Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 24

1.

High-dose atorvastatin causes a rapid sustained increase in human serum PCSK9 and disrupts its correlation with LDL cholesterol.

Welder G, Zineh I, Pacanowski MA, Troutt JS, Cao G, Konrad RJ.

J Lipid Res. 2010 Sep;51(9):2714-21. doi: 10.1194/jlr.M008144. Epub 2010 Jun 5.

PMID:
20525997
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Indices of cholesterol metabolism and relative responsiveness to ezetimibe and simvastatin.

Lakoski SG, Xu F, Vega GL, Grundy SM, Chandalia M, Lam C, Lowe RS, Stepanavage ME, Musliner TA, Cohen JC, Hobbs HH.

J Clin Endocrinol Metab. 2010 Feb;95(2):800-9. doi: 10.1210/jc.2009-1952. Epub 2009 Dec 4. Erratum in: J Clin Endocrinol Metab. 2011 May;96(5):1582.

PMID:
19965915
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Statins and ezetimibe modulate plasma proprotein convertase subtilisin kexin-9 (PCSK9) levels.

Davignon J, Dubuc G.

Trans Am Clin Climatol Assoc. 2009;120:163-73.

PMID:
19768174
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Fenofibrate treatment increases human serum proprotein convertase subtilisin kexin type 9 levels.

Troutt JS, Alborn WE, Cao G, Konrad RJ.

J Lipid Res. 2010 Feb;51(2):345-51. doi: 10.1194/jlr.M000620. Epub 2009 Sep 8.

PMID:
19738285
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A new method for measurement of total plasma PCSK9: clinical applications.

Dubuc G, Tremblay M, Paré G, Jacques H, Hamelin J, Benjannet S, Boulet L, Genest J, Bernier L, Seidah NG, Davignon J.

J Lipid Res. 2010 Jan;51(1):140-9. doi: 10.1194/jlr.M900273-JLR200. Epub .

PMID:
19571328
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Genetic and metabolic determinants of plasma PCSK9 levels.

Lakoski SG, Lagace TA, Cohen JC, Horton JD, Hobbs HH.

J Clin Endocrinol Metab. 2009 Jul;94(7):2537-43. doi: 10.1210/jc.2009-0141. Epub 2009 Apr 7.

PMID:
19351729
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

PCSK9: a convertase that coordinates LDL catabolism.

Horton JD, Cohen JC, Hobbs HH.

J Lipid Res. 2009 Apr;50 Suppl:S172-7. doi: 10.1194/jlr.R800091-JLR200. Epub 2008 Nov 19.

PMID:
19020338
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Plasma PCSK9 levels are significantly modified by statins and fibrates in humans.

Mayne J, Dewpura T, Raymond A, Cousins M, Chaplin A, Lahey KA, Lahaye SA, Mbikay M, Ooi TC, Chrétien M.

Lipids Health Dis. 2008 Jun 11;7:22. doi: 10.1186/1476-511X-7-22.

PMID:
18547436
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Atorvastatin increases human serum levels of proprotein convertase subtilisin/kexin type 9.

Careskey HE, Davis RA, Alborn WE, Troutt JS, Cao G, Konrad RJ.

J Lipid Res. 2008 Feb;49(2):394-8. Epub 2007 Nov 21.

PMID:
18033751
[PubMed - indexed for MEDLINE]
Free Article
10.

Sterol-dependent regulation of proprotein convertase subtilisin/kexin type 9 expression by sterol-regulatory element binding protein-2.

Jeong HJ, Lee HS, Kim KS, Kim YK, Yoon D, Park SW.

J Lipid Res. 2008 Feb;49(2):399-409. Epub 2007 Oct 5.

PMID:
17921436
[PubMed - indexed for MEDLINE]
Free Article
11.

Serum proprotein convertase subtilisin kexin type 9 is correlated directly with serum LDL cholesterol.

Alborn WE, Cao G, Careskey HE, Qian YW, Subramaniam DR, Davies J, Conner EM, Konrad RJ.

Clin Chem. 2007 Oct;53(10):1814-9. Epub 2007 Aug 16.

PMID:
17702855
[PubMed - indexed for MEDLINE]
Free Article
12.

Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.

Cohen JC, Boerwinkle E, Mosley TH Jr, Hobbs HH.

N Engl J Med. 2006 Mar 23;354(12):1264-72.

PMID:
16554528
[PubMed - indexed for MEDLINE]
Free Article
13.

Missense mutations in the PCSK9 gene are associated with hypocholesterolemia and possibly increased response to statin therapy.

Berge KE, Ose L, Leren TP.

Arterioscler Thromb Vasc Biol. 2006 May;26(5):1094-100. Epub 2006 Jan 19.

PMID:
16424354
[PubMed - indexed for MEDLINE]
Free Article
14.

Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9.

Rashid S, Curtis DE, Garuti R, Anderson NN, Bashmakov Y, Ho YK, Hammer RE, Moon YA, Horton JD.

Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5374-9. Epub 2005 Apr 1.

PMID:
15805190
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

No association between plasma levels of plant sterols and atherosclerosis in mice and men.

Wilund KR, Yu L, Xu F, Vega GL, Grundy SM, Cohen JC, Hobbs HH.

Arterioscler Thromb Vasc Biol. 2004 Dec;24(12):2326-32. Epub 2004 Oct 28.

PMID:
15514206
[PubMed - indexed for MEDLINE]
Free Article
16.

Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes.

Horton JD, Shah NA, Warrington JA, Anderson NN, Park SW, Brown MS, Goldstein JL.

Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12027-32. Epub 2003 Sep 25.

PMID:
14512514
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Serum cholesterol in acute starvation: a report of 20 cases.

ENDE N.

J Nutr. 1960 May;71:85-90. No abstract available.

PMID:
13820231
[PubMed - indexed for MEDLINE]
Free Article
18.

Mutations in PCSK9 cause autosomal dominant hypercholesterolemia.

Abifadel M, Varret M, Rabès JP, Allard D, Ouguerram K, Devillers M, Cruaud C, Benjannet S, Wickham L, Erlich D, Derré A, Villéger L, Farnier M, Beucler I, Bruckert E, Chambaz J, Chanu B, Lecerf JM, Luc G, Moulin P, Weissenbach J, Prat A, Krempf M, Junien C, Seidah NG, Boileau C.

Nat Genet. 2003 Jun;34(2):154-6.

PMID:
12730697
[PubMed - indexed for MEDLINE]
19.

Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

Horton JD, Shimomura I, Brown MS, Hammer RE, Goldstein JL, Shimano H.

J Clin Invest. 1998 Jun 1;101(11):2331-9.

PMID:
9616204
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice.

Horton JD, Bashmakov Y, Shimomura I, Shimano H.

Proc Natl Acad Sci U S A. 1998 May 26;95(11):5987-92.

PMID:
9600904
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk