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Results: 1 to 20 of 44

1.

Age-dependent and cell-population-restricted LRRK2 expression in normal mouse spleen.

Maekawa T, Kubo M, Yokoyama I, Ohta E, Obata F.

Biochem Biophys Res Commun. 2010 Feb 12;392(3):431-5. doi: 10.1016/j.bbrc.2010.01.041. Epub 2010 Jan 15.

PMID:
20079710
[PubMed - indexed for MEDLINE]
2.

The role of infection in the aetiology of inflammatory bowel disease.

Hansen R, Thomson JM, El-Omar EM, Hold GL.

J Gastroenterol. 2010 Mar;45(3):266-76. doi: 10.1007/s00535-009-0191-y. Review.

PMID:
20076977
[PubMed - indexed for MEDLINE]
3.

The WD40 domain is required for LRRK2 neurotoxicity.

Jorgensen ND, Peng Y, Ho CC, Rideout HJ, Petrey D, Liu P, Dauer WT.

PLoS One. 2009 Dec 24;4(12):e8463. doi: 10.1371/journal.pone.0008463.

PMID:
20041156
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Genomewide association study of leprosy.

Zhang FR, Huang W, Chen SM, Sun LD, Liu H, Li Y, Cui Y, Yan XX, Yang HT, Yang RD, Chu TS, Zhang C, Zhang L, Han JW, Yu GQ, Quan C, Yu YX, Zhang Z, Shi BQ, Zhang LH, Cheng H, Wang CY, Lin Y, Zheng HF, Fu XA, Zuo XB, Wang Q, Long H, Sun YP, Cheng YL, Tian HQ, Zhou FS, Liu HX, Lu WS, He SM, Du WL, Shen M, Jin QY, Wang Y, Low HQ, Erwin T, Yang NH, Li JY, Zhao X, Jiao YL, Mao LG, Yin G, Jiang ZX, Wang XD, Yu JP, Hu ZH, Gong CH, Liu YQ, Liu RY, Wang DM, Wei D, Liu JX, Cao WK, Cao HZ, Li YP, Yan WG, Wei SY, Wang KJ, Hibberd ML, Yang S, Zhang XJ, Liu JJ.

N Engl J Med. 2009 Dec 31;361(27):2609-18. doi: 10.1056/NEJMoa0903753. Epub 2009 Dec 16.

PMID:
20018961
[PubMed - indexed for MEDLINE]
Free Article
5.

Unexpected lack of hypersensitivity in LRRK2 knock-out mice to MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine).

Andres-Mateos E, Mejias R, Sasaki M, Li X, Lin BM, Biskup S, Zhang L, Banerjee R, Thomas B, Yang L, Liu G, Beal MF, Huso DL, Dawson TM, Dawson VL.

J Neurosci. 2009 Dec 16;29(50):15846-50. doi: 10.1523/JNEUROSCI.4357-09.2009.

PMID:
20016100
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Genome-wide association study reveals genetic risk underlying Parkinson's disease.

Simón-Sánchez J, Schulte C, Bras JM, Sharma M, Gibbs JR, Berg D, Paisan-Ruiz C, Lichtner P, Scholz SW, Hernandez DG, Krüger R, Federoff M, Klein C, Goate A, Perlmutter J, Bonin M, Nalls MA, Illig T, Gieger C, Houlden H, Steffens M, Okun MS, Racette BA, Cookson MR, Foote KD, Fernandez HH, Traynor BJ, Schreiber S, Arepalli S, Zonozi R, Gwinn K, van der Brug M, Lopez G, Chanock SJ, Schatzkin A, Park Y, Hollenbeck A, Gao J, Huang X, Wood NW, Lorenz D, Deuschl G, Chen H, Riess O, Hardy JA, Singleton AB, Gasser T.

Nat Genet. 2009 Dec;41(12):1308-12. doi: 10.1038/ng.487. Epub 2009 Nov 15.

PMID:
19915575
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

LRRK2 enhances oxidative stress-induced neurotoxicity via its kinase activity.

Heo HY, Park JM, Kim CH, Han BS, Kim KS, Seol W.

Exp Cell Res. 2010 Feb 15;316(4):649-56. doi: 10.1016/j.yexcr.2009.09.014. Epub 2009 Sep 19.

PMID:
19769964
[PubMed - indexed for MEDLINE]
8.

LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model.

Alegre-Abarrategui J, Christian H, Lufino MM, Mutihac R, Venda LL, Ansorge O, Wade-Martins R.

Hum Mol Genet. 2009 Nov 1;18(21):4022-34. doi: 10.1093/hmg/ddp346. Epub 2009 Jul 29.

