and affects neighboring myofilament protein phosphorylation.

Scruggs SB, Hinken AC, Thawornkaiwong A, Robbins J, Walker LA, de Tombe PP, Geenen DL, Buttrick PM, Solaro RJ.

J Biol Chem. 2009 Feb 20;284(8):5097-106. doi: 10.1074/jbc.M807414200. Epub 2008 Dec 23.

12.
13.

Differential integration of Ca2+-calmodulin signal in intact ventricular myocytes at low and high affinity Ca2+-calmodulin targets.

Song Q, Saucerman JJ, Bossuyt J, Bers DM.

J Biol Chem. 2008 Nov 14;283(46):31531-40. doi: 10.1074/jbc.M804902200. Epub 2008 Sep 12.

14.

Calmodulin mediates differential sensitivity of CaMKII and calcineurin to local Ca2+ in cardiac myocytes.

Saucerman JJ, Bers DM.

Biophys J. 2008 Nov 15;95(10):4597-612. doi: 10.1529/biophysj.108.128728. Epub 2008 Aug 8.

15.

Myosin light chain kinase is central to smooth muscle contraction and required for gastrointestinal motility in mice.

He WQ, Peng YJ, Zhang WC, Lv N, Tang J, Chen C, Zhang CH, Gao S, Chen HQ, Zhi G, Feil R, Kamm KE, Stull JT, Gao X, Zhu MS.

Gastroenterology. 2008 Aug;135(2):610-20. doi: 10.1053/j.gastro.2008.05.032. Epub 2008 May 15.

16.

Multiplex kinase signaling modifies cardiac function at the level of sarcomeric proteins.

Solaro RJ.

J Biol Chem. 2008 Oct 3;283(40):26829-33. doi: 10.1074/jbc.R800037200. Epub 2008 Jun 19. Review. No abstract available.

17.

Myosin regulatory light chain phosphorylation attenuates cardiac hypertrophy.

Huang J, Shelton JM, Richardson JA, Kamm KE, Stull JT.

J Biol Chem. 2008 Jul 11;283(28):19748-56. doi: 10.1074/jbc.M802605200. Epub 2008 May 12.

18.

Cardiac plasticity.

Hill JA, Olson EN.

N Engl J Med. 2008 Mar 27;358(13):1370-80. doi: 10.1056/NEJMra072139. Review. No abstract available.

PMID:
18367740
19.

Identification of cardiac-specific myosin light chain kinase.

Chan JY, Takeda M, Briggs LE, Graham ML, Lu JT, Horikoshi N, Weinberg EO, Aoki H, Sato N, Chien KR, Kasahara H.

Circ Res. 2008 Mar 14;102(5):571-80. doi: 10.1161/CIRCRESAHA.107.161687. Epub 2008 Jan 17.

20.

A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart.

Seguchi O, Takashima S, Yamazaki S, Asakura M, Asano Y, Shintani Y, Wakeno M, Minamino T, Kondo H, Furukawa H, Nakamaru K, Naito A, Takahashi T, Ohtsuka T, Kawakami K, Isomura T, Kitamura S, Tomoike H, Mochizuki N, Kitakaze M.

J Clin Invest. 2007 Oct;117(10):2812-24.

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