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Items: 1 to 20 of 40

1.

Neurodevelopmental mechanisms of schizophrenia: understanding disturbed postnatal brain maturation through neuregulin-1-ErbB4 and DISC1.

Jaaro-Peled H, Hayashi-Takagi A, Seshadri S, Kamiya A, Brandon NJ, Sawa A.

Trends Neurosci. 2009 Sep;32(9):485-95. doi: 10.1016/j.tins.2009.05.007. Epub 2009 Aug 26. Review.

2.

Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling.

Mao Y, Ge X, Frank CL, Madison JM, Koehler AN, Doud MK, Tassa C, Berry EM, Soda T, Singh KK, Biechele T, Petryshen TL, Moon RT, Haggarty SJ, Tsai LH.

Cell. 2009 Mar 20;136(6):1017-31. doi: 10.1016/j.cell.2008.12.044.

3.

Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease.

Beecham GW, Martin ER, Li YJ, Slifer MA, Gilbert JR, Haines JL, Pericak-Vance MA.

Am J Hum Genet. 2009 Jan;84(1):35-43. doi: 10.1016/j.ajhg.2008.12.008.

4.

DISC1, PDE4B, and NDE1 at the centrosome and synapse.

Bradshaw NJ, Ogawa F, Antolin-Fontes B, Chubb JE, Carlyle BC, Christie S, Claessens A, Porteous DJ, Millar JK.

Biochem Biophys Res Commun. 2008 Dec 26;377(4):1091-6. doi: 10.1016/j.bbrc.2008.10.120. Epub 2008 Nov 5. Erratum in: Biochem Biophys Res Commun. 2009 Jul 3;384(3):400.

PMID:
18983980
5.

Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements.

Hemming ML, Elias JE, Gygi SP, Selkoe DJ.

PLoS Biol. 2008 Oct 21;6(10):e257. doi: 10.1371/journal.pbio.0060257.

6.

Secreted APP regulates the function of full-length APP in neurite outgrowth through interaction with integrin beta1.

Young-Pearse TL, Chen AC, Chang R, Marquez C, Selkoe DJ.

Neural Dev. 2008 Jun 23;3:15. doi: 10.1186/1749-8104-3-15.

7.

Regulated proteolysis of APP and ApoE receptors.

Hoe HS, Rebeck GW.

Mol Neurobiol. 2008 Feb;37(1):64-72. doi: 10.1007/s12035-008-8017-0. Epub 2008 Apr 15. Review.

PMID:
18415033
8.

A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference.

Young-Pearse TL, Bai J, Chang R, Zheng JB, LoTurco JJ, Selkoe DJ.

J Neurosci. 2007 Dec 26;27(52):14459-69.

9.

Dissecting DISC1 function through protein-protein interactions.

Brandon NJ.

Biochem Soc Trans. 2007 Nov;35(Pt 5):1283-6. Review.

PMID:
17956330
10.

Amyloid precursor protein and Presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling.

Nizzari M, Venezia V, Repetto E, Caorsi V, Magrassi R, Gagliani MC, Carlo P, Florio T, Schettini G, Tacchetti C, Russo T, Diaspro A, Russo C.

J Biol Chem. 2007 May 4;282(18):13833-44. Epub 2007 Feb 21.

11.

DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1.

Taya S, Shinoda T, Tsuboi D, Asaki J, Nagai K, Hikita T, Kuroda S, Kuroda K, Shimizu M, Hirotsune S, Iwamatsu A, Kaibuchi K.

J Neurosci. 2007 Jan 3;27(1):15-26.

12.

Disrupted-in-schizophrenia-1 (DISC1): a key susceptibility factor for major mental illnesses.

Sawamura N, Sawa A.

Ann N Y Acad Sci. 2006 Nov;1086:126-33. Review.

PMID:
17185511
13.

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

Camargo LM, Collura V, Rain JC, Mizuguchi K, Hermjakob H, Kerrien S, Bonnert TP, Whiting PJ, Brandon NJ.

Mol Psychiatry. 2007 Jan;12(1):74-86. Epub 2006 Oct 17.

PMID:
17043677
14.

DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1.

Kamiya A, Tomoda T, Chang J, Takaki M, Zhan C, Morita M, Cascio MB, Elashvili S, Koizumi H, Takanezawa Y, Dickerson F, Yolken R, Arai H, Sawa A.

Hum Mol Genet. 2006 Nov 15;15(22):3313-23. Epub 2006 Oct 11.

15.

A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditions.

Ishizuka K, Paek M, Kamiya A, Sawa A.

Biol Psychiatry. 2006 Jun 15;59(12):1189-97. Review.

PMID:
16797264
16.

The X11/Mint family of adaptor proteins.

Rogelj B, Mitchell JC, Miller CC, McLoughlin DM.

Brain Res Rev. 2006 Sep;52(2):305-15. Epub 2006 Jun 9. Review.

PMID:
16764936
17.

DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex.

Kirkpatrick B, Xu L, Cascella N, Ozeki Y, Sawa A, Roberts RC.

J Comp Neurol. 2006 Jul 20;497(3):436-50.

PMID:
16736468
18.

A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development.

Kamiya A, Kubo K, Tomoda T, Takaki M, Youn R, Ozeki Y, Sawamura N, Park U, Kudo C, Okawa M, Ross CA, Hatten ME, Nakajima K, Sawa A.

Nat Cell Biol. 2005 Dec;7(12):1167-78. Epub 2005 Nov 20. Erratum in: Nat Cell Biol. 2006 Jan;8(1):100.

PMID:
16299498
19.

Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia.

Callicott JH, Straub RE, Pezawas L, Egan MF, Mattay VS, Hariri AR, Verchinski BA, Meyer-Lindenberg A, Balkissoon R, Kolachana B, Goldberg TE, Weinberger DR.

Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8627-32. Epub 2005 Jun 6.

20.

Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population.

Thomson PA, Wray NR, Millar JK, Evans KL, Hellard SL, Condie A, Muir WJ, Blackwood DH, Porteous DJ.

Mol Psychiatry. 2005 Jul;10(7):657-68, 616.

PMID:
15838535
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