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Items: 1 to 20 of 52


Gene set enrichment analysis made simple.

Irizarry RA, Wang C, Zhou Y, Speed TP.

Stat Methods Med Res. 2009 Dec;18(6):565-75. doi: 10.1177/0962280209351908. Erratum in: Stat Methods Med Res. 2011 Oct;20(5):571.


Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer.

Lin C, Yang L, Tanasa B, Hutt K, Ju BG, Ohgi K, Zhang J, Rose DW, Fu XD, Glass CK, Rosenfeld MG.

Cell. 2009 Dec 11;139(6):1069-83. doi: 10.1016/j.cell.2009.11.030. Epub .


Induced chromosomal proximity and gene fusions in prostate cancer.

Mani RS, Tomlins SA, Callahan K, Ghosh A, Nyati MK, Varambally S, Palanisamy N, Chinnaiyan AM.

Science. 2009 Nov 27;326(5957):1230. doi: 10.1126/science.1178124. Epub 2009 Oct 29.


Cancer statistics, 2009.

Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ.

CA Cancer J Clin. 2009 Jul-Aug;59(4):225-49. doi: 10.3322/caac.20006. Epub 2009 May 27.


Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate.

Carver BS, Tran J, Gopalan A, Chen Z, Shaikh S, Carracedo A, Alimonti A, Nardella C, Varmeh S, Scardino PT, Cordon-Cardo C, Gerald W, Pandolfi PP.

Nat Genet. 2009 May;41(5):619-24. doi: 10.1038/ng.370. Epub 2009 Apr 26.


Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis.

King JC, Xu J, Wongvipat J, Hieronymus H, Carver BS, Leung DH, Taylor BS, Sander C, Cardiff RD, Couto SS, Gerald WL, Sawyers CL.

Nat Genet. 2009 May;41(5):524-6. doi: 10.1038/ng.371. Epub 2009 Apr 26.


Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer.

Liu W, Laitinen S, Khan S, Vihinen M, Kowalski J, Yu G, Chen L, Ewing CM, Eisenberger MA, Carducci MA, Nelson WG, Yegnasubramanian S, Luo J, Wang Y, Xu J, Isaacs WB, Visakorpi T, Bova GS.

Nat Med. 2009 May;15(5):559-65. doi: 10.1038/nm.1944. Epub 2009 Apr 12. Erratum in: Nat Med. 2009 Jul;15(7):819.


Distinct genomic aberrations associated with ERG rearranged prostate cancer.

Demichelis F, Setlur SR, Beroukhim R, Perner S, Korbel JO, Lafargue CJ, Pflueger D, Pina C, Hofer MD, Sboner A, Svensson MA, Rickman DS, Urban A, Snyder M, Meyerson M, Lee C, Gerstein MB, Kuefer R, Rubin MA.

Genes Chromosomes Cancer. 2009 Apr;48(4):366-80. doi: 10.1002/gcc.20647.


Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer.

Lavin MF.

Nat Rev Mol Cell Biol. 2008 Oct;9(10):759-69. doi: 10.1038/nrm2514. Review. Erratum in: Nat Rev Mol Cell Biol. 2008 Dec;9(12). doi: 10.1038/nrm2514.


Chromosomal translocations: revisited yet again.

Rowley JD.

Blood. 2008 Sep 15;112(6):2183-9. doi: 10.1182/blood-2008-04-097931. Review. No abstract available.


Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin.

Kinner A, Wu W, Staudt C, Iliakis G.

Nucleic Acids Res. 2008 Oct;36(17):5678-94. doi: 10.1093/nar/gkn550. Epub 2008 Sep 4. Review.


Does prostate cancer co-opt the developmental program?

Marker PC.

Differentiation. 2008 Jul;76(6):736-44. doi: 10.1111/j.1432-0436.2008.00297.x. Review.


Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis.

Gurel B, Iwata T, Koh CM, Jenkins RB, Lan F, Van Dang C, Hicks JL, Morgan J, Cornish TC, Sutcliffe S, Isaacs WB, Luo J, De Marzo AM.

Mod Pathol. 2008 Sep;21(9):1156-67. doi: 10.1038/modpathol.2008.111. Epub 2008 Jun 20.


Recurrent gene fusions in prostate cancer.

Kumar-Sinha C, Tomlins SA, Chinnaiyan AM.

Nat Rev Cancer. 2008 Jul;8(7):497-511. doi: 10.1038/nrc2402. Epub 2008 Jun 19. Review.


Interaction and functional interference of glucocorticoid receptor and SOCS1.

Haffner MC, Jurgeit A, Berlato C, Geley S, Parajuli N, Yoshimura A, Doppler W.

J Biol Chem. 2008 Aug 8;283(32):22089-96. doi: 10.1074/jbc.M801041200. Epub 2008 Jun 4.


Two unique novel prostate-specific and androgen-regulated fusion partners of ETV4 in prostate cancer.

Hermans KG, Bressers AA, van der Korput HA, Dits NF, Jenster G, Trapman J.

Cancer Res. 2008 May 1;68(9):3094-8. doi: 10.1158/0008-5472.CAN-08-0198.


Genetic changes and DNA damage responses in the prostate.

Hällström TM, Laiho M.

Prostate. 2008 Jun 1;68(8):902-18. doi: 10.1002/pros.20746. Review.


Association of guanine nucleotide-exchange protein BIG1 in HepG2 cell nuclei with nucleolin, U3 snoRNA, and fibrillarin.

Padilla PI, Uhart M, Pacheco-Rodriguez G, Peculis BA, Moss J, Vaughan M.

Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3357-61. doi: 10.1073/pnas.0712387105. Epub 2008 Feb 21.


A causal role for ERG in neoplastic transformation of prostate epithelium.

Klezovitch O, Risk M, Coleman I, Lucas JM, Null M, True LD, Nelson PS, Vasioukhin V.

Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2105-10. doi: 10.1073/pnas.0711711105. Epub 2008 Feb 1.


Genome instability: a mechanistic view of its causes and consequences.

Aguilera A, Gómez-González B.

Nat Rev Genet. 2008 Mar;9(3):204-17. doi: 10.1038/nrg2268. Review.

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