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References for PMC Articles for PubMed (Select 20829789)


Ubiquitinated proteins activate the proteasome by binding to Usp14/Ubp6, which causes 20S gate opening.

Peth A, Besche HC, Goldberg AL.

Mol Cell. 2009 Dec 11;36(5):794-804. doi: 10.1016/j.molcel.2009.11.015.


The lysine 48 and lysine 63 ubiquitin conjugates are processed differently by the 26 s proteasome.

Jacobson AD, Zhang NY, Xu P, Han KJ, Noone S, Peng J, Liu CW.

J Biol Chem. 2009 Dec 18;284(51):35485-94. doi: 10.1074/jbc.M109.052928. Epub .


Targeting proteins for degradation.

Schrader EK, Harstad KG, Matouschek A.

Nat Chem Biol. 2009 Nov;5(11):815-22. doi: 10.1038/nchembio.250. Review. Erratum in: Nat Chem Biol. 2009 Dec;5(12):954.


The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions.

Chen PC, Qin LN, Li XM, Walters BJ, Wilson JA, Mei L, Wilson SM.

J Neurosci. 2009 Sep 2;29(35):10909-19. doi: 10.1523/JNEUROSCI.2635-09.2009.


The ubiquitin proteasome system in neuropathology.

Lehman NL.

Acta Neuropathol. 2009 Sep;118(3):329-47. doi: 10.1007/s00401-009-0560-x. Epub 2009 Jul 14. Review.


Ubiquitin degradation with its substrate, or as a monomer in a ubiquitination-independent mode, provides clues to proteasome regulation.

Shabek N, Herman-Bachinsky Y, Ciechanover A.

Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):11907-12. doi: 10.1073/pnas.0905746106. Epub 2009 Jul 6.


A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis.

Muchamuel T, Basler M, Aujay MA, Suzuki E, Kalim KW, Lauer C, Sylvain C, Ring ER, Shields J, Jiang J, Shwonek P, Parlati F, Demo SD, Bennett MK, Kirk CJ, Groettrup M.

Nat Med. 2009 Jul;15(7):781-7. doi: 10.1038/nm.1978. Epub 2009 Jun 14. Erratum in: Nat Med. 2009 Nov;15(11):1333.


Recognition and processing of ubiquitin-protein conjugates by the proteasome.

Finley D.

Annu Rev Biochem. 2009;78:477-513. doi: 10.1146/annurev.biochem.78.081507.101607. Review.


Tau pathophysiology in neurodegeneration: a tangled issue.

Spires-Jones TL, Stoothoff WH, de Calignon A, Jones PB, Hyman BT.

Trends Neurosci. 2009 Mar;32(3):150-9. doi: 10.1016/j.tins.2008.11.007. Epub 2009 Jan 21. Review.


Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process.

Tonoki A, Kuranaga E, Tomioka T, Hamazaki J, Murata S, Tanaka K, Miura M.

Mol Cell Biol. 2009 Feb;29(4):1095-106. doi: 10.1128/MCB.01227-08. Epub 2008 Dec 15.


Targeting the UPS as therapy in multiple myeloma.

Chauhan D, Bianchi G, Anderson KC.

BMC Biochem. 2008 Oct 21;9 Suppl 1:S1. doi: 10.1186/1471-2091-9-S1-S1. Review.


Transgenic rescue of ataxia mice reveals a male-specific sterility defect.

Crimmins S, Sutovsky M, Chen PC, Huffman A, Wheeler C, Swing DA, Roth K, Wilson J, Sutovsky P, Wilson S.

Dev Biol. 2009 Jan 1;325(1):33-42. doi: 10.1016/j.ydbio.2008.09.021. Epub 2008 Sep 27.


Proteasome subunit Rpn13 is a novel ubiquitin receptor.

Husnjak K, Elsasser S, Zhang N, Chen X, Randles L, Shi Y, Hofmann K, Walters KJ, Finley D, Dikic I.

Nature. 2008 May 22;453(7194):481-8. doi: 10.1038/nature06926.


Adapting proteostasis for disease intervention.

Balch WE, Morimoto RI, Dillin A, Kelly JW.

Science. 2008 Feb 15;319(5865):916-9. doi: 10.1126/science.1141448. Review.


Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome.

Koulich E, Li X, DeMartino GN.

Mol Biol Cell. 2008 Mar;19(3):1072-82. Epub 2007 Dec 27.


TDP-43 proteinopathies: neurodegenerative protein misfolding diseases without amyloidosis.

Kwong LK, Uryu K, Trojanowski JQ, Lee VM.

Neurosignals. 2008;16(1):41-51. Epub 2007 Dec 5. Review.


Protein oxidative modifications and replicative senescence of WI-38 human embryonic fibroblasts.

Ahmed EK, Picot CR, Bulteau AL, Friguet B.

Ann N Y Acad Sci. 2007 Nov;1119:88-96. Review.


Cellular turnover of the polyglutamine disease protein ataxin-3 is regulated by its catalytic activity.

Todi SV, Laco MN, Winborn BJ, Travis SM, Wen HM, Paulson HL.

J Biol Chem. 2007 Oct 5;282(40):29348-58. Epub 2007 Aug 10.


Screen for ISG15-crossreactive deubiquitinases.

Catic A, Fiebiger E, Korbel GA, Blom D, Galardy PJ, Ploegh HL.

PLoS One. 2007 Jul 25;2(7):e679.


A ubiquitin stress response induces altered proteasome composition.

Hanna J, Meides A, Zhang DP, Finley D.

Cell. 2007 May 18;129(4):747-59.

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