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Results: 1 to 20 of 38

1.

Functional analysis of OMICs data and small molecule compounds in an integrated "knowledge-based" platform.

Nikolsky Y, Kirillov E, Zuev R, Rakhmatulin E, Nikolskaya T.

Methods Mol Biol. 2009;563:177-96. doi: 10.1007/978-1-60761-175-2_10.

PMID:
19597786
[PubMed - indexed for MEDLINE]
2.

Discernment of possible mechanisms of hepatotoxicity via biological processes over-represented by co-expressed genes.

Chou JW, Bushel PR.

BMC Genomics. 2009 Jun 18;10:272. doi: 10.1186/1471-2164-10-272.

PMID:
19538742
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Circulating microRNAs, potential biomarkers for drug-induced liver injury.

Wang K, Zhang S, Marzolf B, Troisch P, Brightman A, Hu Z, Hood LE, Galas DJ.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4402-7. doi: 10.1073/pnas.0813371106. Epub 2009 Feb 25.

PMID:
19246379
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Utility of plasma circulating mRNA as a marker to detect hepatic injury.

Kudo Y, Ochi T, Shimada H, Ogawa S, Shinjo K.

J Vet Med Sci. 2008 Sep;70(9):993-5.

PMID:
18840978
[PubMed - indexed for MEDLINE]
Free Article
5.

Gene expression profiles reflect sclerosing cholangitis activity in abcb4 (-/-) mice.

Nakken KE, Nygard S, Haaland TK, Berge KE, Ƙdegaard A, Labori KJ, Raeder MG.

Scand J Gastroenterol. 2009;44(2):211-8. doi: 10.1080/00365520802400867.

PMID:
18785065
[PubMed - indexed for MEDLINE]
6.

Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype.

Lobenhofer EK, Auman JT, Blackshear PE, Boorman GA, Bushel PR, Cunningham ML, Fostel JM, Gerrish K, Heinloth AN, Irwin RD, Malarkey DE, Merrick BA, Sieber SO, Tucker CJ, Ward SM, Wilson RE, Hurban P, Tennant RW, Paules RS.

Genome Biol. 2008;9(6):R100. doi: 10.1186/gb-2008-9-6-r100. Epub 2008 Jun 20.

PMID:
18570634
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Genes related to apoptosis predict necrosis of the liver as a phenotype observed in rats exposed to a compendium of hepatotoxicants.

Huang L, Heinloth AN, Zeng ZB, Paules RS, Bushel PR.

BMC Genomics. 2008 Jun 16;9:288. doi: 10.1186/1471-2164-9-288.

PMID:
18558008
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Cellular imaging predictions of clinical drug-induced liver injury.

Xu JJ, Henstock PV, Dunn MC, Smith AR, Chabot JR, de Graaf D.

Toxicol Sci. 2008 Sep;105(1):97-105. doi: 10.1093/toxsci/kfn109. Epub 2008 Jun 3.

PMID:
18524759
[PubMed - indexed for MEDLINE]
Free Article
9.

GOEAST: a web-based software toolkit for Gene Ontology enrichment analysis.

Zheng Q, Wang XJ.

Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W358-63. doi: 10.1093/nar/gkn276. Epub 2008 May 16.

PMID:
18487275
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis.

Rosas IO, Richards TJ, Konishi K, Zhang Y, Gibson K, Lokshin AE, Lindell KO, Cisneros J, Macdonald SD, Pardo A, Sciurba F, Dauber J, Selman M, Gochuico BR, Kaminski N.

PLoS Med. 2008 Apr 29;5(4):e93. doi: 10.1371/journal.pmed.0050093.

PMID:
18447576
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Cytochrome c: a non-invasive biomarker of drug-induced liver injury.

Miller TJ, Knapton A, Adeyemo O, Noory L, Weaver J, Hanig JP.

J Appl Toxicol. 2008 Oct;28(7):815-28. doi: 10.1002/jat.1347.

PMID:
18418843
[PubMed - indexed for MEDLINE]
12.

The current state of serum biomarkers of hepatotoxicity.

Ozer J, Ratner M, Shaw M, Bailey W, Schomaker S.

Toxicology. 2008 Mar 20;245(3):194-205. doi: 10.1016/j.tox.2007.11.021. Epub 2007 Dec 5. Review.

PMID:
18291570
[PubMed - indexed for MEDLINE]
13.

The plasma proteome, adductome and idiosyncratic toxicity in toxicoproteomics research.

Merrick BA.

Brief Funct Genomic Proteomic. 2008 Jan;7(1):35-49. doi: 10.1093/bfgp/eln004. Epub 2008 Feb 12. Review.

PMID:
18270218
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Neutralization of CXCL10 accelerates liver regeneration in carbon tetrachloride-induced acute liver injury.

Yoneyama H, Kai Y, Koyama J, Suzuki K, Kawachi H, Narumi S, Ichida T.

Med Mol Morphol. 2007 Dec;40(4):191-7. Epub 2007 Dec 21.

PMID:
18085377
[PubMed - indexed for MEDLINE]
15.

CXCL10 regulates liver innate immune response against ischemia and reperfusion injury.

Zhai Y, Shen XD, Gao F, Zhao A, Freitas MC, Lassman C, Luster AD, Busuttil RW, Kupiec-Weglinski JW.

Hepatology. 2008 Jan;47(1):207-14.

PMID:
18041715
[PubMed - indexed for MEDLINE]
16.

Blood gene expression signatures predict exposure levels.

Bushel PR, Heinloth AN, Li J, Huang L, Chou JW, Boorman GA, Malarkey DE, Houle CD, Ward SM, Wilson RE, Fannin RD, Russo MW, Watkins PB, Tennant RW, Paules RS.

Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18211-6. Epub 2007 Nov 2.

PMID:
17984051
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Extracting gene expression patterns and identifying co-expressed genes from microarray data reveals biologically responsive processes.

Chou JW, Zhou T, Kaufmann WK, Paules RS, Bushel PR.

BMC Bioinformatics. 2007 Nov 2;8:427.

PMID:
17980031
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

CEBS--Chemical Effects in Biological Systems: a public data repository integrating study design and toxicity data with microarray and proteomics data.

Waters M, Stasiewicz S, Merrick BA, Tomer K, Bushel P, Paules R, Stegman N, Nehls G, Yost KJ, Johnson CH, Gustafson SF, Xirasagar S, Xiao N, Huang CC, Boyer P, Chan DD, Pan Q, Gong H, Taylor J, Choi D, Rashid A, Ahmed A, Howle R, Selkirk J, Tennant R, Fostel J.

Nucleic Acids Res. 2008 Jan;36(Database issue):D892-900. Epub 2007 Oct 25.

PMID:
17962311
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Role of neutrophils in the pathogenesis of acute inflammatory liver injury.

Ramaiah SK, Jaeschke H.

Toxicol Pathol. 2007 Oct;35(6):757-66. Review.

PMID:
17943649
[PubMed - indexed for MEDLINE]
Free Article
20.

Novel serum biomarker candidates for liver fibrosis in hepatitis C patients.

Gangadharan B, Antrobus R, Dwek RA, Zitzmann N.

Clin Chem. 2007 Oct;53(10):1792-9. Epub 2007 Aug 16.

PMID:
17702858
[PubMed - indexed for MEDLINE]
Free Article

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