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Update in male osteoporosis.

Khosla S.

J Clin Endocrinol Metab. 2010 Jan;95(1):3-10. doi: 10.1210/jc.2009-1740. Review.


A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure.

Yadav VK, Oury F, Suda N, Liu ZW, Gao XB, Confavreux C, Klemenhagen KC, Tanaka KF, Gingrich JA, Guo XE, Tecott LH, Mann JJ, Hen R, Horvath TL, Karsenty G.

Cell. 2009 Sep 4;138(5):976-89. doi: 10.1016/j.cell.2009.06.051.


Relation of serum serotonin levels to bone density and structural parameters in women.

Mödder UI, Achenbach SJ, Amin S, Riggs BL, Melton LJ 3rd, Khosla S.

J Bone Miner Res. 2010 Feb;25(2):415-22. doi: 10.1359/jbmr.090721.


Dissociation of the neuronal regulation of bone mass and energy metabolism by leptin in vivo.

Shi Y, Yadav VK, Suda N, Liu XS, Guo XE, Myers MG Jr, Karsenty G.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20529-33. doi: 10.1073/pnas.0808701106. Epub 2008 Dec 11.


Androgens and bone.

Clarke BL, Khosla S.

Steroids. 2009 Mar;74(3):296-305. doi: 10.1016/j.steroids.2008.10.003. Epub 2008 Oct 17. Review.


Estrogen and fracture risk in men.

Gennari L, Khosla S, Bilezikian JP.

J Bone Miner Res. 2008 Oct;23(10):1548-51. doi: 10.1359/jbmr.0810c. No abstract available.


Older men with low serum estradiol and high serum SHBG have an increased risk of fractures.

Mellström D, Vandenput L, Mallmin H, Holmberg AH, Lorentzon M, Odén A, Johansson H, Orwoll ES, Labrie F, Karlsson MK, Ljunggren O, Ohlsson C.

J Bone Miner Res. 2008 Oct;23(10):1552-60. doi: 10.1359/jbmr.080518.


Osteoporosis in men.

Khosla S, Amin S, Orwoll E.

Endocr Rev. 2008 Jun;29(4):441-64. doi: 10.1210/er.2008-0002. Epub 2008 May 1. Review.


Comparison of sex steroid measurements in men by immunoassay versus mass spectroscopy and relationships with cortical and trabecular volumetric bone mineral density.

Khosla S, Amin S, Singh RJ, Atkinson EJ, Melton LJ 3rd, Riggs BL.

Osteoporos Int. 2008 Oct;19(10):1465-71. doi: 10.1007/s00198-008-0591-5. Epub 2008 Mar 13.


Regulation of bone turnover by sex steroids in men.

Sanyal A, Hoey KA, Mödder UI, Lamsam JL, McCready LK, Peterson JM, Achenbach SJ, Oursler MJ, Khosla S.

J Bone Miner Res. 2008 May;23(5):705-14.


A population-based assessment of rates of bone loss at multiple skeletal sites: evidence for substantial trabecular bone loss in young adult women and men.

Riggs BL, Melton LJ, Robb RA, Camp JJ, Atkinson EJ, McDaniel L, Amin S, Rouleau PA, Khosla S.

J Bone Miner Res. 2008 Feb;23(2):205-14.


Vitamin D deficiency.

Holick MF.

N Engl J Med. 2007 Jul 19;357(3):266-81. Review. No abstract available.


High serum IGFBP-2 is predictive of increased bone turnover in aging men and women.

Amin S, Riggs BL, Melton LJ 3rd, Achenbach SJ, Atkinson EJ, Khosla S.

J Bone Miner Res. 2007 Jun;22(6):799-807.


Effect of blockade of TNF-alpha and interleukin-1 action on bone resorption in early postmenopausal women.

Charatcharoenwitthaya N, Khosla S, Atkinson EJ, McCready LK, Riggs BL.

J Bone Miner Res. 2007 May;22(5):724-9.


Editorial: Sex hormone binding globulin: inhibitor or facilitator (or both) of sex steroid action?

Khosla S.

J Clin Endocrinol Metab. 2006 Dec;91(12):4764-6. No abstract available.


Does reduced skeletal loading account for age-related bone loss?

Melton LJ 3rd, Riggs BL, Achenbach SJ, Amin S, Camp JJ, Rouleau PA, Robb RA, Oberg AL, Khosla S.

J Bone Miner Res. 2006 Dec;21(12):1847-55.


Bone turnover across the menopause transition: correlations with inhibins and follicle-stimulating hormone.

Perrien DS, Achenbach SJ, Bledsoe SE, Walser B, Suva LJ, Khosla S, Gaddy D.

J Clin Endocrinol Metab. 2006 May;91(5):1848-54. Epub 2006 Jan 31.


Hormonal and biochemical determinants of trabecular microstructure at the ultradistal radius in women and men.

Khosla S, Melton LJ 3rd, Achenbach SJ, Oberg AL, Riggs BL.

J Clin Endocrinol Metab. 2006 Mar;91(3):885-91. Epub 2005 Dec 20.


Effects of sex and age on bone microstructure at the ultradistal radius: a population-based noninvasive in vivo assessment.

Khosla S, Riggs BL, Atkinson EJ, Oberg AL, McDaniel LJ, Holets M, Peterson JM, Melton LJ 3rd.

J Bone Miner Res. 2006 Jan;21(1):124-31. Epub 2005 Oct 3.


The role of the immune system in the pathophysiology of osteoporosis.

Clowes JA, Riggs BL, Khosla S.

Immunol Rev. 2005 Dec;208:207-27. Review.

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