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Concerted action of cellular JNK and Pin1 restricts HIV-1 genome integration to activated CD4+ T lymphocytes.

Manganaro L, Lusic M, Gutierrez MI, Cereseto A, Del Sal G, Giacca M.

Nat Med. 2010 Mar;16(3):329-33. doi: 10.1038/nm.2102. Epub 2010 Feb 21.


Chemokine coreceptor signaling in HIV-1 infection and pathogenesis.

Wu Y, Yoder A.

PLoS Pathog. 2009 Dec;5(12):e1000520. doi: 10.1371/journal.ppat.1000520. Epub 2009 Dec 24. Review.


The HIV envelope but not VSV glycoprotein is capable of mediating HIV latent infection of resting CD4 T cells.

Yu D, Wang W, Yoder A, Spear M, Wu Y.

PLoS Pathog. 2009 Oct;5(10):e1000633. doi: 10.1371/journal.ppat.1000633. Epub 2009 Oct 23.


Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation.

Yang HC, Xing S, Shan L, O'Connell K, Dinoso J, Shen A, Zhou Y, Shrum CK, Han Y, Liu JO, Zhang H, Margolick JB, Siliciano RF.

J Clin Invest. 2009 Nov;119(11):3473-86. doi: 10.1172/JCI39199. Epub 2009 Oct 1.


Elevated levels of innate immune modulators in lymph nodes and blood are associated with more-rapid disease progression in simian immunodeficiency virus-infected monkeys.

Durudas A, Milush JM, Chen HL, Engram JC, Silvestri G, Sodora DL.

J Virol. 2009 Dec;83(23):12229-40. doi: 10.1128/JVI.01311-09. Epub 2009 Sep 16.


Homeostatic chemokines CCL19 and CCL21 promote inflammation in human immunodeficiency virus-infected patients with ongoing viral replication.

Damås JK, Landrø L, Fevang B, Heggelund L, Tjønnfjord GE, Fløisand Y, Halvorsen B, Frøland SS, Aukrust P.

Clin Exp Immunol. 2009 Sep;157(3):400-7. doi: 10.1111/j.1365-2249.2009.03976.x.


Isolation of a cellular factor that can reactivate latent HIV-1 without T cell activation.

Yang HC, Shen L, Siliciano RF, Pomerantz JL.

Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6321-6. doi: 10.1073/pnas.0809536106. Epub 2009 Mar 31.


Immunopathogenesis of hepatic flare in HIV/hepatitis B virus (HBV)-coinfected individuals after the initiation of HBV-active antiretroviral therapy.

Crane M, Oliver B, Matthews G, Avihingsanon A, Ubolyam S, Markovska V, Chang JJ, Dore GJ, Price P, Visvanathan K, French M, Ruxrungtham K, Lewin SR.

J Infect Dis. 2009 Apr 1;199(7):974-81. doi: 10.1086/597276.


Induction of a striking systemic cytokine cascade prior to peak viremia in acute human immunodeficiency virus type 1 infection, in contrast to more modest and delayed responses in acute hepatitis B and C virus infections.

Stacey AR, Norris PJ, Qin L, Haygreen EA, Taylor E, Heitman J, Lebedeva M, DeCamp A, Li D, Grove D, Self SG, Borrow P.

J Virol. 2009 Apr;83(8):3719-33. doi: 10.1128/JVI.01844-08. Epub 2009 Jan 28.


Determinants of the establishment of human immunodeficiency virus type 1 latency.

Duverger A, Jones J, May J, Bibollet-Ruche F, Wagner FA, Cron RQ, Kutsch O.

J Virol. 2009 Apr;83(7):3078-93. doi: 10.1128/JVI.02058-08. Epub 2009 Jan 14.


Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells.

Contreras X, Schweneker M, Chen CS, McCune JM, Deeks SG, Martin J, Peterlin BM.

J Biol Chem. 2009 Mar 13;284(11):6782-9. doi: 10.1074/jbc.M807898200. Epub 2009 Jan 9.


Enhanced levels of the CCR7 ligands CCL19 and CCL21 in HIV infection: correlation with viral load, disease progression and response to highly active antiretroviral therapy.

Damås JK, Landrø L, Fevang B, Heggelund L, Frøland SS, Aukrust P.

AIDS. 2009 Jan 2;23(1):135-8. doi: 10.1097/QAD.0b013e32831cf595.


An in vitro system to model the establishment and reactivation of HIV-1 latency.

Marini A, Harper JM, Romerio F.

J Immunol. 2008 Dec 1;181(11):7713-20.


Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells.

Bosque A, Planelles V.

Blood. 2009 Jan 1;113(1):58-65. doi: 10.1182/blood-2008-07-168393. Epub 2008 Oct 10.


HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.

Yoder A, Yu D, Dong L, Iyer SR, Xu X, Kelly J, Liu J, Wang W, Vorster PJ, Agulto L, Stephany DA, Cooper JN, Marsh JW, Wu Y.

Cell. 2008 Sep 5;134(5):782-92. doi: 10.1016/j.cell.2008.06.036.


Induction of the Galpha(q) signaling cascade by the human immunodeficiency virus envelope is required for virus entry.

Harmon B, Ratner L.

J Virol. 2008 Sep;82(18):9191-205. doi: 10.1128/JVI.00424-08. Epub 2008 Jul 16.


Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection.

Keele BF, Giorgi EE, Salazar-Gonzalez JF, Decker JM, Pham KT, Salazar MG, Sun C, Grayson T, Wang S, Li H, Wei X, Jiang C, Kirchherr JL, Gao F, Anderson JA, Ping LH, Swanstrom R, Tomaras GD, Blattner WA, Goepfert PA, Kilby JM, Saag MS, Delwart EL, Busch MP, Cohen MS, Montefiori DC, Haynes BF, Gaschen B, Athreya GS, Lee HY, Wood N, Seoighe C, Perelson AS, Bhattacharya T, Korber BT, Hahn BH, Shaw GM.

Proc Natl Acad Sci U S A. 2008 May 27;105(21):7552-7. doi: 10.1073/pnas.0802203105. Epub 2008 May 19.


The actin cytoskeleton in T cell activation.

Burkhardt JK, Carrizosa E, Shaffer MH.

Annu Rev Immunol. 2008;26:233-59. doi: 10.1146/annurev.immunol.26.021607.090347. Review.


Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy.

Chun TW, Nickle DC, Justement JS, Meyers JH, Roby G, Hallahan CW, Kottilil S, Moir S, Mican JM, Mullins JI, Ward DJ, Kovacs JA, Mannon PJ, Fauci AS.

J Infect Dis. 2008 Mar 1;197(5):714-20. doi: 10.1086/527324.


Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model.

Hirota K, Yoshitomi H, Hashimoto M, Maeda S, Teradaira S, Sugimoto N, Yamaguchi T, Nomura T, Ito H, Nakamura T, Sakaguchi N, Sakaguchi S.

J Exp Med. 2007 Nov 26;204(12):2803-12. Epub 2007 Nov 19.

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