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Results: 1 to 20 of 43

1.

Phosphoinositide-dependent protein kinase (PDK) activity regulates phosphatidylinositol 3,4,5-trisphosphate-dependent and -independent protein kinase B activation and chemotaxis.

Kamimura Y, Devreotes PN.

J Biol Chem. 2010 Mar 12;285(11):7938-46. doi: 10.1074/jbc.M109.089235. Epub 2010 Jan 14.

PMID:
20075071
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Assays for chemotaxis and chemoattractant-stimulated TorC2 activation and PKB substrate phosphorylation in Dictyostelium.

Kamimura Y, Tang M, Devreotes P.

Methods Mol Biol. 2009;571:255-70. doi: 10.1007/978-1-60761-198-1_17.

PMID:
19763972
[PubMed - indexed for MEDLINE]
3.

Group migration and signal relay in Dictyostelium.

Kriebel PW, Parent CA.

Methods Mol Biol. 2009;571:111-24. doi: 10.1007/978-1-60761-198-1_7.

PMID:
19763962
[PubMed - indexed for MEDLINE]
4.

Chemotaxis: finding the way forward with Dictyostelium.

King JS, Insall RH.

Trends Cell Biol. 2009 Oct;19(10):523-30. doi: 10.1016/j.tcb.2009.07.004. Epub 2009 Sep 3. Review.

PMID:
19733079
[PubMed - indexed for MEDLINE]
5.

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.

Feldman ME, Apsel B, Uotila A, Loewith R, Knight ZA, Ruggero D, Shokat KM.

PLoS Biol. 2009 Feb 10;7(2):e38. doi: 10.1371/journal.pbio.1000038.

PMID:
19209957
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

An extrachromosomal, inducible expression system for Dictyostelium discoideum.

Veltman DM, Keizer-Gunnink I, Haastert PJ.

Plasmid. 2009 Mar;61(2):119-25. doi: 10.1016/j.plasmid.2008.11.002. Epub 2008 Dec 13.

PMID:
19046986
[PubMed - indexed for MEDLINE]
7.

Spatiotemporal regulation of Ras activity provides directional sensing.

Zhang S, Charest PG, Firtel RA.

Curr Biol. 2008 Oct 28;18(20):1587-93. doi: 10.1016/j.cub.2008.08.069.

PMID:
18948008
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis.

Kamimura Y, Xiong Y, Iglesias PA, Hoeller O, Bolourani P, Devreotes PN.

Curr Biol. 2008 Jul 22;18(14):1034-43. doi: 10.1016/j.cub.2008.06.068.

PMID:
18635356
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Ras oncogenes: split personalities.

Karnoub AE, Weinberg RA.

Nat Rev Mol Cell Biol. 2008 Jul;9(7):517-31. doi: 10.1038/nrm2438. Review.

PMID:
18568040
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The TSC1-TSC2 complex is required for proper activation of mTOR complex 2.

Huang J, Dibble CC, Matsuzaki M, Manning BD.

Mol Cell Biol. 2008 Jun;28(12):4104-15. doi: 10.1128/MCB.00289-08. Epub 2008 Apr 14.

PMID:
18411301
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Navigating through models of chemotaxis.

Iglesias PA, Devreotes PN.

Curr Opin Cell Biol. 2008 Feb;20(1):35-40. doi: 10.1016/j.ceb.2007.11.011. Epub 2008 Jan 18. Review.

PMID:
18207721
[PubMed - indexed for MEDLINE]
12.

G protein-independent Ras/PI3K/F-actin circuit regulates basic cell motility.

Sasaki AT, Janetopoulos C, Lee S, Charest PG, Takeda K, Sundheimer LW, Meili R, Devreotes PN, Firtel RA.

J Cell Biol. 2007 Jul 16;178(2):185-91.

PMID:
17635933
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s.

Frias MA, Thoreen CC, Jaffe JD, Schroder W, Sculley T, Carr SA, Sabatini DM.

Curr Biol. 2006 Sep 19;16(18):1865-70. Epub 2006 Aug 17.

PMID:
16919458
[PubMed - indexed for MEDLINE]
Free Article
14.

Navigating signaling networks: chemotaxis in Dictyostelium discoideum.

Franca-Koh J, Kamimura Y, Devreotes P.

Curr Opin Genet Dev. 2006 Aug;16(4):333-8. Epub 2006 Jun 19. Review.

PMID:
16782326
[PubMed - indexed for MEDLINE]
15.

TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium.

Lee S, Comer FI, Sasaki A, McLeod IX, Duong Y, Okumura K, Yates JR 3rd, Parent CA, Firtel RA.

Mol Biol Cell. 2005 Oct;16(10):4572-83. Epub 2005 Aug 3.

PMID:
16079174
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization.

Kamada Y, Fujioka Y, Suzuki NN, Inagaki F, Wullschleger S, Loewith R, Hall MN, Ohsumi Y.

Mol Cell Biol. 2005 Aug;25(16):7239-48.

PMID:
16055732
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.

Sarbassov DD, Guertin DA, Ali SM, Sabatini DM.

Science. 2005 Feb 18;307(5712):1098-101.

PMID:
15718470
[PubMed - indexed for MEDLINE]
Free Article
18.

Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement.

Sasaki AT, Chun C, Takeda K, Firtel RA.

J Cell Biol. 2004 Nov 8;167(3):505-18.

PMID:
15534002
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A rapid and efficient method to generate multiple gene disruptions in Dictyostelium discoideum using a single selectable marker and the Cre-loxP system.

Faix J, Kreppel L, Shaulsky G, Schleicher M, Kimmel AR.

Nucleic Acids Res. 2004 Oct 26;32(19):e143.

PMID:
15507682
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.

Jacinto E, Loewith R, Schmidt A, Lin S, Rüegg MA, Hall A, Hall MN.

Nat Cell Biol. 2004 Nov;6(11):1122-8. Epub 2004 Oct 3.

PMID:
15467718
[PubMed - indexed for MEDLINE]

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