PMID:
19640926
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

LRRK2 in Parkinson's disease - drawing the curtain of penetrance: a commentary.

Krüger R.

BMC Med. 2008 Nov 5;6:33. doi: 10.1186/1741-7015-6-33.

PMID:
18986509
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Genome-wide association studies: a new window into immune-mediated diseases.

Xavier RJ, Rioux JD.

Nat Rev Immunol. 2008 Aug;8(8):631-43. doi: 10.1038/nri2361. Review.

PMID:
18654571
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.

Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ; NIDDK IBD Genetics Consortium, Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E; Belgian-French IBD Consortium; Wellcome Trust Case Control Consortium, Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwilliam R, Tremelling M, Deloukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ.

Nat Genet. 2008 Aug;40(8):955-62. doi: 10.1038/ng.175. Epub 2008 Jun 29.

PMID:
18587394
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

LRRK2 regulates synaptic vesicle endocytosis.

Shin N, Jeong H, Kwon J, Heo HY, Kwon JJ, Yun HJ, Kim CH, Han BS, Tong Y, Shen J, Hatano T, Hattori N, Kim KS, Chang S, Seol W.

Exp Cell Res. 2008 Jun 10;314(10):2055-65. doi: 10.1016/j.yexcr.2008.02.015. Epub 2008 Mar 5.

PMID:
18445495
[PubMed - indexed for MEDLINE]
13.

Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: Implications for Parkinson's disease.

Westerlund M, Belin AC, Anvret A, Bickford P, Olson L, Galter D.

Neuroscience. 2008 Mar 18;152(2):429-36. doi: 10.1016/j.neuroscience.2007.10.062. Epub 2008 Jan 10.

PMID:
18272292
[PubMed - indexed for MEDLINE]
14.

Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells.

Plowey ED, Cherra SJ 3rd, Liu YJ, Chu CT.

J Neurochem. 2008 May;105(3):1048-56. doi: 10.1111/j.1471-4159.2008.05217.x. Epub 2008 Jan 7.

PMID:
18182054
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Dynamic and redundant regulation of LRRK2 and LRRK1 expression.

Biskup S, Moore DJ, Rea A, Lorenz-Deperieux B, Coombes CE, Dawson VL, Dawson TM, West AB.

BMC Neurosci. 2007 Nov 28;8:102.

PMID:
18045479
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Nonsteroidal anti-inflammatory drugs may protect against Parkinson disease.

Wahner AD, Bronstein JM, Bordelon YM, Ritz B.

Neurology. 2007 Nov 6;69(19):1836-42.

PMID:
17984451
[PubMed - indexed for MEDLINE]
17.

Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells.

Hijikata A, Kitamura H, Kimura Y, Yokoyama R, Aiba Y, Bao Y, Fujita S, Hase K, Hori S, Ishii Y, Kanagawa O, Kawamoto H, Kawano K, Koseki H, Kubo M, Kurita-Miki A, Kurosaki T, Masuda K, Nakata M, Oboki K, Ohno H, Okamoto M, Okayama Y, O-Wang J, Saito H, Saito T, Sakuma M, Sato K, Sato K, Seino K, Setoguchi R, Tamura Y, Tanaka M, Taniguchi M, Taniuchi I, Teng A, Watanabe T, Watarai H, Yamasaki S, Ohara O.

Bioinformatics. 2007 Nov 1;23(21):2934-41. Epub 2007 Sep 24.

PMID:
17893089
[PubMed - indexed for MEDLINE]
Free Article
18.

Unravelling the pathogenesis of inflammatory bowel disease.

Xavier RJ, Podolsky DK.

Nature. 2007 Jul 26;448(7152):427-34. Review.

PMID:
17653185
[PubMed - indexed for MEDLINE]
19.

Mechanistic insight into the dominant mode of the Parkinson's disease-associated G2019S LRRK2 mutation.

Luzón-Toro B, Rubio de la Torre E, Delgado A, Pérez-Tur J, Hilfiker S.

Hum Mol Genet. 2007 Sep 1;16(17):2031-9. Epub 2007 Jun 20.

PMID:
17584768
[PubMed - indexed for MEDLINE]
Free Article
20.

Apoptotic mechanisms in mutant LRRK2-mediated cell death.

Iaccarino C, Crosio C, Vitale C, Sanna G, Carrì MT, Barone P.

Hum Mol Genet. 2007 Jun 1;16(11):1319-26. Epub 2007 Apr 4.

PMID:
17409193
[PubMed - indexed for MEDLINE]
Free Article

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