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Results: 1 to 20 of 54

1.

Pleiotropic functions of Rho GTPase signaling: a Trojan horse or Achilles' heel for breast cancer treatment?

McHenry PR, Vargo-Gogola T.

Curr Drug Targets. 2010 Sep;11(9):1043-58. Review.

PMID:
20545614
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression.

Heckman-Stoddard BM, Vargo-Gogola T, McHenry PR, Jiang V, Herrick MP, Hilsenbeck SG, Settleman J, Rosen JM.

Breast Cancer Res. 2009;11(4):R61. doi: 10.1186/bcr2352. Epub 2009 Aug 24.

PMID:
19703301
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Rho GTPase function in tumorigenesis.

Karlsson R, Pedersen ED, Wang Z, Brakebusch C.

Biochim Biophys Acta. 2009 Dec;1796(2):91-8. doi: 10.1016/j.bbcan.2009.03.003. Epub 2009 Mar 24. Review.

PMID:
19327386
[PubMed - indexed for MEDLINE]
4.

Cell biology of the movement of breast cancer cells: intracellular signalling and the actin cytoskeleton.

Jiang P, Enomoto A, Takahashi M.

Cancer Lett. 2009 Nov 1;284(2):122-30. doi: 10.1016/j.canlet.2009.02.034. Epub 2009 Mar 19. Review.

PMID:
19303207
[PubMed - indexed for MEDLINE]
5.

The cytoskeleton and cancer.

Hall A.

Cancer Metastasis Rev. 2009 Jun;28(1-2):5-14. doi: 10.1007/s10555-008-9166-3. Review.

PMID:
19153674
[PubMed - indexed for MEDLINE]
6.

Coordination of Rho and Rac GTPase function via p190B RhoGAP.

Bustos RI, Forget MA, Settleman JE, Hansen SH.

Curr Biol. 2008 Oct 28;18(20):1606-11. doi: 10.1016/j.cub.2008.09.019.

PMID:
18948007
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Tiam1-deficiency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice.

Strumane K, Rygiel T, van der Valk M, Collard JG.

J Cancer Res Clin Oncol. 2009 Jan;135(1):69-80. doi: 10.1007/s00432-008-0437-8. Epub 2008 Jul 1.

PMID:
18592271
[PubMed - indexed for MEDLINE]
8.

Rho GTPases in cancer cell biology.

Vega FM, Ridley AJ.

FEBS Lett. 2008 Jun 18;582(14):2093-101. doi: 10.1016/j.febslet.2008.04.039. Epub 2008 May 5. Review.

PMID:
18460342
[PubMed - indexed for MEDLINE]
Free Article
9.

Inhibition of MMP-3 or -9 suppresses lipopolysaccharide-induced expression of proinflammatory cytokines and iNOS in microglia.

Woo MS, Park JS, Choi IY, Kim WK, Kim HS.

J Neurochem. 2008 Jul;106(2):770-80. doi: 10.1111/j.1471-4159.2008.05430.x. Epub 2008 Apr 17.

PMID:
18419763
[PubMed - indexed for MEDLINE]
10.

The Rac activator Tiam1 prevents keratinocyte apoptosis by controlling ROS-mediated ERK phosphorylation.

Rygiel TP, Mertens AE, Strumane K, van der Kammen R, Collard JG.

J Cell Sci. 2008 Apr 15;121(Pt 8):1183-92. doi: 10.1242/jcs.017194. Epub 2008 Mar 18.

PMID:
18349077
[PubMed - indexed for MEDLINE]
Free Article
11.

Role of Rho GTPases in breast cancer.

Tang Y, Olufemi L, Wang MT, Nie D.

Front Biosci. 2008 Jan 1;13:759-76. Review.

PMID:
17981586
[PubMed - indexed for MEDLINE]
12.

Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development.

Heckman BM, Chakravarty G, Vargo-Gogola T, Gonzales-Rimbau M, Hadsell DL, Lee AV, Settleman J, Rosen JM.

Dev Biol. 2007 Sep 1;309(1):137-49. Epub 2007 Jul 10.

PMID:
17662267
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Matrix metalloproteinase 7 mediates mammary epithelial cell tumorigenesis through the ErbB4 receptor.

Lynch CC, Vargo-Gogola T, Martin MD, Fingleton B, Crawford HC, Matrisian LM.

Cancer Res. 2007 Jul 15;67(14):6760-7.

PMID:
17638887
[PubMed - indexed for MEDLINE]
Free Article
14.

Computational model explains high activity and rapid cycling of Rho GTPases within protein complexes.

Goryachev AB, Pokhilko AV.

PLoS Comput Biol. 2006 Dec 1;2(12):e172. Epub 2006 Oct 9. Erratum in: PLoS Comput Biol. 2007 Jul;3(7):e136.

PMID:
17140284
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Influencing cellular transformation by modulating the rates of GTP hydrolysis by Cdc42.

Fidyk N, Wang JB, Cerione RA.

Biochemistry. 2006 Jun 27;45(25):7750-62.

PMID:
16784226
[PubMed - indexed for MEDLINE]
16.

Rac1 links integrin-mediated adhesion to the control of lactational differentiation in mammary epithelia.

Akhtar N, Streuli CH.

J Cell Biol. 2006 Jun 5;173(5):781-93.

PMID:
16754961
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A critical role for the inflammatory response in a mouse model of preneoplastic progression.

Schwertfeger KL, Xian W, Kaplan AM, Burnett SH, Cohen DA, Rosen JM.

Cancer Res. 2006 Jun 1;66(11):5676-85.

PMID:
16740705
[PubMed - indexed for MEDLINE]
Free Article
18.

D4-GDI, a Rho GTPase regulator, promotes breast cancer cell invasiveness.

Zhang Y, Zhang B.

Cancer Res. 2006 Jun 1;66(11):5592-8.

PMID:
16740694
[PubMed - indexed for MEDLINE]
Free Article
19.

Activated ERK1/2 and phosphorylated oestrogen receptor alpha are associated with improved breast cancer survival in women treated with tamoxifen.

Bergqvist J, Elmberger G, Ohd J, Linderholm B, Bjohle J, Hellborg H, Nordgren H, Borg AL, Skoog L, Bergh J.

Eur J Cancer. 2006 May;42(8):1104-12. Epub 2006 Apr 5.

PMID:
16603346
[PubMed - indexed for MEDLINE]
20.

P190-B Rho GTPase-activating protein overexpression disrupts ductal morphogenesis and induces hyperplastic lesions in the developing mammary gland.

Vargo-Gogola T, Heckman BM, Gunther EJ, Chodosh LA, Rosen JM.

Mol Endocrinol. 2006 Jun;20(6):1391-405. Epub 2006 Feb 9.

PMID:
16469769
[PubMed - indexed for MEDLINE]

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